BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 22820662)

  • 1. Low frequency of HIF-1α overexpression in germ cell tumors of the testis.
    Vranic S; Hes O; Grossmann P; Gatalica Z
    Appl Immunohistochem Mol Morphol; 2013 Mar; 21(2):165-9. PubMed ID: 22820662
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Immunoexpression patterns for Hypoxia-inducible Factor-1α and von Hippel-Lindau protein, in relation to Hsp90, of human brain tumors.
    Assimakopoulou M; Androutsopoulou C; Zolota V; Matsoukas J
    Histol Histopathol; 2016 May; 31(5):535-46. PubMed ID: 26592496
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.
    Osada R; Horiuchi A; Kikuchi N; Yoshida J; Hayashi A; Ota M; Katsuyama Y; Melillo G; Konishi I
    Hum Pathol; 2007 Sep; 38(9):1310-20. PubMed ID: 17555795
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Endolymphatic sac tumors in patients with and without von Hippel-Lindau disease: the role of genetic mutation, von Hippel-Lindau protein, and hypoxia inducible factor-1alpha expression.
    Jensen RL; Gillespie D; House P; Layfield L; Shelton C
    J Neurosurg; 2004 Mar; 100(3):488-97. PubMed ID: 15035285
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions.
    Jung YS; Lee SJ; Yoon MH; Ha NC; Park BJ
    Cell Cycle; 2012 Dec; 11(23):4462-73. PubMed ID: 23159849
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
    Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA; Ashcroft M
    Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ηypoxia-inducible factor-1α, von Hippel-Lindau protein, and heat shock protein expression in ophthalmic pterygium and normal conjunctiva.
    Pagoulatos D; Pharmakakis N; Lakoumentas J; Assimakopoulou M
    Mol Vis; 2014; 20():441-57. PubMed ID: 24715760
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.
    Wiesener MS; Münchenhagen PM; Berger I; Morgan NV; Roigas J; Schwiertz A; Jürgensen JS; Gruber G; Maxwell PH; Löning SA; Frei U; Maher ER; Gröne HJ; Eckardt KU
    Cancer Res; 2001 Jul; 61(13):5215-22. PubMed ID: 11431362
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia-inducible factor 1α mediates the down-regulation of superoxide dismutase 2 in von Hippel-Lindau deficient renal clear cell carcinoma.
    Gao YH; Li CX; Shen SM; Li H; Chen GQ; Wei Q; Wang LS
    Biochem Biophys Res Commun; 2013 May; 435(1):46-51. PubMed ID: 23611775
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease.
    Zatyka M; da Silva NF; Clifford SC; Morris MR; Wiesener MS; Eckardt KU; Houlston RS; Richards FM; Latif F; Maher ER
    Cancer Res; 2002 Jul; 62(13):3803-11. PubMed ID: 12097293
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of VHL and HIF-1α and Their Clinicopathologic Significance in Benign and Malignant Lesions of the Gallbladder.
    Yang Z; Yang Z; Xiong L; Huang S; Liu J; Yang L; Miao X
    Appl Immunohistochem Mol Morphol; 2011 Dec; 19(6):534-9. PubMed ID: 21415706
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Over-expression of hypoxia-inducible factor 1 alpha in ovarian clear cell carcinoma.
    Lee S; Garner EI; Welch WR; Berkowitz RS; Mok SC
    Gynecol Oncol; 2007 Aug; 106(2):311-7. PubMed ID: 17532031
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate.
    Merlo A; Bernardo-Castiñeira C; Sáenz-de-Santa-María I; Pitiot AS; Balbín M; Astudillo A; Valdés N; Scola B; Del Toro R; Méndez-Ferrer S; Piruat JI; Suarez C; Chiara MD
    Oncotarget; 2017 Jan; 8(4):6700-6717. PubMed ID: 28036268
    [TBL] [Abstract][Full Text] [Related]  

  • 15. STAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitination.
    Jung JE; Kim HS; Lee CS; Shin YJ; Kim YN; Kang GH; Kim TY; Juhnn YS; Kim SJ; Park JW; Ye SK; Chung MH
    Exp Mol Med; 2008 Oct; 40(5):479-85. PubMed ID: 18985005
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regression of solid tumors by engineered overexpression of von Hippel-Lindau tumor suppressor protein and antisense hypoxia-inducible factor-1alpha.
    Sun X; Kanwar JR; Leung E; Vale M; Krissansen GW
    Gene Ther; 2003 Dec; 10(25):2081-9. PubMed ID: 14595381
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Histone deacetylase inhibitor induced pVHL-independent degradation of HIF-1α and hierarchical quality control of pVHL via chaperone system.
    Ni J; Ni A
    PLoS One; 2021; 16(7):e0248019. PubMed ID: 34329303
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of point mutations in pVHL on the binding of HIF-1α.
    Domene C; Illingworth CJ
    Proteins; 2012 Mar; 80(3):733-46. PubMed ID: 22105711
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of somatic VHL gene mutations in sporadic head and neck paragangliomas in association with activation of the HIF-1α/miR-210 signaling pathway.
    Merlo A; de Quirós SB; de Santa-María IS; Pitiot AS; Balbín M; Astudillo A; Scola B; Arístegui M; Quer M; Suarez C; Chiara MD
    J Clin Endocrinol Metab; 2013 Oct; 98(10):E1661-6. PubMed ID: 23902947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pancreatic endocrine microadenomatosis in patients with von Hippel-Lindau disease: characterization by VHL/HIF pathway proteins expression.
    Périgny M; Hammel P; Corcos O; Larochelle O; Giraud S; Richard S; Sauvanet A; Belghiti J; Ruszniewski P; Bedossa P; Couvelard A
    Am J Surg Pathol; 2009 May; 33(5):739-48. PubMed ID: 19238077
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.