BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 22796453)

  • 21. Activation of orexin/hypocretin type 1 receptors stimulates cAMP synthesis in primary cultures of rat astrocytes.
    Woldan-Tambor A; Biegańska K; Wiktorowska-Owczarek A; Zawilska JB
    Pharmacol Rep; 2011; 63(3):717-23. PubMed ID: 21857082
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Regulation of OX1 orexin/hypocretin receptor-coupling to phospholipase C by Ca2+ influx.
    Johansson L; Ekholm ME; Kukkonen JP
    Br J Pharmacol; 2007 Jan; 150(1):97-104. PubMed ID: 17115071
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement.
    Shoblock JR; Welty N; Aluisio L; Fraser I; Motley ST; Morton K; Palmer J; Bonaventure P; Carruthers NI; Lovenberg TW; Boggs J; Galici R
    Psychopharmacology (Berl); 2011 May; 215(1):191-203. PubMed ID: 21181123
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Antagonism of rat orexin receptors by almorexant attenuates central chemoreception in wakefulness in the active period of the diurnal cycle.
    Li A; Nattie E
    J Physiol; 2010 Aug; 588(Pt 15):2935-44. PubMed ID: 20547681
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Blockade of orexin-1 receptors attenuates orexin-2 receptor antagonism-induced sleep promotion in the rat.
    Dugovic C; Shelton JE; Aluisio LE; Fraser IC; Jiang X; Sutton SW; Bonaventure P; Yun S; Li X; Lord B; Dvorak CA; Carruthers NI; Lovenberg TW
    J Pharmacol Exp Ther; 2009 Jul; 330(1):142-51. PubMed ID: 19363060
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Orexin-induced apoptosis: the key role of the seven-transmembrane domain orexin type 2 receptor.
    Voisin T; Firar AE; Avondo V; Laburthe M
    Endocrinology; 2006 Oct; 147(10):4977-84. PubMed ID: 16857748
    [TBL] [Abstract][Full Text] [Related]  

  • 27. OX1 orexin/hypocretin receptor activation of phospholipase D.
    Jäntti MH; Putula J; Somerharju P; Frohman MA; Kukkonen JP
    Br J Pharmacol; 2012 Feb; 165(4b):1109-23. PubMed ID: 21718304
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Discovery of [(2R,5R)-5-{[(5-fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): a dual orexin receptor antagonist with potent sleep-promoting properties.
    Coleman PJ; Schreier JD; Cox CD; Breslin MJ; Whitman DB; Bogusky MJ; McGaughey GB; Bednar RA; Lemaire W; Doran SM; Fox SV; Garson SL; Gotter AL; Harrell CM; Reiss DR; Cabalu TD; Cui D; Prueksaritanont T; Stevens J; Tannenbaum PL; Ball RG; Stellabott J; Young SD; Hartman GD; Winrow CJ; Renger JJ
    ChemMedChem; 2012 Mar; 7(3):415-24, 337. PubMed ID: 22307992
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Intramolecular fluorescence resonance energy transfer (FRET) sensors of the orexin OX1 and OX2 receptors identify slow kinetics of agonist activation.
    Xu TR; Ward RJ; Pediani JD; Milligan G
    J Biol Chem; 2012 Apr; 287(18):14937-49. PubMed ID: 22389503
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The hypocretins are weak agonists at recombinant human orexin-1 and orexin-2 receptors.
    Smart D; Jerman JC; Brough SJ; Neville WA; Jewitt F; Porter RA
    Br J Pharmacol; 2000 Apr; 129(7):1289-91. PubMed ID: 10742282
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Autocrine endocannabinoid signaling through CB1 receptors potentiates OX1 orexin receptor signaling.
    Jäntti MH; Putula J; Turunen PM; Näsman J; Reijonen S; Lindqvist C; Kukkonen JP
    Mol Pharmacol; 2013 Mar; 83(3):621-32. PubMed ID: 23233488
    [TBL] [Abstract][Full Text] [Related]  

  • 32. OX1 orexin/hypocretin receptor signaling through arachidonic acid and endocannabinoid release.
    Turunen PM; Jäntti MH; Kukkonen JP
    Mol Pharmacol; 2012 Aug; 82(2):156-67. PubMed ID: 22550093
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Rapid identification of orexin receptor binding ligands using cell-based screening accelerated with magnetic beads.
    Qi X; Astle J; Kodadek T
    Mol Biosyst; 2010 Jan; 6(1):102-7. PubMed ID: 20024071
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Pharmacological characterisation of the orexin receptor subtype mediating postsynaptic excitation in the rat dorsal raphe nucleus.
    Soffin EM; Gill CH; Brough SJ; Jerman JC; Davies CH
    Neuropharmacology; 2004 Jun; 46(8):1168-76. PubMed ID: 15111023
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Orexin receptor antagonists: a new concept in CNS disorders?
    Gatfield J; Brisbare-Roch C; Jenck F; Boss C
    ChemMedChem; 2010 Aug; 5(8):1197-214. PubMed ID: 20544785
    [No Abstract]   [Full Text] [Related]  

  • 36. Orexins stimulate glucocorticoid secretion from cultured rat and human adrenocortical cells, exclusively acting via the OX1 receptor.
    Ziolkowska A; Spinazzi R; Albertin G; Nowak M; Malendowicz LK; Tortorella C; Nussdorfer GG
    J Steroid Biochem Mol Biol; 2005 Sep; 96(5):423-9. PubMed ID: 16157481
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Modulation of nociceptive dural input to the trigeminal nucleus caudalis via activation of the orexin 1 receptor in the rat.
    Holland PR; Akerman S; Goadsby PJ
    Eur J Neurosci; 2006 Nov; 24(10):2825-33. PubMed ID: 17156207
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The orexin OX(1) receptor exists predominantly as a homodimer in the basal state: potential regulation of receptor organization by both agonist and antagonist ligands.
    Xu TR; Ward RJ; Pediani JD; Milligan G
    Biochem J; 2011 Oct; 439(1):171-83. PubMed ID: 21770891
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Novel pyrazolo-tetrahydropyridines as potent orexin receptor antagonists.
    Sifferlen T; Boss C; Cottreel E; Koberstein R; Gude M; Aissaoui H; Weller T; Gatfield J; Brisbare-Roch C; Jenck F
    Bioorg Med Chem Lett; 2010 Mar; 20(5):1539-42. PubMed ID: 20144866
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Chimeric, mutant orexin receptors show key interactions between orexin receptors, peptides and antagonists.
    Tran DT; Bonaventure P; Hack M; Mirzadegan T; Dvorak C; Letavic M; Carruthers N; Lovenberg T; Sutton SW
    Eur J Pharmacol; 2011 Sep; 667(1-3):120-8. PubMed ID: 21679703
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.