140 related articles for article (PubMed ID: 2285975)
1. Novel 1,4-dihydropyridine calcium antagonists. I. Synthesis and hypotensive activity of 4-(substituted pyridyl)-1,4-dihydropyridine derivatives.
Ashimori A; Ono T; Uchida T; Ohtaki Y; Fukaya C; Watanabe M; Yokoyama K
Chem Pharm Bull (Tokyo); 1990 Sep; 38(9):2446-58. PubMed ID: 2285975
[TBL] [Abstract][Full Text] [Related]
2. Novel 1,4-dihydropyridine calcium antagonists. II. Synthesis and antihypertensive activity of 3-[4-(substituted amino)phenylalkyl]ester derivatives.
Ashimori A; Ono T; Inoue Y; Morimoto S; Eda M; Uchida T; Ohtaki Y; Fujino Y; Kido H; Ogura Y
Chem Pharm Bull (Tokyo); 1991 Jan; 39(1):91-9. PubMed ID: 2049813
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and calcium channel-modulating effects of alkyl (or cycloalkyl) 1,4-dihydro-2,6-dimethyl-3-nitro-4-pyridyl-5-pyridinecarboxylate racemates and enantiomers.
Ramesh M; Matowe WC; Akula MR; Vo D; Dagnino L; Li-Kwong-Ken MC; Wolowyk MW; Knaus EE
J Med Chem; 1998 Feb; 41(4):509-14. PubMed ID: 9484501
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and antihypertensive activity of 1,4-dihydropyridine derivatives with a 4-(disubstituted phenyl) ring and an aminoalkyl ester group: highly potent and long-lasting calcium antagonists.
Kanno H; Yamaguchi H; Okamiya Y; Sunakawa K; Takeshita T; Naruchi T
Chem Pharm Bull (Tokyo); 1992 Aug; 40(8):2049-54. PubMed ID: 1423758
[TBL] [Abstract][Full Text] [Related]
5. Novel 2-amino-1,4-dihydropyridine calcium antagonists. II. Synthesis and antihypertensive effects of 2-amino-1,4-dihydropyridine derivatives having N,N-dialkylaminoalkoxycarbonyl groups at 3- and/or 5-position.
Kobayashi T; Inoue T; Nishino S; Fujihara Y; Oizumi K; Kimura T
Chem Pharm Bull (Tokyo); 1995 May; 43(5):797-817. PubMed ID: 7553967
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and calcium channel antagonist activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-[3-(1-methoxy-carbonyl-4-substituted-1,4- dihydro-pyridyl)]-3,5-pyridinedicarboxylates.
Ramesh M; Matowe WC; Knaus EE; Wolowyk MW
Drug Des Discov; 1992 Jul; 8(4):313-23. PubMed ID: 1445996
[TBL] [Abstract][Full Text] [Related]
7. Novel 2-amino-1,4-dihydropyridine calcium antagonists. I. Synthesis and antihypertensive effects of 2-amino-1,4-dihydropyridine derivatives having nitroxy-alkoxycarbonyl groups at 3- and/or 5-position.
Kobayashi T; Inoue T; Kita Z; Yoshiya H; Nishino S; Oizumi K; Kimura T
Chem Pharm Bull (Tokyo); 1995 May; 43(5):788-96. PubMed ID: 7553966
[TBL] [Abstract][Full Text] [Related]
8. Permanently charged chiral 1,4-dihydropyridines: molecular probes of L-type calcium channels. Synthesis and pharmacological characterization of methyl(omega-trimethylalkylammonium) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate iodide, calcium channel antagonists.
Peri R; Padmanabhan S; Rutledge A; Singh S; Triggle DJ
J Med Chem; 2000 Jul; 43(15):2906-14. PubMed ID: 10956198
[TBL] [Abstract][Full Text] [Related]
9. The new generation dihydropyridine type calcium blockers, bearing 4-phenyl oxypropanolamine, display alpha-/beta-adrenoceptor antagonist and long-acting antihypertensive activities.
Liang JC; Yeh JL; Wang CS; Liou SF; Tsai CH; Chen IJ
Bioorg Med Chem; 2002 Mar; 10(3):719-30. PubMed ID: 11814861
[TBL] [Abstract][Full Text] [Related]
10. Comparative QSAR studies of two series of 1,4-dihydropyridines as slow calcium channel blockers.
Wikel JH; Bemis KG; Kurz K; Denney ML; Main BW; Moore RA; Smith T; Shingleton L; Holland DR
Drug Des Discov; 1994 Jan; 11(1):1-14. PubMed ID: 8068815
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and calcium channel antagonist activity of 1,4-dihydropyridine derivatives containing 4-nitroimidazolyl substituents.
Shafiee A; Rastkary N; Jorjani M
Arzneimittelforschung; 2002; 52(7):537-42. PubMed ID: 12189777
[TBL] [Abstract][Full Text] [Related]
12. 1,4-Dihydropyridine derivatives as calcium channel modulators: the role of 3-methoxy-flavone moiety.
Budriesi R; Bisi A; Ioan P; Rampa A; Gobbi S; Belluti F; Piazzi L; Valenti P; Chiarini A
Bioorg Med Chem; 2005 May; 13(10):3423-30. PubMed ID: 15848754
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and calcium channel antagonist activity of 3-arylmethyl 5-isopropyl 1,4-dihydro-2,6-dimethyl-4-(pyridyl)-3,5-pyridinedicarboxylates.
Akula MR; Matowe WC; Wolowyk MW; Knaus EE
Pharm Res; 1990 Sep; 7(9):919-22. PubMed ID: 2235890
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of 1,4-dihydropyridine calcium channel modulators having a diazen-1-ium-1,2-diolate nitric oxide donor moiety for the potential treatment of congestive heart failure.
Velázquez C; Knaus EE
Bioorg Med Chem; 2004 Jul; 12(14):3831-40. PubMed ID: 15210150
[TBL] [Abstract][Full Text] [Related]
15. Calcium channel blocking and positive inotropic activities of ethyl 5-cyano-1,4-dihydro-6-methyl-2-[(phenylsulfonyl)methyl]-4-aryl-3- pyridine-carboxylate and analogues. Synthesis and structure-activity relationships.
Sircar I; Gregor EK; Anderson KR; Haleen SJ; Shih YH; Weishaar RE; Steffen RP; Pugsley TA; Taylor MD
J Med Chem; 1991 Jul; 34(7):2248-60. PubMed ID: 2066997
[TBL] [Abstract][Full Text] [Related]
16. Long-acting dihydropyridine calcium antagonists. 3. Synthesis and structure-activity relationships for a series of 2-[(heterocyclylmethoxy)methyl] derivatives.
Alker D; Campbell SF; Cross PE; Burges RA; Carter AJ; Gardiner DG
J Med Chem; 1989 Oct; 32(10):2381-8. PubMed ID: 2795609
[TBL] [Abstract][Full Text] [Related]
17. Effects of the novel water-soluble calcium antagonist (+/-)-3-(4-allyl-1-piperazinyl)-2,2-dimethylpropyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate dihydrochloride on the responses of isolated canine arteries.
Kanda M; Shirahase H; Kurahashi K; Wada K; Nakamura S; Matsui H; Fukata F
Arzneimittelforschung; 1995 Aug; 45(8):831-5. PubMed ID: 7575741
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and antihypertensive activities of new 1,4-dihydropyridine containing nitroimidazolyl substituent with a nitrooxy group at the 3-ester position.
Shafiee A; Rastkary N; Jorjani M; Shafaghi B
Arch Pharm (Weinheim); 2002 Mar; 335(2-3):69-76. PubMed ID: 12043457
[TBL] [Abstract][Full Text] [Related]
19. Long-acting dihydropyridine calcium antagonists. 5. Synthesis and structure-activity relationships for a series of 2-[[(N-substituted-heterocyclyl)ethoxy]methyl]-1,4-dihydropyridine calcium antagonists.
Alker D; Campbell SF; Cross PE; Burges RA; Carter AJ; Gardiner DG
J Med Chem; 1990 Jun; 33(6):1805-11. PubMed ID: 2342074
[TBL] [Abstract][Full Text] [Related]
20. Synthesis of 1,4-dihydropyridine-5-phosphonates and their calcium-antagonistic and antihypertensive activities: novel calcium-antagonist 2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dim ethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate hydrochloride ethanol (NZ-105) and its crystal structure.
Sakoda R; Kamikawaji Y; Seto K
Chem Pharm Bull (Tokyo); 1992 Sep; 40(9):2362-9. PubMed ID: 1446356
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
