These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 22846992)

  • 21. Negative allosteric modulators of cannabinoid receptor 1: Ternary complexes including CB1, orthosteric CP55940 and allosteric ORG27569.
    Aderibigbe AO; Pandey P; Doerksen RJ
    J Biomol Struct Dyn; 2022 Aug; 40(13):5729-5747. PubMed ID: 33480332
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Rational design of cannabinoid type-1 receptor allosteric modulators: Org27569 and PSNCBAM-1 hybrids.
    Nguyen T; Gamage TF; Decker AM; Finlay DB; Langston TL; Barrus D; Glass M; Harris DL; Zhang Y
    Bioorg Med Chem; 2021 Jul; 41():116215. PubMed ID: 34015703
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Enantiomer-specific positive allosteric modulation of CB
    Mitjavila J; Yin D; Kulkarni PM; Zanato C; Thakur GA; Ross R; Greig I; Mackie K; Straiker A
    Pharmacol Res; 2018 Mar; 129():475-481. PubMed ID: 29158048
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence.
    Slivicki RA; Xu Z; Kulkarni PM; Pertwee RG; Mackie K; Thakur GA; Hohmann AG
    Biol Psychiatry; 2018 Nov; 84(10):722-733. PubMed ID: 28823711
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: evidence from postmortem human brain.
    Erdozain AM; Diez-Alarcia R; Meana JJ; Callado LF
    Biochem Pharmacol; 2012 Jan; 83(2):260-8. PubMed ID: 22093909
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor.
    Laprairie RB; Kulkarni PM; Deschamps JR; Kelly MEM; Janero DR; Cascio MG; Stevenson LA; Pertwee RG; Kenakin TP; Denovan-Wright EM; Thakur GA
    ACS Chem Neurosci; 2017 Jun; 8(6):1188-1203. PubMed ID: 28103441
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Purification of Functional CB
    Fay JF; Farrens DL
    Methods Enzymol; 2017; 593():343-370. PubMed ID: 28750810
    [TBL] [Abstract][Full Text] [Related]  

  • 28. F200A substitution in the third transmembrane helix of human cannabinoid CB1 receptor converts AM2233 from receptor agonist to inverse agonist.
    Shen CP; Xiao JC; Armstrong H; Hagmann W; Fong TM
    Eur J Pharmacol; 2006 Feb; 531(1-3):41-6. PubMed ID: 16438957
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Multiple Binding Sites Contribute to the Mechanism of Mixed Agonistic and Positive Allosteric Modulators of the Cannabinoid CB1 Receptor.
    Saleh N; Hucke O; Kramer G; Schmidt E; Montel F; Lipinski R; Ferger B; Clark T; Hildebrand PW; Tautermann CS
    Angew Chem Int Ed Engl; 2018 Mar; 57(10):2580-2585. PubMed ID: 29314474
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Biased Agonism and Biased Allosteric Modulation at the CB1 Cannabinoid Receptor.
    Khajehali E; Malone DT; Glass M; Sexton PM; Christopoulos A; Leach K
    Mol Pharmacol; 2015 Aug; 88(2):368-79. PubMed ID: 26044547
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Allosteric Modulation of the CB1 Cannabinoid Receptor by Cannabidiol-A Molecular Modeling Study of the N-Terminal Domain and the Allosteric-Orthosteric Coupling.
    Jakowiecki J; Abel R; Orzeł U; Pasznik P; Preissner R; Filipek S
    Molecules; 2021 Apr; 26(9):. PubMed ID: 33922473
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Modeling of ligand binding to G protein coupled receptors: cannabinoid CB1, CB2 and adrenergic β 2 AR.
    Latek D; Kolinski M; Ghoshdastider U; Debinski A; Bombolewski R; Plazinska A; Jozwiak K; Filipek S
    J Mol Model; 2011 Sep; 17(9):2353-66. PubMed ID: 21365223
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Allosteric Cannabinoid Receptor 1 (CB1) Ligands Reduce Ocular Pain and Inflammation.
    Thapa D; Cairns EA; Szczesniak AM; Kulkarni PM; Straiker AJ; Thakur GA; Kelly MEM
    Molecules; 2020 Jan; 25(2):. PubMed ID: 31968549
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Pharmacophores for ligand recognition and activation/inactivation of the cannabinoid receptors.
    Reggio PH
    Curr Pharm Des; 2003; 9(20):1607-33. PubMed ID: 12871061
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Ligand-specific homology modeling of human cannabinoid (CB1) receptor.
    Ai R; Chang CE
    J Mol Graph Model; 2012 Sep; 38():155-64. PubMed ID: 23079645
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Structure-activity relationships of substituted 1H-indole-2-carboxamides as CB1 receptor allosteric modulators.
    Nguyen T; German N; Decker AM; Li JX; Wiley JL; Thomas BF; Kenakin TP; Zhang Y
    Bioorg Med Chem; 2015 May; 23(9):2195-2203. PubMed ID: 25797163
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Interactions between CB1 cannabinoid and mu opioid receptors mediating inhibition of neurotransmitter release in rat nucleus accumbens core.
    Schoffelmeer AN; Hogenboom F; Wardeh G; De Vries TJ
    Neuropharmacology; 2006 Sep; 51(4):773-81. PubMed ID: 16806307
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Membrane Lipids Are an Integral Part of Transmembrane Allosteric Sites in GPCRs: A Case Study of Cannabinoid CB1 Receptor Bound to a Negative Allosteric Modulator, ORG27569, and Analogs.
    Obi P; Natesan S
    J Med Chem; 2022 Sep; 65(18):12240-12255. PubMed ID: 36066412
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Evaluation of the in vivo receptor occupancy for the behavioral effects of cannabinoids using a radiolabeled cannabinoid receptor agonist, R-[125/131I]AM2233.
    Dhawan J; Deng H; Gatley SJ; Makriyannis A; Akinfeleye T; Bruneus M; Dimaio AA; Gifford AN
    Synapse; 2006 Aug; 60(2):93-101. PubMed ID: 16715483
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Aiming for allosterism: Evaluation of allosteric modulators of CB1 in a neuronal model.
    Straiker A; Mitjavila J; Yin D; Gibson A; Mackie K
    Pharmacol Res; 2015 Sep; 99():370-6. PubMed ID: 26211948
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.