These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 22842046)

  • 1. Flavonoid interactions with human transthyretin: combined structural and thermodynamic analysis.
    Trivella DB; dos Reis CV; Lima LM; Foguel D; Polikarpov I
    J Struct Biol; 2012 Oct; 180(1):143-53. PubMed ID: 22842046
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
    Trivella DB; Bleicher L; Palmieri Lde C; Wiggers HJ; Montanari CA; Kelly JW; Lima LM; Foguel D; Polikarpov I
    J Struct Biol; 2010 Jun; 170(3):522-31. PubMed ID: 20211733
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
    Trivella DB; Sairre MI; Foguel D; Lima LM; Polikarpov I
    J Struct Biol; 2011 Feb; 173(2):323-32. PubMed ID: 20937391
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The crystal structure of the green tea polyphenol (-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site.
    Miyata M; Sato T; Kugimiya M; Sho M; Nakamura T; Ikemizu S; Chirifu M; Mizuguchi M; Nabeshima Y; Suwa Y; Morioka H; Arimori T; Suico MA; Shuto T; Sako Y; Momohara M; Koga T; Morino-Koga S; Yamagata Y; Kai H
    Biochemistry; 2010 Jul; 49(29):6104-14. PubMed ID: 20565072
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin.
    Morais-de-Sá E; Neto-Silva RM; Pereira PJ; Saraiva MJ; Damas AM
    Acta Crystallogr D Biol Crystallogr; 2006 May; 62(Pt 5):512-9. PubMed ID: 16627944
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cys-10 mixed disulfide modifications exacerbate transthyretin familial variant amyloidogenicity: a likely explanation for variable clinical expression of amyloidosis and the lack of pathology in C10S/V30M transgenic mice?
    Zhang Q; Kelly JW
    Biochemistry; 2005 Jun; 44(25):9079-85. PubMed ID: 15966731
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural insight into pH-induced conformational changes within the native human transthyretin tetramer.
    Palaninathan SK; Mohamedmohaideen NN; Snee WC; Kelly JW; Sacchettini JC
    J Mol Biol; 2008 Oct; 382(5):1157-67. PubMed ID: 18662699
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intrinsic versus mutation dependent instability/flexibility: a comparative analysis of the structure and dynamics of wild-type transthyretin and its pathogenic variants.
    Lei M; Yang M; Huo S
    J Struct Biol; 2004 Nov; 148(2):153-68. PubMed ID: 15477096
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structures of human transthyretin complexed with glabridin.
    Yokoyama T; Kosaka Y; Mizuguchi M
    J Med Chem; 2014 Feb; 57(3):1090-6. PubMed ID: 24422526
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural evidence for asymmetric ligand binding to transthyretin.
    Cianci M; Folli C; Zonta F; Florio P; Berni R; Zanotti G
    Acta Crystallogr D Biol Crystallogr; 2015 Aug; 71(Pt 8):1582-92. PubMed ID: 26249340
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Binding of amyloidogenic transthyretin to the plasma membrane alters membrane fluidity and induces neurotoxicity.
    Hou X; Richardson SJ; Aguilar MI; Small DH
    Biochemistry; 2005 Aug; 44(34):11618-27. PubMed ID: 16114899
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
    Zanotti G; Cendron L; Folli C; Florio P; Imbimbo BP; Berni R
    FEBS Lett; 2013 Aug; 587(15):2325-31. PubMed ID: 23792159
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chromium(III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation.
    Sato T; Ando Y; Susuki S; Mikami F; Ikemizu S; Nakamura M; Suhr O; Anraku M; Kai T; Suico MA; Shuto T; Mizuguchi M; Yamagata Y; Kai H
    FEBS Lett; 2006 Jan; 580(2):491-6. PubMed ID: 16386248
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dissecting the structure, thermodynamic stability, and aggregation properties of the A25T transthyretin (A25T-TTR) variant involved in leptomeningeal amyloidosis: identifying protein partners that co-aggregate during A25T-TTR fibrillogenesis in cerebrospinal fluid.
    Azevedo EP; Pereira HM; Garratt RC; Kelly JW; Foguel D; Palhano FL
    Biochemistry; 2011 Dec; 50(51):11070-83. PubMed ID: 22091638
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enthalpic Forces Correlate with the Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma.
    Iakovleva I; Brännström K; Nilsson L; Gharibyan AL; Begum A; Anan I; Walfridsson M; Sauer-Eriksson AE; Olofsson A
    J Med Chem; 2015 Aug; 58(16):6507-15. PubMed ID: 26214366
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Retention of misfolded mutant transthyretin by the chaperone BiP/GRP78 mitigates amyloidogenesis.
    Sörgjerd K; Ghafouri B; Jonsson BH; Kelly JW; Blond SY; Hammarström P
    J Mol Biol; 2006 Feb; 356(2):469-82. PubMed ID: 16376939
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transthyretin stability as a key factor in amyloidogenesis: X-ray analysis at atomic resolution.
    Sebastião MP; Lamzin V; Saraiva MJ; Damas AM
    J Mol Biol; 2001 Mar; 306(4):733-44. PubMed ID: 11243784
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural insights into a zinc-dependent pathway leading to Leu55Pro transthyretin amyloid fibrils.
    Castro-Rodrigues AF; Gales L; Saraiva MJ; Damas AM
    Acta Crystallogr D Biol Crystallogr; 2011 Dec; 67(Pt 12):1035-44. PubMed ID: 22120741
    [TBL] [Abstract][Full Text] [Related]  

  • 19. X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis.
    Neto-Silva RM; Macedo-Ribeiro S; Pereira PJ; Coll M; Saraiva MJ; Damas AM
    Acta Crystallogr D Biol Crystallogr; 2005 Mar; 61(Pt 3):333-9. PubMed ID: 15735344
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation.
    Ferreira N; Saraiva MJ; Almeida MR
    FEBS Lett; 2011 Aug; 585(15):2424-30. PubMed ID: 21740906
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.