These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 22851929)

  • 1. Functional expression in Escherichia coli of the disulfide-rich sea anemone peptide APETx2, a potent blocker of acid-sensing ion channel 3.
    Anangi R; Rash LD; Mobli M; King GF
    Mar Drugs; 2012 Jul; 10(7):1605-1618. PubMed ID: 22851929
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3.
    Jensen JE; Mobli M; Brust A; Alewood PF; King GF; Rash LD
    Mar Drugs; 2012 Jul; 10(7):1511-1527. PubMed ID: 22851922
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons.
    Diochot S; Baron A; Rash LD; Deval E; Escoubas P; Scarzello S; Salinas M; Lazdunski M
    EMBO J; 2004 Apr; 23(7):1516-25. PubMed ID: 15044953
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In silico assessment of interaction of sea anemone toxin APETx2 and acid sensing ion channel 3.
    Rahman T; Smith ES
    Biochem Biophys Res Commun; 2014 Jul; 450(1):384-9. PubMed ID: 24942880
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression in Pichia pastoris and characterization of APETx2, a specific inhibitor of acid sensing ion channel 3.
    Anangi R; Chen CC; Lin YW; Cheng YR; Cheng CH; Chen YC; Chu YP; Chuang WJ
    Toxicon; 2010 Dec; 56(8):1388-97. PubMed ID: 20813121
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain.
    Lee JYP; Saez NJ; Cristofori-Armstrong B; Anangi R; King GF; Smith MT; Rash LD
    Br J Pharmacol; 2018 Jun; 175(12):2204-2218. PubMed ID: 29134638
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of voltage-gated Na(+) currents in sensory neurones by the sea anemone toxin APETx2.
    Blanchard MG; Rash LD; Kellenberger S
    Br J Pharmacol; 2012 Apr; 165(7):2167-77. PubMed ID: 21943094
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Understanding the molecular basis of toxin promiscuity: the analgesic sea anemone peptide APETx2 interacts with acid-sensing ion channel 3 and hERG channels via overlapping pharmacophores.
    Jensen JE; Cristofori-Armstrong B; Anangi R; Rosengren KJ; Lau CH; Mobli M; Brust A; Alewood PF; King GF; Rash LD
    J Med Chem; 2014 Nov; 57(21):9195-203. PubMed ID: 25337890
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels.
    Chagot B; Escoubas P; Diochot S; Bernard C; Lazdunski M; Darbon H
    Protein Sci; 2005 Aug; 14(8):2003-10. PubMed ID: 15987885
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3.
    Jensen JE; Durek T; Alewood PF; Adams DJ; King GF; Rash LD
    Toxicon; 2009 Jul; 54(1):56-61. PubMed ID: 19306891
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of an Acid-sensing Ion Channels Inhibitor on Pain-related Behavior by Nucleus Pulposus Applied on the Nerve Root in Rats.
    Kobayashi Y; Sekiguchi M; Konno SI
    Spine (Phila Pa 1976); 2017 Jun; 42(11):E633-E641. PubMed ID: 27879566
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Analgesic Activity of Acid-Sensing Ion Channel 3 (ASIС3) Inhibitors: Sea Anemones Peptides Ugr9-1 and APETx2 versus Low Molecular Weight Compounds.
    Andreev YA; Osmakov DI; Koshelev SG; Maleeva EE; Logashina YA; Palikov VA; Palikova YA; Dyachenko IA; Kozlov SA
    Mar Drugs; 2018 Dec; 16(12):. PubMed ID: 30545037
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reversal of acid-induced and inflammatory pain by the selective ASIC3 inhibitor, APETx2.
    Karczewski J; Spencer RH; Garsky VM; Liang A; Leitl MD; Cato MJ; Cook SP; Kane S; Urban MO
    Br J Pharmacol; 2010 Oct; 161(4):950-60. PubMed ID: 20860671
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Peptides inhibitors of acid-sensing ion channels.
    Diochot S; Salinas M; Baron A; Escoubas P; Lazdunski M
    Toxicon; 2007 Feb; 49(2):271-84. PubMed ID: 17113616
    [TBL] [Abstract][Full Text] [Related]  

  • 15. APETx-Like Peptides from the Sea Anemone
    Kalina RS; Koshelev SG; Zelepuga EA; Kim NY; Kozlov SA; Kozlovskaya EP; Monastyrnaya MM; Gladkikh IN
    Toxins (Basel); 2020 Apr; 12(4):. PubMed ID: 32326130
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ASIC2a overexpression enhances the protective effect of PcTx1 and APETx2 against acidosis-induced articular chondrocyte apoptosis and cytotoxicity.
    Zhou RP; Ni WL; Dai BB; Wu XS; Wang ZS; Xie YY; Wang ZQ; Yang WJ; Ge JF; Hu W; Chen FH
    Gene; 2018 Feb; 642():230-240. PubMed ID: 29141196
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acid-sensing ion channels detect moderate acidifications to induce ocular pain.
    Callejo G; Castellanos A; Castany M; Gual A; Luna C; Acosta MC; Gallar J; Giblin JP; Gasull X
    Pain; 2015 Mar; 156(3):483-495. PubMed ID: 25687542
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Local ASIC3 modulates pain and disease progression in a rat model of osteoarthritis.
    Izumi M; Ikeuchi M; Ji Q; Tani T
    J Biomed Sci; 2012 Aug; 19(1):77. PubMed ID: 22909215
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Elevated Expression of Acid-Sensing Ion Channel 3 Inhibits Epilepsy via Activation of Interneurons.
    Cao Q; Wang W; Gu J; Jiang G; Wang K; Xu Z; Li J; Chen G; Wang X
    Mol Neurobiol; 2016 Jan; 53(1):485-498. PubMed ID: 25476599
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Preventing the induction of acid saline-induced fibromyalgia pain in mice by electroacupuncture or APETx2 injection.
    Yen LT; Hsieh CL; Hsu HC; Lin YW
    Acupunct Med; 2020 Jun; 38(3):188-193. PubMed ID: 31986902
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.