288 related articles for article (PubMed ID: 22825052)
1. Unidirectional peristaltic movement in multisite drug binding pockets of AcrB from molecular dynamics simulations.
Feng Z; Hou T; Li Y
Mol Biosyst; 2012 Oct; 8(10):2699-709. PubMed ID: 22825052
[TBL] [Abstract][Full Text] [Related]
2. Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket.
Nakashima R; Sakurai K; Yamasaki S; Nishino K; Yamaguchi A
Nature; 2011 Nov; 480(7378):565-9. PubMed ID: 22121023
[TBL] [Abstract][Full Text] [Related]
3. Crystal structures of a multidrug transporter reveal a functionally rotating mechanism.
Murakami S; Nakashima R; Yamashita E; Matsumoto T; Yamaguchi A
Nature; 2006 Sep; 443(7108):173-9. PubMed ID: 16915237
[TBL] [Abstract][Full Text] [Related]
4. Role of water during the extrusion of substrates by the efflux transporter AcrB.
Schulz R; Vargiu AV; Ruggerone P; Kleinekathöfer U
J Phys Chem B; 2011 Jun; 115(25):8278-87. PubMed ID: 21657235
[TBL] [Abstract][Full Text] [Related]
5. Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
Sjuts H; Vargiu AV; Kwasny SM; Nguyen ST; Kim HS; Ding X; Ornik AR; Ruggerone P; Bowlin TL; Nikaido H; Pos KM; Opperman TJ
Proc Natl Acad Sci U S A; 2016 Mar; 113(13):3509-14. PubMed ID: 26976576
[TBL] [Abstract][Full Text] [Related]
6. Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.
Seeger MA; Schiefner A; Eicher T; Verrey F; Diederichs K; Pos KM
Science; 2006 Sep; 313(5791):1295-8. PubMed ID: 16946072
[TBL] [Abstract][Full Text] [Related]
7. New insights into the structural and functional involvement of the gate loop in AcrB export activity.
Ababou A
Biochim Biophys Acta Proteins Proteom; 2018 Feb; 1866(2):242-253. PubMed ID: 29126836
[TBL] [Abstract][Full Text] [Related]
8. Computer simulations suggest direct and stable tip to tip interaction between the outer membrane channel TolC and the isolated docking domain of the multidrug RND efflux transporter AcrB.
Schmidt TH; Raunest M; Fischer N; Reith D; Kandt C
Biochim Biophys Acta; 2016 Jul; 1858(7 Pt A):1419-26. PubMed ID: 27045078
[TBL] [Abstract][Full Text] [Related]
9. Dissecting the function of a protruding loop in AcrB trimerization.
Fang J; Yu L; Wu M; Wei Y
J Biomol Struct Dyn; 2013 Apr; 31(4):385-92. PubMed ID: 22877148
[TBL] [Abstract][Full Text] [Related]
10. Elastic network model-based normal mode analysis reveals the conformational couplings in the tripartite AcrAB-TolC multidrug efflux complex.
Wang B; Weng J; Fan K; Wang W
Proteins; 2011 Oct; 79(10):2936-45. PubMed ID: 21905116
[TBL] [Abstract][Full Text] [Related]
11. Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate.
Ababou A; Koronakis V
PLoS One; 2016; 11(7):e0159154. PubMed ID: 27403665
[TBL] [Abstract][Full Text] [Related]
12. Crystal structure of bacterial multidrug efflux transporter AcrB.
Murakami S; Nakashima R; Yamashita E; Yamaguchi A
Nature; 2002 Oct; 419(6907):587-93. PubMed ID: 12374972
[TBL] [Abstract][Full Text] [Related]
13. Structural basis for the inhibition of bacterial multidrug exporters.
Nakashima R; Sakurai K; Yamasaki S; Hayashi K; Nagata C; Hoshino K; Onodera Y; Nishino K; Yamaguchi A
Nature; 2013 Aug; 500(7460):102-6. PubMed ID: 23812586
[TBL] [Abstract][Full Text] [Related]
14. Substrate-dependent transport mechanism in AcrB of multidrug resistant bacteria.
Jewel Y; Van Dinh Q; Liu J; Dutta P
Proteins; 2020 Jul; 88(7):853-864. PubMed ID: 31998988
[TBL] [Abstract][Full Text] [Related]
15. Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps.
Plé C; Tam HK; Vieira Da Cruz A; Compagne N; Jiménez-Castellanos JC; Müller RT; Pradel E; Foong WE; Malloci G; Ballée A; Kirchner MA; Moshfegh P; Herledan A; Herrmann A; Deprez B; Willand N; Vargiu AV; Pos KM; Flipo M; Hartkoorn RC
Nat Commun; 2022 Jan; 13(1):115. PubMed ID: 35013254
[TBL] [Abstract][Full Text] [Related]
16. Switch-loop flexibility affects transport of large drugs by the promiscuous AcrB multidrug efflux transporter.
Cha HJ; Müller RT; Pos KM
Antimicrob Agents Chemother; 2014 Aug; 58(8):4767-72. PubMed ID: 24914123
[TBL] [Abstract][Full Text] [Related]
17. Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system.
Touzé T; Eswaran J; Bokma E; Koronakis E; Hughes C; Koronakis V
Mol Microbiol; 2004 Jul; 53(2):697-706. PubMed ID: 15228545
[TBL] [Abstract][Full Text] [Related]
18. Reversal of the Drug Binding Pocket Defects of the AcrB Multidrug Efflux Pump Protein of Escherichia coli.
Soparkar K; Kinana AD; Weeks JW; Morrison KD; Nikaido H; Misra R
J Bacteriol; 2015 Oct; 197(20):3255-64. PubMed ID: 26240069
[TBL] [Abstract][Full Text] [Related]
19. Kinetic analysis of the inhibition of the drug efflux protein AcrB using surface plasmon resonance.
Mowla R; Wang Y; Ma S; Venter H
Biochim Biophys Acta Biomembr; 2018 Apr; 1860(4):878-886. PubMed ID: 28890187
[TBL] [Abstract][Full Text] [Related]
20. Structural and functional aspects of the multidrug efflux pump AcrB.
Eicher T; Brandstätter L; Pos KM
Biol Chem; 2009 Aug; 390(8):693-9. PubMed ID: 19453279
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
