BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 22842534)

  • 1. Presenilins: role in calcium homeostasis.
    Honarnejad K; Herms J
    Int J Biochem Cell Biol; 2012 Nov; 44(11):1983-6. PubMed ID: 22842534
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Presenilins as endoplasmic reticulum calcium leak channels and Alzheimer's disease pathogenesis.
    Supnet C; Bezprozvanny I
    Sci China Life Sci; 2011 Aug; 54(8):744-51. PubMed ID: 21786197
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Presenilins as Drug Targets for Alzheimer's Disease-Recent Insights from Cell Biology and Electrophysiology as Novel Opportunities in Drug Development.
    Duncan RS; Song B; Koulen P
    Int J Mol Sci; 2018 May; 19(6):. PubMed ID: 29857474
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Presenilins: how much more than γ-secretase?!
    Coen K; Annaert W
    Biochem Soc Trans; 2010 Dec; 38(6):1474-8. PubMed ID: 21118110
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Physiological functions of presenilins; beyond γ-secretase.
    Stiller I; Lizák B; Bánhegyi G
    Curr Pharm Biotechnol; 2014; 15(11):1019-25. PubMed ID: 25420727
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Beyond γ-secretase activity: The multifunctional nature of presenilins in cell signalling pathways.
    Duggan SP; McCarthy JV
    Cell Signal; 2016 Jan; 28(1):1-11. PubMed ID: 26498858
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Presenilins are novel substrates for TRAF6-mediated ubiquitination.
    Yan R; Farrelly S; McCarthy JV
    Cell Signal; 2013 Sep; 25(9):1769-79. PubMed ID: 23707529
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Presenilins and calcium signaling-systems biology to the rescue.
    Bezprozvanny I
    Sci Signal; 2013 Jul; 6(283):pe24. PubMed ID: 23838181
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
    Sevalle J; Ayral E; Hernandez JF; Martinez J; Checler F
    J Neurochem; 2009 Jul; 110(1):275-83. PubMed ID: 19457123
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Presenilin diversifies its portfolio.
    Parks AL; Curtis D
    Trends Genet; 2007 Mar; 23(3):140-50. PubMed ID: 17280736
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel research horizons for presenilins and γ-secretases in cell biology and disease.
    De Strooper B; Annaert W
    Annu Rev Cell Dev Biol; 2010; 26():235-60. PubMed ID: 20604710
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Presenilin-mediated signal transduction.
    Cowburn RF; Popescu BO; Ankarcrona M; Dehvari N; Cedazo-Minguez A
    Physiol Behav; 2007 Sep; 92(1-2):93-7. PubMed ID: 17568632
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Familial Alzheimer's disease mutations in presenilins: effects on endoplasmic reticulum calcium homeostasis and correlation with clinical phenotypes.
    Nelson O; Supnet C; Liu H; Bezprozvanny I
    J Alzheimers Dis; 2010; 21(3):781-93. PubMed ID: 20634584
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neuronal calcium signaling and Alzheimer's disease.
    Woods NK; Padmanabhan J
    Adv Exp Med Biol; 2012; 740():1193-217. PubMed ID: 22453989
    [TBL] [Abstract][Full Text] [Related]  

  • 15. γ-Secretase component presenilin is important for microglia β-amyloid clearance.
    Farfara D; Trudler D; Segev-Amzaleg N; Galron R; Stein R; Frenkel D
    Ann Neurol; 2011 Jan; 69(1):170-80. PubMed ID: 21280087
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Molecular basics of Alzheimer's disease].
    Grigorenko AP; Rogaev EI
    Mol Biol (Mosk); 2007; 41(2):331-45. PubMed ID: 17514900
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alzheimer's disease sends the wrong signals--a perspective.
    Neve RL
    Amyloid; 2008 Mar; 15(1):1-4. PubMed ID: 18266116
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations.
    Tu H; Nelson O; Bezprozvanny A; Wang Z; Lee SF; Hao YH; Serneels L; De Strooper B; Yu G; Bezprozvanny I
    Cell; 2006 Sep; 126(5):981-93. PubMed ID: 16959576
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease.
    Wolfe MS; De Los Angeles J; Miller DD; Xia W; Selkoe DJ
    Biochemistry; 1999 Aug; 38(35):11223-30. PubMed ID: 10471271
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.
    Wolfe MS; Xia W; Ostaszewski BL; Diehl TS; Kimberly WT; Selkoe DJ
    Nature; 1999 Apr; 398(6727):513-7. PubMed ID: 10206644
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.