BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

580 related articles for article (PubMed ID: 22819776)

  • 1. Mutant SOD1G93A triggers mitochondrial fragmentation in spinal cord motor neurons: neuroprotection by SIRT3 and PGC-1α.
    Song W; Song Y; Kincaid B; Bossy B; Bossy-Wetzel E
    Neurobiol Dis; 2013 Mar; 51():72-81. PubMed ID: 22819776
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ALS-associated mutation SOD1
    Wang H; Yi J; Li X; Xiao Y; Dhakal K; Zhou J
    Bone; 2018 Jan; 106():126-138. PubMed ID: 29030231
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Defective mitochondrial dynamics is an early event in skeletal muscle of an amyotrophic lateral sclerosis mouse model.
    Luo G; Yi J; Ma C; Xiao Y; Yi F; Yu T; Zhou J
    PLoS One; 2013; 8(12):e82112. PubMed ID: 24324755
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial dynamics and bioenergetic dysfunction is associated with synaptic alterations in mutant SOD1 motor neurons.
    Magrané J; Sahawneh MA; Przedborski S; Estévez ÁG; Manfredi G
    J Neurosci; 2012 Jan; 32(1):229-42. PubMed ID: 22219285
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Milanese M; Giribaldi F; Melone M; Bonifacino T; Musante I; Carminati E; Rossi PI; Vergani L; Voci A; Conti F; Puliti A; Bonanno G
    Neurobiol Dis; 2014 Apr; 64():48-59. PubMed ID: 24361555
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants.
    Cassina P; Cassina A; Pehar M; Castellanos R; Gandelman M; de León A; Robinson KM; Mason RP; Beckman JS; Barbeito L; Radi R
    J Neurosci; 2008 Apr; 28(16):4115-22. PubMed ID: 18417691
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amyotrophic lateral sclerosis-associated mutant SOD1 inhibits anterograde axonal transport of mitochondria by reducing Miro1 levels.
    Moller A; Bauer CS; Cohen RN; Webster CP; De Vos KJ
    Hum Mol Genet; 2017 Dec; 26(23):4668-4679. PubMed ID: 28973175
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Vascular endothelial growth factor prevents G93A-SOD1-induced motor neuron degeneration.
    Lunn JS; Sakowski SA; Kim B; Rosenberg AA; Feldman EL
    Dev Neurobiol; 2009 Nov; 69(13):871-84. PubMed ID: 19672955
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glycine receptor channels in spinal motoneurons are abnormal in a transgenic mouse model of amyotrophic lateral sclerosis.
    Chang Q; Martin LJ
    J Neurosci; 2011 Feb; 31(8):2815-27. PubMed ID: 21414903
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aggregates of mutant protein appear progressively in dendrites, in periaxonal processes of oligodendrocytes, and in neuronal and astrocytic perikarya of mice expressing the SOD1(G93A) mutation of familial amyotrophic lateral sclerosis.
    Stieber A; Gonatas JO; Gonatas NK
    J Neurol Sci; 2000 Aug; 177(2):114-23. PubMed ID: 10980307
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: mechanistic relationship and differential sensitivity to intervention.
    Tradewell ML; Cooper LA; Minotti S; Durham HD
    Neurobiol Dis; 2011 Jun; 42(3):265-75. PubMed ID: 21296666
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Arctigenin derivative A-1 ameliorates motor dysfunction and pathological manifestations in SOD1
    Xiong B; Yang C; Yang X; Luo S; Li S; Chen C; He K; Nie L; Li P; Li S; Huang H; Liu J; Zhang Z; Xie Y; Zou L; Yang X
    CNS Neurosci Ther; 2024 Jun; 30(6):e14692. PubMed ID: 38872258
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Abnormal mitochondrial transport and morphology are common pathological denominators in SOD1 and TDP43 ALS mouse models.
    Magrané J; Cortez C; Gan WB; Manfredi G
    Hum Mol Genet; 2014 Mar; 23(6):1413-24. PubMed ID: 24154542
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutant SOD1 in neuronal mitochondria causes toxicity and mitochondrial dynamics abnormalities.
    Magrané J; Hervias I; Henning MS; Damiano M; Kawamata H; Manfredi G
    Hum Mol Genet; 2009 Dec; 18(23):4552-64. PubMed ID: 19779023
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytochrome c association with the inner mitochondrial membrane is impaired in the CNS of G93A-SOD1 mice.
    Kirkinezos IG; Bacman SR; Hernandez D; Oca-Cossio J; Arias LJ; Perez-Pinzon MA; Bradley WG; Moraes CT
    J Neurosci; 2005 Jan; 25(1):164-72. PubMed ID: 15634778
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dismutase-competent SOD1 mutant accumulation in myelinating Schwann cells is not detrimental to normal or transgenic ALS model mice.
    Turner BJ; Ackerley S; Davies KE; Talbot K
    Hum Mol Genet; 2010 Mar; 19(5):815-24. PubMed ID: 20008901
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex.
    Thomsen GM; Gowing G; Latter J; Chen M; Vit JP; Staggenborg K; Avalos P; Alkaslasi M; Ferraiuolo L; Likhite S; Kaspar BK; Svendsen CN
    J Neurosci; 2014 Nov; 34(47):15587-600. PubMed ID: 25411487
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content.
    De Vos KJ; Chapman AL; Tennant ME; Manser C; Tudor EL; Lau KF; Brownlees J; Ackerley S; Shaw PJ; McLoughlin DM; Shaw CE; Leigh PN; Miller CCJ; Grierson AJ
    Hum Mol Genet; 2007 Nov; 16(22):2720-2728. PubMed ID: 17725983
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival.
    Liu R; Li B; Flanagan SW; Oberley LW; Gozal D; Qiu M
    J Neurochem; 2002 Feb; 80(3):488-500. PubMed ID: 11905995
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.