These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

266 related articles for article (PubMed ID: 22864238)

  • 1. Insights on cytochrome p450 enzymes and inhibitors obtained through QSAR studies.
    Sridhar J; Liu J; Foroozesh M; Stevens CL
    Molecules; 2012 Aug; 17(8):9283-305. PubMed ID: 22864238
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacophore and three-dimensional quantitative structure activity relationship methods for modeling cytochrome p450 active sites.
    Ekins S; de Groot MJ; Jones JP
    Drug Metab Dispos; 2001 Jul; 29(7):936-44. PubMed ID: 11408357
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Computational models for predicting interactions with cytochrome p450 enzyme.
    Arimoto R
    Curr Top Med Chem; 2006; 6(15):1609-18. PubMed ID: 16918472
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches.
    Stiborová M; Bárta F; Levová K; Hodek P; Schmeiser HH; Arlt VM; Martínek V
    Int J Mol Sci; 2015 Nov; 16(11):27561-75. PubMed ID: 26593908
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives.
    Shimada T; Tanaka K; Takenaka S; Murayama N; Martin MV; Foroozesh MK; Yamazaki H; Guengerich FP; Komori M
    Chem Res Toxicol; 2010 Dec; 23(12):1921-35. PubMed ID: 21053930
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In silico studies of polyaromatic hydrocarbon inhibitors of cytochrome P450 enzymes 1A1, 1A2, 2A6, and 2B1.
    Sridhar J; Jin P; Liu J; Foroozesh M; Stevens CL
    Chem Res Toxicol; 2010 Mar; 23(3):600-7. PubMed ID: 20078084
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Spectral modification and catalytic inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by four chemopreventive organoselenium compounds.
    Shimada T; Murayama N; Tanaka K; Takenaka S; Guengerich FP; Yamazaki H; Komori M
    Chem Res Toxicol; 2011 Aug; 24(8):1327-37. PubMed ID: 21732699
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Binding and Metabolism of Brominated Flame Retardant β-1,2-Dibromo-4-(1,2-dibromoethyl)cyclohexane in Human Microsomal P450 Enzymes: Insights from Computational Studies.
    Ma G; Yu H; Han C; Jia Y; Wei X; Wang Z
    Chem Res Toxicol; 2020 Jun; 33(6):1487-1496. PubMed ID: 32243142
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro metabolism and drug interaction potential of a new highly potent anti-cytomegalovirus molecule, CMV423 (2-chloro 3-pyridine 3-yl 5,6,7,8-tetrahydroindolizine I-carboxamide).
    Bournique B; Lambert N; Boukaiba R; Martinet M
    Br J Clin Pharmacol; 2001 Jul; 52(1):53-63. PubMed ID: 11453890
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.
    Zanger UM; Schwab M
    Pharmacol Ther; 2013 Apr; 138(1):103-41. PubMed ID: 23333322
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Studies of flurbiprofen 4'-hydroxylation. Additional evidence suggesting the sole involvement of cytochrome P450 2C9.
    Tracy TS; Marra C; Wrighton SA; Gonzalez FJ; Korzekwa KR
    Biochem Pharmacol; 1996 Oct; 52(8):1305-9. PubMed ID: 8937439
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nortriptyline E-10-hydroxylation in vitro is mediated by human CYP2D6 (high affinity) and CYP3A4 (low affinity): implications for interactions with enzyme-inducing drugs.
    Venkatakrishnan K; von Moltke LL; Greenblatt DJ
    J Clin Pharmacol; 1999 Jun; 39(6):567-77. PubMed ID: 10354960
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Quantitative structure-activity relationships (QSARs) for inhibitors and substrates of CYP2B enzymes: importance of compound lipophilicity in explanation of potency differences.
    Lewis DF; Ito Y; Lake BG
    J Enzyme Inhib Med Chem; 2010 Oct; 25(5):679-84. PubMed ID: 20100069
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of human cytochrome P450 3A4 in the metabolism of DA-8159, a new erectogenic.
    Ji HY; Lee HW; Kim HH; Kim DS; Yoo M; Kim WB; Lee HS
    Xenobiotica; 2004; 34(11-12):973-82. PubMed ID: 15801542
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human cytochrome P450s involved in the metabolism of 9-cis- and 13-cis-retinoic acids.
    Marill J; Capron CC; Idres N; Chabot GG
    Biochem Pharmacol; 2002 Mar; 63(5):933-43. PubMed ID: 11911845
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1.
    Jerabek P; Martinek V; Stiborova M
    Neuro Endocrinol Lett; 2012; 33 Suppl 3():25-32. PubMed ID: 23353840
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Computational Prediction of Inhibitors and Inducers of the Major Isoforms of Cytochrome P450.
    Rudik A; Dmitriev A; Lagunin A; Filimonov D; Poroikov V
    Molecules; 2022 Sep; 27(18):. PubMed ID: 36144612
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparative cytochrome P450 -1A1, -2A6, -2B6, -2C, -2D6, -2E1, -3A5 and -4B1 expressions in human larynx tissue analysed at mRNA level.
    Sarikaya D; Bilgen C; Kamataki T; Topcu Z
    Biopharm Drug Dispos; 2006 Nov; 27(8):353-9. PubMed ID: 16894644
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities.
    Doehmer J; Weiss G; McGregor GP; Appel K
    Toxicol In Vitro; 2011 Feb; 25(1):21-7. PubMed ID: 20828605
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationship for human cytochrome P450 substrates and inhibitors.
    Lewis DF; Modi S; Dickins M
    Drug Metab Rev; 2002; 34(1-2):69-82. PubMed ID: 11996013
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.