BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 22834478)

  • 1. In vitro inhibition and induction of human cytochrome P450 enzymes by mirabegron, a potent and selective β3-adrenoceptor agonist.
    Takusagawa S; Miyashita A; Iwatsubo T; Usui T
    Xenobiotica; 2012 Dec; 42(12):1187-96. PubMed ID: 22834478
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of human cytochrome P450 isoforms and esterases involved in the metabolism of mirabegron, a potent and selective β3-adrenoceptor agonist.
    Takusagawa S; Yajima K; Miyashita A; Uehara S; Iwatsubo T; Usui T
    Xenobiotica; 2012 Oct; 42(10):957-67. PubMed ID: 22509825
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition.
    Sahi J; Black CB; Hamilton GA; Zheng X; Jolley S; Rose KA; Gilbert D; LeCluyse EL; Sinz MW
    Drug Metab Dispos; 2003 Apr; 31(4):439-46. PubMed ID: 12642470
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro assessment of cytochrome P450 inhibition and induction potential of felotaxel (SHR110008).
    Ding Y; Jia Y; Lu C; Liu W; Yang J; Song Y; Zhu Y; Yang L; Ding L; Wen A
    Biomed Pharmacother; 2012 Jun; 66(4):318-21. PubMed ID: 22397757
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An in vitro evaluation of the victim and perpetrator potential of the anticancer agent laromustine (VNP40101M), based on reaction phenotyping and inhibition and induction of cytochrome P450 enzymes.
    Nassar AE; King I; Paris BL; Haupt L; Ndikum-Moffor F; Campbell R; Usuki E; Skibbe J; Brobst D; Ogilvie BW; Parkinson A
    Drug Metab Dispos; 2009 Sep; 37(9):1922-30. PubMed ID: 19520774
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro inhibition and induction of human hepatic cytochrome P450 enzymes by modafinil.
    Robertson P; DeCory HH; Madan A; Parkinson A
    Drug Metab Dispos; 2000 Jun; 28(6):664-71. PubMed ID: 10820139
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mirabegron, a β₃-adrenoceptor agonist for the potential treatment of urinary frequency, urinary incontinence or urgency associated with overactive bladder.
    Tyagi P; Tyagi V
    IDrugs; 2010 Oct; 13(10):713-22. PubMed ID: 20878594
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes.
    Parkinson A; Mudra DR; Johnson C; Dwyer A; Carroll KM
    Toxicol Appl Pharmacol; 2004 Sep; 199(3):193-209. PubMed ID: 15364537
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro studies investigating the interactions between degarelix, a decapeptide gonadotropin-releasing hormone blocker, and cytochrome P450.
    Sonesson A; Rasmussen BB
    Basic Clin Pharmacol Toxicol; 2011 Sep; 109(3):195-202. PubMed ID: 21496210
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro assessment of cytochrome P450 inhibition and induction potential of tanespimycin and its major metabolite, 17-amino-17-demethoxygeldanamycin.
    Gan J; Liu-Kreyche P; Humphreys WG
    Cancer Chemother Pharmacol; 2012 Jan; 69(1):51-6. PubMed ID: 21594721
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of time-dependent cytochrome P450 inhibition using cultured human hepatocytes.
    McGinnity DF; Berry AJ; Kenny JR; Grime K; Riley RJ
    Drug Metab Dispos; 2006 Aug; 34(8):1291-300. PubMed ID: 16679385
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human cytochrome p450 induction and inhibition potential of clevidipine and its primary metabolite h152/81.
    Zhang JG; Dehal SS; Ho T; Johnson J; Chandler C; Blanchard AP; Clark RJ; Crespi CL; Stresser DM; Wong J
    Drug Metab Dispos; 2006 May; 34(5):734-7. PubMed ID: 16501008
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro characterization of the metabolic pathways and cytochrome P450 inhibition and induction potential of BMS-690514, an ErbB/vascular endothelial growth factor receptor inhibitor.
    Hong H; Su H; Ma L; Yao M; Iyer RA; Humphreys WG; Christopher LJ
    Drug Metab Dispos; 2011 Sep; 39(9):1658-67. PubMed ID: 21673131
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vitro inhibition and induction of human liver cytochrome p450 enzymes by milnacipran.
    Paris BL; Ogilvie BW; Scheinkoenig JA; Ndikum-Moffor F; Gibson R; Parkinson A
    Drug Metab Dispos; 2009 Oct; 37(10):2045-54. PubMed ID: 19608694
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Direct and metabolism-dependent cytochrome P450 inhibition assays for evaluating drug-drug interactions.
    Lee KS; Kim SK
    J Appl Toxicol; 2013 Feb; 33(2):100-8. PubMed ID: 21915887
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition and induction of human cytochrome P450 enzymes in vitro by capsaicin.
    Babbar S; Chanda S; Bley K
    Xenobiotica; 2010 Dec; 40(12):807-16. PubMed ID: 20863199
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes.
    Xing J; Kirby BJ; Whittington D; Wan Y; Goodlett DR
    Drug Metab Dispos; 2012 Sep; 40(9):1757-64. PubMed ID: 22679214
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro evaluation of the interaction potential of irosustat with drug-metabolizing enzymes.
    Ventura V; Solà J; Peraire C; Brée F; Obach R
    Drug Metab Dispos; 2012 Jul; 40(7):1268-78. PubMed ID: 22451700
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro evaluation of potential drug-drug interactions with ticagrelor: cytochrome P450 reaction phenotyping, inhibition, induction, and differential kinetics.
    Zhou D; Andersson TB; Grimm SW
    Drug Metab Dispos; 2011 Apr; 39(4):703-10. PubMed ID: 21177984
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Follow-up to the pre-validation of a harmonised protocol for assessment of CYP induction responses in freshly isolated and cryopreserved human hepatocytes with respect to culture format, treatment, positive reference inducers and incubation conditions.
    Abadie-Viollon C; Martin H; Blanchard N; Pekthong D; Bachellier P; Mantion G; Heyd B; Schuler F; Coassolo P; Alexandre E; Richert L
    Toxicol In Vitro; 2010 Feb; 24(1):346-56. PubMed ID: 19497360
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.