BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 22796043)

  • 1. Indole based cyclooxygenase inhibitors: synthesis, biological evaluation, docking and NMR screening.
    Estevão MS; Carvalho LC; Freitas M; Gomes A; Viegas A; Manso J; Erhardt S; Fernandes E; Cabrita EJ; Marques MM
    Eur J Med Chem; 2012 Aug; 54():823-33. PubMed ID: 22796043
    [TBL] [Abstract][Full Text] [Related]  

  • 2. N-1 and C-3 substituted indole Schiff bases as selective COX-2 inhibitors: synthesis and biological evaluation.
    Kaur J; Bhardwaj A; Huang Z; Knaus EE
    Bioorg Med Chem Lett; 2012 Mar; 22(6):2154-9. PubMed ID: 22361134
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study.
    Abdel-Aziz AA; ElTahir KE; Asiri YA
    Eur J Med Chem; 2011 May; 46(5):1648-55. PubMed ID: 21388719
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel N-substituted indole Schiff bases as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase enzymes: Synthesis, biological activities in vitro and docking study.
    Lamie PF; Ali WAM; Bazgier V; Rárová L
    Eur J Med Chem; 2016 Nov; 123():803-813. PubMed ID: 27541263
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 3-methyl-2-phenyl-1-substituted-indole derivatives as indomethacin analogs: design, synthesis and biological evaluation as potential anti-inflammatory and analgesic agents.
    Abdellatif KR; Lamie PF; Omar HA
    J Enzyme Inhib Med Chem; 2016; 31(2):318-24. PubMed ID: 25798690
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors.
    Lai Y; Ma L; Huang W; Yu X; Zhang Y; Ji H; Tian J
    Bioorg Med Chem Lett; 2010 Dec; 20(24):7349-53. PubMed ID: 21055929
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and evaluation of dithiolethiones as novel cyclooxygenase inhibitors.
    Zanatta SD; Manallack DT; Jarrott B; Williams SJ
    Bioorg Med Chem Lett; 2009 Jan; 19(2):459-61. PubMed ID: 19056264
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, biological evaluation and docking study of novel indole-2-amide as anti-inflammatory agents with dual inhibition of COX and 5-LOX.
    Huang Y; Zhang B; Li J; Liu H; Zhang Y; Yang Z; Liu W
    Eur J Med Chem; 2019 Oct; 180():41-50. PubMed ID: 31299586
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, anti-inflammatory activity, and in vitro antitumor effect of a novel class of cyclooxygenase inhibitors: 4-(aryloyl)phenyl methyl sulfones.
    Harrak Y; Casula G; Basset J; Rosell G; Plescia S; Raffa D; Cusimano MG; Pouplana R; Pujol MD
    J Med Chem; 2010 Sep; 53(18):6560-71. PubMed ID: 20804197
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analogue-based design, synthesis and docking of non-steroidal anti-inflammatory agents. Part 2: methyl sulfanyl/methyl sulfonyl substituted 2,3-diaryl-2,3-dihydro-1H-quinazolin-4-ones.
    Manivannan E; Chaturvedi SC
    Bioorg Med Chem; 2012 Dec; 20(24):7119-27. PubMed ID: 23146282
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and screening of cyclooxygenase inhibitory activity of some 1,3-dioxoisoindoline derivatives.
    Cizmeciolu M; Pabuguoglu V; Ballar P; Pabuççuoğlu A; Soyer Z
    Arzneimittelforschung; 2011; 61(3):186-90. PubMed ID: 21528644
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study.
    El-Sayed MA; Abdel-Aziz NI; Abdel-Aziz AA; El-Azab AS; Asiri YA; Eltahir KE
    Bioorg Med Chem; 2011 Jun; 19(11):3416-24. PubMed ID: 21570309
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Syntheses and biological evaluation of indole-2 and 3-carboxamides: new selective cyclooxygenase-2 inhibitors.
    Olgen S; Güner E; Fabregat MA; Crespo MI; Nebioğlu D
    Pharmazie; 2002 Apr; 57(4):238-42. PubMed ID: 11998441
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives.
    Moraes ADTO; Miranda MDS; Jacob ÍTT; Amorim CADC; Moura RO; Silva SÂSD; Soares MBP; Almeida SMV; Souza TRCL; Oliveira JF; Silva TGD; Melo CML; Moreira DRM; Lima MDCA
    Bioorg Med Chem; 2018 Nov; 26(20):5388-5396. PubMed ID: 30293795
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs).
    Perrone MG; Vitale P; Panella A; Ferorelli S; Contino M; Lavecchia A; Scilimati A
    ChemMedChem; 2016 Jun; 11(11):1172-87. PubMed ID: 27136372
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel pyrazolopyrimidine derivatives targeting COXs and iNOS enzymes; design, synthesis and biological evaluation as potential anti-inflammatory agents.
    Abdelazeem AH; Abdelatef SA; El-Saadi MT; Omar HA; Khan SI; McCurdy CR; El-Moghazy SM
    Eur J Pharm Sci; 2014 Oct; 62():197-211. PubMed ID: 24907682
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Docking Studies, Synthesis and Biological Evaluation of β-aryl-β-hydroxy Propanoic Acids for Anti-inflammatory Activity.
    Savic J; Dilber S; Milenkovic M; Kotur-Stevuljevic J; Markovic B; Vladimirov S; Brboric J
    Med Chem; 2017; 13(2):186-195. PubMed ID: 27605092
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN; Chen QH; Knaus EE
    J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Syntheses and characterization of nimesulide derivatives for dual enzyme inhibitors of both cyclooxygenase-1/2 and 5-lipoxygenase.
    Li Y; Chen SH; Ou TM; Tan JH; Li D; Gu LQ; Huang ZS
    Bioorg Med Chem; 2011 Mar; 19(6):2074-83. PubMed ID: 21349729
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and cyclooxygenase inhibitory activities of some N-acylhydrazone derivatives of isoxazolo[4,5-d]pyridazin-4(5H)-ones.
    Unsal-Tan O; Ozden K; Rauk A; Balkan A
    Eur J Med Chem; 2010 Jun; 45(6):2345-52. PubMed ID: 20207453
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.