296 related articles for article (PubMed ID: 22817723)
1. Insulin and IGF-1 signalling: longevity, protein homoeostasis and Alzheimer's disease.
O'Neill C; Kiely AP; Coakley MF; Manning S; Long-Smith CM
Biochem Soc Trans; 2012 Aug; 40(4):721-7. PubMed ID: 22817723
[TBL] [Abstract][Full Text] [Related]
2. PI3-kinase/Akt/mTOR signaling: impaired on/off switches in aging, cognitive decline and Alzheimer's disease.
O' Neill C
Exp Gerontol; 2013 Jul; 48(7):647-53. PubMed ID: 23470275
[TBL] [Abstract][Full Text] [Related]
3. Blockade of the insulin-like growth factor I receptor in the choroid plexus originates Alzheimer's-like neuropathology in rodents: new cues into the human disease?
Carro E; Trejo JL; Spuch C; Bohl D; Heard JM; Torres-Aleman I
Neurobiol Aging; 2006 Nov; 27(11):1618-31. PubMed ID: 16274856
[TBL] [Abstract][Full Text] [Related]
4. Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease.
Freude S; Hettich MM; Schumann C; Stöhr O; Koch L; Köhler C; Udelhoven M; Leeser U; Müller M; Kubota N; Kadowaki T; Krone W; Schröder H; Brüning JC; Schubert M
FASEB J; 2009 Oct; 23(10):3315-24. PubMed ID: 19487308
[TBL] [Abstract][Full Text] [Related]
5. Mammalian target of rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimer's disease?
Cai Z; Zhao B; Li K; Zhang L; Li C; Quazi SH; Tan Y
J Neurosci Res; 2012 Jun; 90(6):1105-18. PubMed ID: 22344941
[TBL] [Abstract][Full Text] [Related]
6. Differential involvement of insulin receptor substrate (IRS)-1 and IRS-2 in brain insulin signaling is associated with the effects on amyloid pathology in a mouse model of Alzheimer's disease.
Ochiai T; Sano T; Nagayama T; Kubota N; Kadowaki T; Wakabayashi T; Iwatsubo T
Neurobiol Dis; 2021 Nov; 159():105510. PubMed ID: 34537327
[TBL] [Abstract][Full Text] [Related]
7. Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD.
Tramutola A; Triplett JC; Di Domenico F; Niedowicz DM; Murphy MP; Coccia R; Perluigi M; Butterfield DA
J Neurochem; 2015 Jun; 133(5):739-49. PubMed ID: 25645581
[TBL] [Abstract][Full Text] [Related]
8. Effects of the superoxide dismutase/catalase mimetic EUK-207 in a mouse model of Alzheimer's disease: protection against and interruption of progression of amyloid and tau pathology and cognitive decline.
Clausen A; Xu X; Bi X; Baudry M
J Alzheimers Dis; 2012; 30(1):183-208. PubMed ID: 22406441
[TBL] [Abstract][Full Text] [Related]
9. Central insulin and insulin-like growth factor-1 signaling: implications for diabetes associated dementia.
Zemva J; Schubert M
Curr Diabetes Rev; 2011 Sep; 7(5):356-66. PubMed ID: 21916834
[TBL] [Abstract][Full Text] [Related]
10. The role of neuronal insulin/insulin-like growth factor-1 signaling for the pathogenesis of Alzheimer's disease: possible therapeutic implications.
Zemva J; Schubert M
CNS Neurol Disord Drug Targets; 2014 Mar; 13(2):322-37. PubMed ID: 24059318
[TBL] [Abstract][Full Text] [Related]
11. High dietary consumption of trans fatty acids decreases brain docosahexaenoic acid but does not alter amyloid-beta and tau pathologies in the 3xTg-AD model of Alzheimer's disease.
Phivilay A; Julien C; Tremblay C; Berthiaume L; Julien P; Giguère Y; Calon F
Neuroscience; 2009 Mar; 159(1):296-307. PubMed ID: 19135506
[TBL] [Abstract][Full Text] [Related]
12. Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease.
Guo JP; Arai T; Miklossy J; McGeer PL
Proc Natl Acad Sci U S A; 2006 Feb; 103(6):1953-8. PubMed ID: 16446437
[TBL] [Abstract][Full Text] [Related]
13. Accumulated amyloid-beta peptide and hyperphosphorylated tau protein: relationship and links in Alzheimer's disease.
Huang HC; Jiang ZF
J Alzheimers Dis; 2009; 16(1):15-27. PubMed ID: 19158417
[TBL] [Abstract][Full Text] [Related]
14. Amyloid precursor protein cytoplasmic domain with phospho-Thr668 accumulates in Alzheimer's disease and its transgenic models: a role to mediate interaction of Abeta and tau.
Shin RW; Ogino K; Shimabuku A; Taki T; Nakashima H; Ishihara T; Kitamoto T
Acta Neuropathol; 2007 Jun; 113(6):627-36. PubMed ID: 17431643
[TBL] [Abstract][Full Text] [Related]
15. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease.
Ho L; Qin W; Pompl PN; Xiang Z; Wang J; Zhao Z; Peng Y; Cambareri G; Rocher A; Mobbs CV; Hof PR; Pasinetti GM
FASEB J; 2004 May; 18(7):902-4. PubMed ID: 15033922
[TBL] [Abstract][Full Text] [Related]
16. The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of Alzheimer's disease: from model organisms to human disease.
Freude S; Schilbach K; Schubert M
Curr Alzheimer Res; 2009 Jun; 6(3):213-23. PubMed ID: 19519303
[TBL] [Abstract][Full Text] [Related]
17. Memantine protects rat cortical cultured neurons against beta-amyloid-induced toxicity by attenuating tau phosphorylation.
Song MS; Rauw G; Baker GB; Kar S
Eur J Neurosci; 2008 Nov; 28(10):1989-2002. PubMed ID: 19046381
[TBL] [Abstract][Full Text] [Related]
18. Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
Batty IH; Fleming IN; Downes CP
Biochem J; 2004 May; 379(Pt 3):641-51. PubMed ID: 14769130
[TBL] [Abstract][Full Text] [Related]
19. Contributions of brain insulin resistance and deficiency in amyloid-related neurodegeneration in Alzheimer's disease.
de la Monte SM
Drugs; 2012 Jan; 72(1):49-66. PubMed ID: 22191795
[TBL] [Abstract][Full Text] [Related]
20. Oxidative balance in Alzheimer's disease: relationship to APOE, Braak tangle stage, and the concentrations of soluble and insoluble amyloid-β.
Tayler H; Fraser T; Miners JS; Kehoe PG; Love S
J Alzheimers Dis; 2010; 22(4):1363-73. PubMed ID: 20930272
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]