These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 22851002)

  • 1. The role of G-domain orientation and nucleotide state on the Ras isoform-specific membrane interaction.
    Kapoor S; Weise K; Erlkamp M; Triola G; Waldmann H; Winter R
    Eur Biophys J; 2012 Oct; 41(10):801-13. PubMed ID: 22851002
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The higher level of complexity of K-Ras4B activation at the membrane.
    Jang H; Banerjee A; Chavan TS; Lu S; Zhang J; Gaponenko V; Nussinov R
    FASEB J; 2016 Apr; 30(4):1643-55. PubMed ID: 26718888
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Membrane-mediated induction and sorting of K-Ras microdomain signaling platforms.
    Weise K; Kapoor S; Denter C; Nikolaus J; Opitz N; Koch S; Triola G; Herrmann A; Waldmann H; Winter R
    J Am Chem Soc; 2011 Feb; 133(4):880-7. PubMed ID: 21141956
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site.
    Lu S; Banerjee A; Jang H; Zhang J; Gaponenko V; Nussinov R
    J Biol Chem; 2015 Nov; 290(48):28887-900. PubMed ID: 26453300
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of membrane binding of small GTPase K-Ras4B farnesylated hypervariable region.
    Jang H; Abraham SJ; Chavan TS; Hitchinson B; Khavrutskii L; Tarasova NI; Nussinov R; Gaponenko V
    J Biol Chem; 2015 Apr; 290(15):9465-77. PubMed ID: 25713064
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site.
    Chavan TS; Jang H; Khavrutskii L; Abraham SJ; Banerjee A; Freed BC; Johannessen L; Tarasov SG; Gaponenko V; Nussinov R; Tarasova NI
    Biophys J; 2015 Dec; 109(12):2602-2613. PubMed ID: 26682817
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel switch region regulates H-ras membrane orientation and signal output.
    Abankwa D; Hanzal-Bayer M; Ariotti N; Plowman SJ; Gorfe AA; Parton RG; McCammon JA; Hancock JF
    EMBO J; 2008 Mar; 27(5):727-35. PubMed ID: 18273062
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Markov State Models and Molecular Dynamics Simulations Reveal the Conformational Transition of the Intrinsically Disordered Hypervariable Region of K-Ras4B to the Ordered Conformation.
    Zhang H; Ni D; Fan J; Li M; Zhang J; Hua C; Nussinov R; Lu S
    J Chem Inf Model; 2022 Sep; 62(17):4222-4231. PubMed ID: 35994329
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane.
    Rotblat B; Prior IA; Muncke C; Parton RG; Kloog Y; Henis YI; Hancock JF
    Mol Cell Biol; 2004 Aug; 24(15):6799-810. PubMed ID: 15254246
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interaction of the human N-Ras protein with lipid raft model membranes of varying degrees of complexity.
    Vogel A; Nikolaus J; Weise K; Triola G; Waldmann H; Winter R; Herrmann A; Huster D
    Biol Chem; 2014 Jul; 395(7-8):779-89. PubMed ID: 24526608
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Conserved allosteric perturbation of the GTPase domains by region 1 of Ras hypervariable regions.
    Gu X; Zhang Y; Long D
    Biophys J; 2024 Apr; 123(7):839-846. PubMed ID: 38419331
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Study of Förster Resonance Energy Transfer to Lipid Domain Markers Ascertains Partitioning of Semisynthetic Lipidated N-Ras in Lipid Raft Nanodomains.
    Shishina AK; Kovrigina EA; Galiakhmetov AR; Rathore R; Kovrigin EL
    Biochemistry; 2018 Feb; 57(5):872-881. PubMed ID: 29280621
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mapping the nucleotide and isoform-dependent structural and dynamical features of Ras proteins.
    Gorfe AA; Grant BJ; McCammon JA
    Structure; 2008 Jun; 16(6):885-96. PubMed ID: 18547521
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Visualizing association of lipidated signaling proteins in heterogeneous membranes--partitioning into subdomains, lipid sorting, interfacial adsorption, and protein association.
    Weise K; Triola G; Janosch S; Waldmann H; Winter R
    Biochim Biophys Acta; 2010 Jul; 1798(7):1409-17. PubMed ID: 20025847
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Secondary structure of lipidated Ras bound to a lipid bilayer.
    Güldenhaupt J; Adigüzel Y; Kuhlmann J; Waldmann H; Kötting C; Gerwert K
    FEBS J; 2008 Dec; 275(23):5910-8. PubMed ID: 19021766
    [TBL] [Abstract][Full Text] [Related]  

  • 16. GTP-dependent segregation of H-ras from lipid rafts is required for biological activity.
    Prior IA; Harding A; Yan J; Sluimer J; Parton RG; Hancock JF
    Nat Cell Biol; 2001 Apr; 3(4):368-75. PubMed ID: 11283610
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ras membrane orientation and nanodomain localization generate isoform diversity.
    Abankwa D; Gorfe AA; Inder K; Hancock JF
    Proc Natl Acad Sci U S A; 2010 Jan; 107(3):1130-5. PubMed ID: 20080631
    [TBL] [Abstract][Full Text] [Related]  

  • 18. K-Ras G-domain binding with signaling lipid phosphatidylinositol (4,5)-phosphate (PIP2): membrane association, protein orientation, and function.
    Cao S; Chung S; Kim S; Li Z; Manor D; Buck M
    J Biol Chem; 2019 Apr; 294(17):7068-7084. PubMed ID: 30792310
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing the Conformational and Energy Landscapes of KRAS Membrane Orientation.
    Prakash P; Gorfe AA
    J Phys Chem B; 2019 Oct; 123(41):8644-8652. PubMed ID: 31554397
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Time-resolved FTIR studies of the GTPase reaction of H-ras p21 reveal a key role for the beta-phosphate.
    Cepus V; Scheidig AJ; Goody RS; Gerwert K
    Biochemistry; 1998 Jul; 37(28):10263-71. PubMed ID: 9665734
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.