114 related articles for article (PubMed ID: 22833675)
1. Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.
He J; Shi LZ; Truong LN; Lu CS; Razavian N; Li Y; Negrete A; Shiloach J; Berns MW; Wu X
J Biol Chem; 2012 Sep; 287(38):31747-56. PubMed ID: 22833675
[TBL] [Abstract][Full Text] [Related]
2. Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts.
Tatsukawa K; Sakamoto R; Kawasoe Y; Kubota Y; Tsurimoto T; Takahashi TS; Ohashi E
Nucleic Acids Res; 2024 Apr; 52(6):3146-3163. PubMed ID: 38349040
[TBL] [Abstract][Full Text] [Related]
3. Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.
Buis J; Wu Y; Deng Y; Leddon J; Westfield G; Eckersdorff M; Sekiguchi JM; Chang S; Ferguson DO
Cell; 2008 Oct; 135(1):85-96. PubMed ID: 18854157
[TBL] [Abstract][Full Text] [Related]
4. MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends.
Sharma S; Anand R; Zhang X; Francia S; Michelini F; Galbiati A; Williams H; Ronato DA; Masson JY; Rothenberg E; Cejka P; d'Adda di Fagagna F
Cell Rep; 2021 Jan; 34(1):108565. PubMed ID: 33406426
[TBL] [Abstract][Full Text] [Related]
5. The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.
Roset R; Inagaki A; Hohl M; Brenet F; Lafrance-Vanasse J; Lange J; Scandura JM; Tainer JA; Keeney S; Petrini JH
Genes Dev; 2014 Mar; 28(5):451-62. PubMed ID: 24532689
[TBL] [Abstract][Full Text] [Related]
6. [Research Progress in the Roles of MRE11-RAD50-NBS1 Complex and Human Diseases].
Xu XH; Liu YD
Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2024 Apr; 46(2):232-241. PubMed ID: 38686720
[TBL] [Abstract][Full Text] [Related]
7. A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans.
Chansel-Da Cruz M; Hohl M; Ceppi I; Kermasson L; Maggiorella L; Modesti M; de Villartay JP; Ileri T; Cejka P; Petrini JHJ; Revy P
Cell Rep; 2020 Dec; 33(13):108559. PubMed ID: 33378670
[TBL] [Abstract][Full Text] [Related]
8. Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study.
Damiola F; Pertesi M; Oliver J; Le Calvez-Kelm F; Voegele C; Young EL; Robinot N; Forey N; Durand G; Vallée MP; Tao K; Roane TC; Williams GJ; Hopper JL; Southey MC; Andrulis IL; John EM; Goldgar DE; Lesueur F; Tavtigian SV
Breast Cancer Res; 2014 Jun; 16(3):R58. PubMed ID: 24894818
[TBL] [Abstract][Full Text] [Related]
9. Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors.
Hartlerode AJ; Morgan MJ; Wu Y; Buis J; Ferguson DO
Nat Struct Mol Biol; 2015 Sep; 22(9):736-43. PubMed ID: 26280532
[TBL] [Abstract][Full Text] [Related]
10. The MRN complex promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes.
Mehnert AK; Prorocic M; Dujeancourt-Henry A; Hutchinson S; McCulloch R; Glover L
Nucleic Acids Res; 2021 Feb; 49(3):1436-1454. PubMed ID: 33450001
[TBL] [Abstract][Full Text] [Related]
11. The Mre11 complex is required for ATM activation and the G2/M checkpoint.
Carson CT; Schwartz RA; Stracker TH; Lilley CE; Lee DV; Weitzman MD
EMBO J; 2003 Dec; 22(24):6610-20. PubMed ID: 14657032
[TBL] [Abstract][Full Text] [Related]
12. RBBP4 regulates the expression of the Mre11-Rad50-NBS1 (MRN) complex and promotes DNA double-strand break repair to mediate glioblastoma chemoradiotherapy resistance.
Li J; Song C; Gu J; Li C; Zang W; Shi L; Chen L; Zhu L; Zhou M; Wang T; Li H; Qi S; Lu Y
Cancer Lett; 2023 Mar; 557():216078. PubMed ID: 36736531
[TBL] [Abstract][Full Text] [Related]
13. The molecular details of a novel phosphorylation-dependent interaction between MRN and the SOSS complex.
El-Kamand S; Adams MN; Matthews JM; Du Plessis MD; Crossett B; Connolly A; Breen N; Dudley A; Richard DJ; Gamsjaeger R; Cubeddu L
Protein Sci; 2023 Oct; 32(10):e4782. PubMed ID: 37705456
[TBL] [Abstract][Full Text] [Related]
14. Turning the Mre11/Rad50 DNA repair complex on its head: lessons from SMC protein hinges, dynamic coiled-coil movements and DNA loop-extrusion?
Zabolotnaya E; Mela I; Henderson RM; Robinson NP
Biochem Soc Trans; 2020 Dec; 48(6):2359-2376. PubMed ID: 33300987
[TBL] [Abstract][Full Text] [Related]
15. The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.
Syed A; Tainer JA
Annu Rev Biochem; 2018 Jun; 87():263-294. PubMed ID: 29709199
[TBL] [Abstract][Full Text] [Related]
16. Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis.
Hohl M; Mojumdar A; Hailemariam S; Kuryavyi V; Ghisays F; Sorenson K; Chang M; Taylor BS; Patel DJ; Burgers PM; Cobb JA; Petrini JHJ
PLoS Genet; 2020 Mar; 16(3):e1008422. PubMed ID: 32187176
[TBL] [Abstract][Full Text] [Related]
17. ATM directs DNA damage responses and proteostasis via genetically separable pathways.
Lee JH; Mand MR; Kao CH; Zhou Y; Ryu SW; Richards AL; Coon JJ; Paull TT
Sci Signal; 2018 Jan; 11(512):. PubMed ID: 29317520
[TBL] [Abstract][Full Text] [Related]
18. MRE11 stability is regulated by CK2-dependent interaction with R2TP complex.
von Morgen P; Burdova K; Flower TG; O'Reilly NJ; Boulton SJ; Smerdon SJ; Macurek L; Hořejší Z
Oncogene; 2017 Aug; 36(34):4943-4950. PubMed ID: 28436950
[TBL] [Abstract][Full Text] [Related]
19. Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage.
Stracker TH; Couto SS; Cordon-Cardo C; Matos T; Petrini JH
Mol Cell; 2008 Jul; 31(1):21-32. PubMed ID: 18614044
[TBL] [Abstract][Full Text] [Related]
20. USP4 Auto-Deubiquitylation Promotes Homologous Recombination.
Wijnhoven P; Konietzny R; Blackford AN; Travers J; Kessler BM; Nishi R; Jackson SP
Mol Cell; 2015 Nov; 60(3):362-73. PubMed ID: 26455393
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]