BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 22837667)

  • 1. Role of helicity on the anticancer mechanism of action of cationic-helical peptides.
    Huang YB; He LY; Jiang HY; Chen YX
    Int J Mol Sci; 2012; 13(6):6849-6862. PubMed ID: 22837667
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of helicity of α-helical antimicrobial peptides to improve specificity.
    Huang Y; He L; Li G; Zhai N; Jiang H; Chen Y
    Protein Cell; 2014; 5(8):631-42. PubMed ID: 24805306
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index.
    Chen Y; Mant CT; Farmer SW; Hancock RE; Vasil ML; Hodges RS
    J Biol Chem; 2005 Apr; 280(13):12316-29. PubMed ID: 15677462
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of hydrophobicity on the antifungal activity of alpha-helical antimicrobial peptides.
    Jiang Z; Kullberg BJ; van der Lee H; Vasil AI; Hale JD; Mant CT; Hancock RE; Vasil ML; Netea MG; Hodges RS
    Chem Biol Drug Des; 2008 Dec; 72(6):483-95. PubMed ID: 19090916
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enantiomeric Effect of d-Amino Acid Substitution on the Mechanism of Action of α-Helical Membrane-Active Peptides.
    Sun S; Zhao G; Huang Y; Cai M; Yan Q; Wang H; Chen Y
    Int J Mol Sci; 2017 Dec; 19(1):. PubMed ID: 29280948
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects and mechanisms of the secondary structure on the antimicrobial activity and specificity of antimicrobial peptides.
    Mai XT; Huang J; Tan J; Huang Y; Chen Y
    J Pept Sci; 2015 Jul; 21(7):561-8. PubMed ID: 25826179
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides.
    Jiang Z; Vasil AI; Hale JD; Hancock RE; Vasil ML; Hodges RS
    Biopolymers; 2008; 90(3):369-83. PubMed ID: 18098173
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rational design of peptides with anti-HCV/HIV activities and enhanced specificity.
    Li GR; He LY; Liu XY; Liu AP; Huang YB; Qiu C; Zhang XY; Xu JQ; Yang W; Chen YX
    Chem Biol Drug Des; 2011 Nov; 78(5):835-43. PubMed ID: 21801309
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Designing α-helical peptides with enhanced synergism and selectivity against Mycobacterium smegmatis: Discerning the role of hydrophobicity and helicity.
    Khara JS; Lim FK; Wang Y; Ke XY; Voo ZX; Yang YY; Lakshminarayanan R; Ee PLR
    Acta Biomater; 2015 Dec; 28():99-108. PubMed ID: 26380930
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of single amino acid substitution on the biophysical properties and biological activities of an amphipathic α-helical antibacterial peptide against Gram-negative bacteria.
    Tan J; Huang J; Huang Y; Chen Y
    Molecules; 2014 Jul; 19(8):10803-17. PubMed ID: 25061725
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dermaseptin S9, an alpha-helical antimicrobial peptide with a hydrophobic core and cationic termini.
    Lequin O; Ladram A; Chabbert L; Bruston F; Convert O; Vanhoye D; Chassaing G; Nicolas P; Amiche M
    Biochemistry; 2006 Jan; 45(2):468-80. PubMed ID: 16401077
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Studies on mechanism of action of anticancer peptides by modulation of hydrophobicity within a defined structural framework.
    Huang YB; Wang XF; Wang HY; Liu Y; Chen Y
    Mol Cancer Ther; 2011 Mar; 10(3):416-26. PubMed ID: 21252288
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Disruption of interactions between hydrophobic residues on nonpolar faces is a key determinant in decreasing hemolysis and increasing antimicrobial activities of α-helical amphipathic peptides.
    Son M; Lee Y; Hwang H; Hyun S; Yu J
    ChemMedChem; 2013 Oct; 8(10):1638-42. PubMed ID: 23894079
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design of potent, non-toxic anticancer peptides based on the structure of the antimicrobial peptide, temporin-1CEa.
    Yang QZ; Wang C; Lang L; Zhou Y; Wang H; Shang DJ
    Arch Pharm Res; 2013 Nov; 36(11):1302-10. PubMed ID: 23609760
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of residue 5-point mutation and N-terminus hydrophobic residues on temporin-SHc physicochemical and biological properties.
    Abbassi F; Piesse C; Foulon T; Nicolas P; Ladram A
    Mol Cell Biochem; 2014 Sep; 394(1-2):91-9. PubMed ID: 24842084
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides.
    Chen Y; Guarnieri MT; Vasil AI; Vasil ML; Mant CT; Hodges RS
    Antimicrob Agents Chemother; 2007 Apr; 51(4):1398-406. PubMed ID: 17158938
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7.
    Conlon JM; Galadari S; Raza H; Condamine E
    Chem Biol Drug Des; 2008 Jul; 72(1):58-64. PubMed ID: 18554256
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, Synthesis and Anticancer Activity of Site Specific Short Chain Cationic Peptide.
    Sharma RD; Jain J; Khosa RL
    Curr Drug Discov Technol; 2020; 17(5):631-646. PubMed ID: 30947673
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs.
    Shin SY; Lee SH; Yang ST; Park EJ; Lee DG; Lee MK; Eom SH; Song WK; Kim Y; Hahm KS; Kim JI
    J Pept Res; 2001 Dec; 58(6):504-14. PubMed ID: 12005420
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Surface Physical Activity and Hydrophobicity of Designed Helical Peptide Amphiphiles Control Their Bioactivity and Cell Selectivity.
    Chen C; Yang C; Chen Y; Wang F; Mu Q; Zhang J; Li Z; Pan F; Xu H; Lu JR
    ACS Appl Mater Interfaces; 2016 Oct; 8(40):26501-26510. PubMed ID: 27644109
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.