BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

392 related articles for article (PubMed ID: 22799889)

  • 1. Small molecule activators of the heat shock response: chemical properties, molecular targets, and therapeutic promise.
    West JD; Wang Y; Morano KA
    Chem Res Toxicol; 2012 Oct; 25(10):2036-53. PubMed ID: 22799889
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Underlying mechanisms and chemical/biochemical therapeutic approaches to ameliorate protein misfolding neurodegenerative diseases.
    Hekmatimoghaddam S; Zare-Khormizi MR; Pourrajab F
    Biofactors; 2017 Nov; 43(6):737-759. PubMed ID: 26899445
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The heat shock response and small molecule regulators.
    Kurop MK; Huyen CM; Kelly JH; Blagg BSJ
    Eur J Med Chem; 2021 Dec; 226():113846. PubMed ID: 34563965
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transportable, Chemical Genetic Methodology for the Small Molecule-Mediated Inhibition of Heat Shock Factor 1.
    Moore CL; Dewal MB; Nekongo EE; Santiago S; Lu NB; Levine SS; Shoulders MD
    ACS Chem Biol; 2016 Jan; 11(1):200-10. PubMed ID: 26502114
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The heat-shock response: regulation and function of heat-shock proteins and molecular chaperones.
    Morimoto RI; Kline MP; Bimston DN; Cotto JJ
    Essays Biochem; 1997; 32():17-29. PubMed ID: 9493008
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Contesting the dogma of an age-related heat shock response impairment: implications for cardiac-specific age-related disorders.
    Carnemolla A; Labbadia JP; Lazell H; Neueder A; Moussaoui S; Bates GP
    Hum Mol Genet; 2014 Jul; 23(14):3641-56. PubMed ID: 24556212
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A minimal titration model of the mammalian dynamical heat shock response.
    Sivéry A; Courtade E; Thommen Q
    Phys Biol; 2016 Dec; 13(6):066008. PubMed ID: 27926536
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The functions and regulation of heat shock proteins; key orchestrators of proteostasis and the heat shock response.
    Lang BJ; Guerrero ME; Prince TL; Okusha Y; Bonorino C; Calderwood SK
    Arch Toxicol; 2021 Jun; 95(6):1943-1970. PubMed ID: 34003342
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of heat shock transcription factor 1 as a therapeutic target for small molecule intervention in neurodegenerative disease.
    Neef DW; Turski ML; Thiele DJ
    PLoS Biol; 2010 Jan; 8(1):e1000291. PubMed ID: 20098725
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Shock and awe: unleashing the heat shock response to treat Huntington disease.
    Jackrel ME; Shorter J
    J Clin Invest; 2011 Aug; 121(8):2972-5. PubMed ID: 21785212
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The heat shock response: systems biology of proteotoxic stress in aging and disease.
    Morimoto RI
    Cold Spring Harb Symp Quant Biol; 2011; 76():91-9. PubMed ID: 22371371
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Small-molecule proteostasis regulators for protein conformational diseases.
    Calamini B; Silva MC; Madoux F; Hutt DM; Khanna S; Chalfant MA; Saldanha SA; Hodder P; Tait BD; Garza D; Balch WE; Morimoto RI
    Nat Chem Biol; 2011 Dec; 8(2):185-96. PubMed ID: 22198733
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recent developments in targeting protein misfolding diseases.
    Denny RA; Gavrin LK; Saiah E
    Bioorg Med Chem Lett; 2013 Apr; 23(7):1935-44. PubMed ID: 23454013
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases.
    Neef DW; Jaeger AM; Thiele DJ
    Nat Rev Drug Discov; 2011 Dec; 10(12):930-44. PubMed ID: 22129991
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The cytosolic protein response as a subcomponent of the wider heat shock response in Arabidopsis.
    Sugio A; Dreos R; Aparicio F; Maule AJ
    Plant Cell; 2009 Feb; 21(2):642-54. PubMed ID: 19244141
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of the Hsf1-dependent transcriptome via conserved bipartite contacts with Hsp70 promotes survival in yeast.
    Peffer S; Gonçalves D; Morano KA
    J Biol Chem; 2019 Aug; 294(32):12191-12202. PubMed ID: 31239354
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumor cell survival.
    Vilaboa N; Boré A; Martin-Saavedra F; Bayford M; Winfield N; Firth-Clark S; Kirton SB; Voellmy R
    Nucleic Acids Res; 2017 Jun; 45(10):5797-5817. PubMed ID: 28369544
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Heat shock factor 2 is required for maintaining proteostasis against febrile-range thermal stress and polyglutamine aggregation.
    Shinkawa T; Tan K; Fujimoto M; Hayashida N; Yamamoto K; Takaki E; Takii R; Prakasam R; Inouye S; Mezger V; Nakai A
    Mol Biol Cell; 2011 Oct; 22(19):3571-83. PubMed ID: 21813737
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Heat shock response activation exacerbates inclusion body formation in a cellular model of Huntington disease.
    Bersuker K; Hipp MS; Calamini B; Morimoto RI; Kopito RR
    J Biol Chem; 2013 Aug; 288(33):23633-8. PubMed ID: 23839939
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HSF transcription factor family, heat shock response, and protein intrinsic disorder.
    Westerheide SD; Raynes R; Powell C; Xue B; Uversky VN
    Curr Protein Pept Sci; 2012 Feb; 13(1):86-103. PubMed ID: 22044151
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.