185 related articles for article (PubMed ID: 22832492)
1. Inhibition of CRM1-mediated nucleocytoplasmic transport: triggering human melanoma cell apoptosis by perturbing multiple cellular pathways.
Pathria G; Wagner C; Wagner SN
J Invest Dermatol; 2012 Dec; 132(12):2780-90. PubMed ID: 22832492
[TBL] [Abstract][Full Text] [Related]
2. Novel small molecule XPO1/CRM1 inhibitors induce nuclear accumulation of TP53, phosphorylated MAPK and apoptosis in human melanoma cells.
Yang J; Bill MA; Young GS; La Perle K; Landesman Y; Shacham S; Kauffman M; Senapedis W; Kashyap T; Saint-Martin JR; Kendra K; Lesinski GB
PLoS One; 2014; 9(7):e102983. PubMed ID: 25057921
[TBL] [Abstract][Full Text] [Related]
3. Crm1 is a mitotic effector of Ran-GTP in somatic cells.
Arnaoutov A; Azuma Y; Ribbeck K; Joseph J; Boyarchuk Y; Karpova T; McNally J; Dasso M
Nat Cell Biol; 2005 Jun; 7(6):626-32. PubMed ID: 15908946
[TBL] [Abstract][Full Text] [Related]
4. CRM1 and BRAF inhibition synergize and induce tumor regression in BRAF-mutant melanoma.
Salas Fragomeni RA; Chung HW; Landesman Y; Senapedis W; Saint-Martin JR; Tsao H; Flaherty KT; Shacham S; Kauffman M; Cusack JC
Mol Cancer Ther; 2013 Jul; 12(7):1171-9. PubMed ID: 23615632
[TBL] [Abstract][Full Text] [Related]
5. Anti-tumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin.
De Cesare M; Cominetti D; Doldi V; Lopergolo A; Deraco M; Gandellini P; Friedlander S; Landesman Y; Kauffman MG; Shacham S; Pennati M; Zaffaroni N
Oncotarget; 2015 May; 6(15):13119-32. PubMed ID: 25948791
[TBL] [Abstract][Full Text] [Related]
6. The Cellular Distribution of RanGAP1 Is Regulated by CRM1-Mediated Nuclear Export in Mammalian Cells.
Cha K; Sen P; Raghunayakula S; Zhang XD
PLoS One; 2015; 10(10):e0141309. PubMed ID: 26506250
[TBL] [Abstract][Full Text] [Related]
7. Novel reversible selective inhibitor of nuclear export shows that CRM1 is a target in colorectal cancer cells.
Niu M; Chong Y; Han Y; Liu X
Cancer Biol Ther; 2015; 16(7):1110-8. PubMed ID: 25996664
[TBL] [Abstract][Full Text] [Related]
8. Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export.
Lindsay ME; Holaska JM; Welch K; Paschal BM; Macara IG
J Cell Biol; 2001 Jun; 153(7):1391-402. PubMed ID: 11425870
[TBL] [Abstract][Full Text] [Related]
9. CBS9106-induced CRM1 degradation is mediated by cullin ring ligase activity and the neddylation pathway.
Saito N; Sakakibara K; Sato T; Friedman JM; Kufe DW; VonHoff DD; Kawabe T
Mol Cancer Ther; 2014 Dec; 13(12):3013-23. PubMed ID: 25253782
[TBL] [Abstract][Full Text] [Related]
10. Overexpression of CRM1: A Characteristic Feature in a Transformed Phenotype of Lung Carcinogenesis and a Molecular Target for Lung Cancer Adjuvant Therapy.
Gao W; Lu C; Chen L; Keohavong P
J Thorac Oncol; 2015 May; 10(5):815-825. PubMed ID: 25629636
[TBL] [Abstract][Full Text] [Related]
11. CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis.
Connor MK; Kotchetkov R; Cariou S; Resch A; Lupetti R; Beniston RG; Melchior F; Hengst L; Slingerland JM
Mol Biol Cell; 2003 Jan; 14(1):201-13. PubMed ID: 12529437
[TBL] [Abstract][Full Text] [Related]
12. The mobile FG nucleoporin Nup98 is a cofactor for Crm1-dependent protein export.
Oka M; Asally M; Yasuda Y; Ogawa Y; Tachibana T; Yoneda Y
Mol Biol Cell; 2010 Jun; 21(11):1885-96. PubMed ID: 20375145
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins.
Takeda A; Sarma NJ; Abdul-Nabi AM; Yaseen NR
J Biol Chem; 2010 May; 285(21):16248-57. PubMed ID: 20233715
[TBL] [Abstract][Full Text] [Related]
14. Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication.
Wang W; Budhu A; Forgues M; Wang XW
Nat Cell Biol; 2005 Aug; 7(8):823-30. PubMed ID: 16041368
[TBL] [Abstract][Full Text] [Related]
15. A role for Ran-GTP and Crm1 in blocking re-replication.
Yamaguchi R; Newport J
Cell; 2003 Apr; 113(1):115-25. PubMed ID: 12679039
[TBL] [Abstract][Full Text] [Related]
16. Polo-like kinase 1 is a potential therapeutic target in human melanoma.
Jalili A; Moser A; Pashenkov M; Wagner C; Pathria G; Borgdorff V; Gschaider M; Stingl G; Ramaswamy S; Wagner SN
J Invest Dermatol; 2011 Sep; 131(9):1886-95. PubMed ID: 21654832
[TBL] [Abstract][Full Text] [Related]
17. Cardiovirus Leader proteins bind exportins: Implications for virus replication and nucleocytoplasmic trafficking inhibition.
Ciomperlik JJ; Basta HA; Palmenberg AC
Virology; 2016 Jan; 487():19-26. PubMed ID: 26492198
[TBL] [Abstract][Full Text] [Related]
18. The nuclear exporter, Crm1, is regulated by NFY and Sp1 in cancer cells and repressed by p53 in response to DNA damage.
van der Watt PJ; Leaner VD
Biochim Biophys Acta; 2011 Jul; 1809(7):316-26. PubMed ID: 21683812
[TBL] [Abstract][Full Text] [Related]
19. Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Baumhardt JM; Walker JS; Lee Y; Shakya B; Brautigam CA; Lapalombella R; Grishin N; Chook YM
Mol Biol Cell; 2020 Aug; 31(17):1879-1891. PubMed ID: 32520643
[TBL] [Abstract][Full Text] [Related]
20. Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells.
Etchin J; Sun Q; Kentsis A; Farmer A; Zhang ZC; Sanda T; Mansour MR; Barcelo C; McCauley D; Kauffman M; Shacham S; Christie AL; Kung AL; Rodig SJ; Chook YM; Look AT
Leukemia; 2013 Jan; 27(1):66-74. PubMed ID: 22847027
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]