BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

378 related articles for article (PubMed ID: 22861499)

  • 1. Novel second-generation di-2-pyridylketone thiosemicarbazones show synergism with standard chemotherapeutics and demonstrate potent activity against lung cancer xenografts after oral and intravenous administration in vivo.
    Lovejoy DB; Sharp DM; Seebacher N; Obeidy P; Prichard T; Stefani C; Basha MT; Sharpe PC; Jansson PJ; Kalinowski DS; Bernhardt PV; Richardson DR
    J Med Chem; 2012 Aug; 55(16):7230-44. PubMed ID: 22861499
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel thiosemicarbazones of the ApT and DpT series and their copper complexes: identification of pronounced redox activity and characterization of their antitumor activity.
    Jansson PJ; Sharpe PC; Bernhardt PV; Richardson DR
    J Med Chem; 2010 Aug; 53(15):5759-69. PubMed ID: 20597487
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.
    Kalinowski DS; Yu Y; Sharpe PC; Islam M; Liao YT; Lovejoy DB; Kumar N; Bernhardt PV; Richardson DR
    J Med Chem; 2007 Jul; 50(15):3716-29. PubMed ID: 17602603
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alkyl substituted 2'-benzoylpyridine thiosemicarbazone chelators with potent and selective anti-neoplastic activity: novel ligands that limit methemoglobin formation.
    Stefani C; Jansson PJ; Gutierrez E; Bernhardt PV; Richardson DR; Kalinowski DS
    J Med Chem; 2013 Jan; 56(1):357-70. PubMed ID: 23276209
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2-Acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: redox activity, iron complexation and characterization of their antitumor activity.
    Richardson DR; Kalinowski DS; Richardson V; Sharpe PC; Lovejoy DB; Islam M; Bernhardt PV
    J Med Chem; 2009 Mar; 52(5):1459-70. PubMed ID: 19216562
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Halogenated 2'-benzoylpyridine thiosemicarbazone (XBpT) chelators with potent and selective anti-neoplastic activity: relationship to intracellular redox activity.
    Stefani C; Punnia-Moorthy G; Lovejoy DB; Jansson PJ; Kalinowski DS; Sharpe PC; Bernhardt PV; Richardson DR
    J Med Chem; 2011 Oct; 54(19):6936-48. PubMed ID: 21846118
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, Characterization, and in Vitro Anticancer Activity of Copper and Zinc Bis(Thiosemicarbazone) Complexes.
    Anjum R; Palanimuthu D; Kalinowski DS; Lewis W; Park KC; Kovacevic Z; Khan IU; Richardson DR
    Inorg Chem; 2019 Oct; 58(20):13709-13723. PubMed ID: 31339305
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Methemoglobin formation by triapine, di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone (Dp44mT), and other anticancer thiosemicarbazones: identification of novel thiosemicarbazones and therapeutics that prevent this effect.
    Quach P; Gutierrez E; Basha MT; Kalinowski DS; Sharpe PC; Lovejoy DB; Bernhardt PV; Jansson PJ; Richardson DR
    Mol Pharmacol; 2012 Jul; 82(1):105-14. PubMed ID: 22508546
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nitroimidazole and glucosamine conjugated heteroscorpionate ligands and related copper(II) complexes. Syntheses, biological activity and XAS studies.
    Pellei M; Papini G; Trasatti A; Giorgetti M; Tonelli D; Minicucci M; Marzano C; Gandin V; Aquilanti G; Dolmella A; Santini C
    Dalton Trans; 2011 Oct; 40(38):9877-88. PubMed ID: 21709917
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells.
    Ohui K; Stepanenko I; Besleaga I; Babak MV; Stafi R; Darvasiova D; Giester G; Pósa V; Enyedy EA; Vegh D; Rapta P; Ang WH; Popović-Bijelić A; Arion VB
    Biomolecules; 2020 Sep; 10(9):. PubMed ID: 32961653
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, crystal structures and spectroscopy of meclofenamic acid and its metal complexes with manganese(II), copper(II), zinc(II) and cadmium(II). Antiproliferative and superoxide dismutase activity.
    Kovala-Demertzi D; Staninska M; Garcia-Santos I; Castineiras A; Demertzis MA
    J Inorg Biochem; 2011 Sep; 105(9):1187-95. PubMed ID: 21718655
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, characterization and antitumor activity of polymeric copper(II) complexes with thiosemicarbazones of 3-methyl-5-oxo-1-phenyl-3-pyrazolin-4-carboxaldehyde and 5-oxo-3-phenyl-3-pyrazolin-4-carboxaldehyde.
    Leovac VM; Bogdanović GA; Jovanović LS; Joksović L; Marković V; Joksović MD; Denčić SM; Isaković A; Marković I; Heinemann FW; Trifunović S; Đalović I
    J Inorg Biochem; 2011 Nov; 105(11):1413-21. PubMed ID: 21955843
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, crystal structure and antiproliferative mechanisms of 2-acetylpyridine-thiosemicarbazones Ga(III) with a greater selectivity against tumor cells.
    Qi J; Zheng Y; Qian K; Tian L; Zhang GX; Cheng Z; Wang Y
    J Inorg Biochem; 2017 Dec; 177():110-117. PubMed ID: 28946027
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.
    Kowol CR; Trondl R; Heffeter P; Arion VB; Jakupec MA; Roller A; Galanski MS; Berger W; Keppler BK
    J Med Chem; 2009 Aug; 52(16):5032-43. PubMed ID: 19637923
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, spectral characterization and biological evaluation of Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) complexes with thiosemicarbazone ending by pyrazole and pyridyl rings.
    Yousef TA; Abu El-Reash GM; Al-Jahdali M; El-Rakhawy el-BR
    Spectrochim Acta A Mol Biomol Spectrosc; 2014 Aug; 129():163-72. PubMed ID: 24727176
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bis(thiosemicarbazones) as bifunctional chelators for the room temperature 64-copper labeling of peptides.
    Hueting R; Christlieb M; Dilworth JR; García Garayoa E; Gouverneur V; Jones MW; Maes V; Schibli R; Sun X; Tourwé DA
    Dalton Trans; 2010 Apr; 39(15):3620-32. PubMed ID: 20354615
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-activity studies of 4-phenyl-substituted 2'-benzoylpyridine thiosemicarbazones with potent and selective anti-tumour activity.
    Lukmantara AY; Kalinowski DS; Kumar N; Richardson DR
    Org Biomol Chem; 2013 Oct; 11(37):6414-25. PubMed ID: 23963445
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy.
    Yu Y; Suryo Rahmanto Y; Richardson DR
    Br J Pharmacol; 2012 Jan; 165(1):148-66. PubMed ID: 21658021
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of 2-benzoylpyridine thiosemicarbazones in a dimeric system: structure-activity relationship studies on their anti-proliferative and iron chelation efficacy.
    Lukmantara AY; Kalinowski DS; Kumar N; Richardson DR
    J Inorg Biochem; 2014 Dec; 141():43-54. PubMed ID: 25217717
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thiosemicarbazone Cu(II) and Zn(II) complexes as potential anticancer agents: syntheses, crystal structure, DNA cleavage, cytotoxicity and apoptosis induction activity.
    Shao J; Ma ZY; Li A; Liu YH; Xie CZ; Qiang ZY; Xu JY
    J Inorg Biochem; 2014 Jul; 136():13-23. PubMed ID: 24690556
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.