BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 22813531)

  • 1. Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro.
    Preuss J; Maloney P; Peddibhotla S; Hedrick MP; Hershberger P; Gosalia P; Milewski M; Li YL; Sugarman E; Hood B; Suyama E; Nguyen K; Vasile S; Sergienko E; Mangravita-Novo A; Vicchiarelli M; McAnally D; Smith LH; Roth GP; Diwan J; Chung TD; Jortzik E; Rahlfs S; Becker K; Pinkerton AB; Bode L
    J Med Chem; 2012 Aug; 55(16):7262-72. PubMed ID: 22813531
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High-throughput screening for small-molecule inhibitors of plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase.
    Preuss J; Hedrick M; Sergienko E; Pinkerton A; Mangravita-Novo A; Smith L; Marx C; Fischer E; Jortzik E; Rahlfs S; Becker K; Bode L
    J Biomol Screen; 2012 Jul; 17(6):738-51. PubMed ID: 22496096
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase is a potential drug target.
    Allen SM; Lim EE; Jortzik E; Preuss J; Chua HH; MacRae JI; Rahlfs S; Haeussler K; Downton MT; McConville MJ; Becker K; Ralph SA
    FEBS J; 2015 Oct; 282(19):3808-23. PubMed ID: 26198663
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glucose 6-phosphate dehydrogenase 6-phosphogluconolactonase: characterization of the Plasmodium vivax enzyme and inhibitor studies.
    Haeussler K; Berneburg I; Jortzik E; Hahn J; Rahbari M; Schulz N; Preuss J; Zapol'skii VA; Bode L; Pinkerton AB; Kaufmann DE; Rahlfs S; Becker K
    Malar J; 2019 Jan; 18(1):22. PubMed ID: 30683097
    [TBL] [Abstract][Full Text] [Related]  

  • 5. First homology model of Plasmodium falciparum glucose-6-phosphate dehydrogenase: Discovery of selective substrate analog-based inhibitors as novel antimalarial agents.
    Alencar N; Sola I; Linares M; Juárez-Jiménez J; Pont C; Viayna A; Vílchez D; Sampedro C; Abad P; Pérez-Benavente S; Lameira J; Bautista JM; Muñoz-Torrero D; Luque FJ
    Eur J Med Chem; 2018 Feb; 146():108-122. PubMed ID: 29407943
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An Optimized Dihydrodibenzothiazepine Lead Compound (SBI-0797750) as a Potent and Selective Inhibitor of Plasmodium falciparum and P. vivax Glucose 6-Phosphate Dehydrogenase 6-Phosphogluconolactonase.
    Berneburg I; Peddibhotla S; Heimsch KC; Haeussler K; Maloney P; Gosalia P; Preuss J; Rahbari M; Skorokhod O; Valente E; Ulliers D; Simula LF; Buchholz K; Hedrick MP; Hershberger P; Chung TDY; Jackson MR; Schwarzer E; Rahlfs S; Bode L; Becker K; Pinkerton AB
    Antimicrob Agents Chemother; 2022 Apr; 66(4):e0210921. PubMed ID: 35266827
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase: a unique bifunctional enzyme from Plasmodium falciparum.
    Jortzik E; Mailu BM; Preuss J; Fischer M; Bode L; Rahlfs S; Becker K
    Biochem J; 2011 Jun; 436(3):641-50. PubMed ID: 21443518
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of Plasmodium falciparum G6PD-6PGL in laboratory parasites and in patient isolates in G6PD-deficient and normal Nigerian children.
    Sodeinde O; Clarke JL; Vulliamy TJ; Luzzatto L; Mason PJ
    Br J Haematol; 2003 Aug; 122(4):662-8. PubMed ID: 12899722
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Classification of Plasmodium falciparum glucose-6-phosphate dehydrogenase inhibitors by support vector machine.
    Hou X; Yan A
    Mol Divers; 2013 Aug; 17(3):489-97. PubMed ID: 23653283
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transient silencing of Plasmodium falciparum bifunctional glucose-6-phosphate dehydrogenase- 6-phosphogluconolactonase.
    Crooke A; Diez A; Mason PJ; Bautista JM
    FEBS J; 2006 Apr; 273(7):1537-46. PubMed ID: 16689939
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
    Pidathala C; Amewu R; Pacorel B; Nixon GL; Gibbons P; Hong WD; Leung SC; Berry NG; Sharma R; Stocks PA; Srivastava A; Shone AE; Charoensutthivarakul S; Taylor L; Berger O; Mbekeani A; Hill A; Fisher NE; Warman AJ; Biagini GA; Ward SA; O'Neill PM
    J Med Chem; 2012 Mar; 55(5):1831-43. PubMed ID: 22364416
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glucose-6-phosphate metabolism in Plasmodium falciparum.
    Preuss J; Jortzik E; Becker K
    IUBMB Life; 2012 Jul; 64(7):603-11. PubMed ID: 22639416
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The effect and mechanism of inhibiting glucose-6-phosphate dehydrogenase activity on the proliferation of Plasmodium falciparum.
    Zhang Z; Chen X; Jiang C; Fang Z; Feng Y; Jiang W
    Biochim Biophys Acta Mol Cell Res; 2017 May; 1864(5):771-781. PubMed ID: 28214533
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of Novel Plasmodium falciparum Hexokinase Inhibitors with Antiparasitic Activity.
    Davis MI; Patrick SL; Blanding WM; Dwivedi V; Suryadi J; Golden JE; Coussens NP; Lee OW; Shen M; Boxer MB; Hall MD; Sharlow ER; Drew ME; Morris JC
    Antimicrob Agents Chemother; 2016 Oct; 60(10):6023-33. PubMed ID: 27458230
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase. A novel bifunctional enzyme in malaria parasites.
    Clarke JL; Scopes DA; Sodeinde O; Mason PJ
    Eur J Biochem; 2001 Apr; 268(7):2013-9. PubMed ID: 11277923
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pathways for the reduction of oxidized glutathione in the Plasmodium falciparum-infected erythrocyte: can parasite enzymes replace host red cell glucose-6-phosphate dehydrogenase?
    Roth EF; Schulman S; Vanderberg J; Olson J
    Blood; 1986 Mar; 67(3):827-30. PubMed ID: 3511989
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Plasmodium falciparum dihydroorotate dehydrogenase: a drug target against malaria.
    Hoelz LV; Calil FA; Nonato MC; Pinheiro LC; Boechat N
    Future Med Chem; 2018 Aug; 10(15):1853-1874. PubMed ID: 30019917
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A unique insertion in Plasmodium berghei glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase: evolutionary and functional studies.
    Clarke JL; Sodeinde O; Mason PJ
    Mol Biochem Parasitol; 2003 Mar; 127(1):1-8. PubMed ID: 12615331
    [TBL] [Abstract][Full Text] [Related]  

  • 19.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 9.