BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

337 related articles for article (PubMed ID: 22864611)

  • 1. HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity.
    Kurita M; Holloway T; García-Bea A; Kozlenkov A; Friedman AK; Moreno JL; Heshmati M; Golden SA; Kennedy PJ; Takahashi N; Dietz DM; Mocci G; Gabilondo AM; Hanks J; Umali A; Callado LF; Gallitano AL; Neve RL; Shen L; Buxbaum JD; Han MH; Nestler EJ; Meana JJ; Russo SJ; González-Maeso J
    Nat Neurosci; 2012 Sep; 15(9):1245-54. PubMed ID: 22864611
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chronic clozapine treatment restrains via HDAC2 the performance of mGlu2 receptor agonism in a rodent model of antipsychotic activity.
    de la Fuente Revenga M; Ibi D; Cuddy T; Toneatti R; Kurita M; Ijaz MK; Miles MF; Wolstenholme JT; González-Maeso J
    Neuropsychopharmacology; 2019 Jan; 44(2):443-454. PubMed ID: 30038413
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Repressive epigenetic changes at the mGlu2 promoter in frontal cortex of 5-HT2A knockout mice.
    Kurita M; Moreno JL; Holloway T; Kozlenkov A; Mocci G; García-Bea A; Hanks JB; Neve R; Nestler EJ; Russo SJ; González-Maeso J
    Mol Pharmacol; 2013 Jun; 83(6):1166-75. PubMed ID: 23508685
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of mGlu2 in the 5-HT
    Hideshima KS; Hojati A; Saunders JM; On DM; de la Fuente Revenga M; Shin JM; Sánchez-González A; Dunn CM; Pais AB; Pais AC; Miles MF; Wolstenholme JT; González-Maeso J
    Psychopharmacology (Berl); 2018 Nov; 235(11):3149-3165. PubMed ID: 30209534
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HDAC2-dependent Antipsychotic-like Effects of Chronic Treatment with the HDAC Inhibitor SAHA in Mice.
    de la Fuente Revenga M; Ibi D; Saunders JM; Cuddy T; Ijaz MK; Toneatti R; Kurita M; Holloway T; Shen L; Seto J; Dozmorov MG; González-Maeso J
    Neuroscience; 2018 Sep; 388():102-117. PubMed ID: 30025863
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Trichostatin A induces 5-lipoxygenase promoter activity and mRNA expression via inhibition of histone deacetylase 2 and 3.
    Pufahl L; Katryniok C; Schnur N; Sorg BL; Metzner J; Grez M; Steinhilber D
    J Cell Mol Med; 2012 Jul; 16(7):1461-73. PubMed ID: 21883892
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain.
    Chiechio S; Zammataro M; Morales ME; Busceti CL; Drago F; Gereau RW; Copani A; Nicoletti F
    Mol Pharmacol; 2009 May; 75(5):1014-20. PubMed ID: 19255242
    [TBL] [Abstract][Full Text] [Related]  

  • 8. L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors.
    Nasca C; Xenos D; Barone Y; Caruso A; Scaccianoce S; Matrisciano F; Battaglia G; Mathé AA; Pittaluga A; Lionetto L; Simmaco M; Nicoletti F
    Proc Natl Acad Sci U S A; 2013 Mar; 110(12):4804-9. PubMed ID: 23382250
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differences in 5-HT2A and mGlu2 Receptor Expression Levels and Repressive Epigenetic Modifications at the 5-HT2A Promoter Region in the Roman Low- (RLA-I) and High- (RHA-I) Avoidance Rat Strains.
    Fomsgaard L; Moreno JL; de la Fuente Revenga M; Brudek T; Adamsen D; Rio-Alamos C; Saunders J; Klein AB; Oliveras I; Cañete T; Blazquez G; Tobeña A; Fernandez-Teruel A; Gonzalez-Maeso J; Aznar S
    Mol Neurobiol; 2018 Mar; 55(3):1998-2012. PubMed ID: 28265857
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of intestinal serotonin transporter expression via epigenetic mechanisms: role of HDAC2.
    Gill RK; Kumar A; Malhotra P; Maher D; Singh V; Dudeja PK; Alrefai W; Saksena S
    Am J Physiol Cell Physiol; 2013 Feb; 304(4):C334-41. PubMed ID: 23195070
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 5-HT
    Murat S; Bigot M; Chapron J; König GM; Kostenis E; Battaglia G; Nicoletti F; Bourinet E; Bockaert J; Marin P; Vandermoere F
    Mol Psychiatry; 2019 Nov; 24(11):1610-1626. PubMed ID: 29858599
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests.
    Schroeder FA; Lewis MC; Fass DM; Wagner FF; Zhang YL; Hennig KM; Gale J; Zhao WN; Reis S; Barker DD; Berry-Scott E; Kim SW; Clore EL; Hooker JM; Holson EB; Haggarty SJ; Petryshen TL
    PLoS One; 2013; 8(8):e71323. PubMed ID: 23967191
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of mGlu2/3 metabotropic glutamate receptors negatively regulates the stimulation of inositol phospholipid hydrolysis mediated by 5-hydroxytryptamine2A serotonin receptors in the frontal cortex of living mice.
    Molinaro G; Traficante A; Riozzi B; Di Menna L; Curto M; Pallottino S; Nicoletti F; Bruno V; Battaglia G
    Mol Pharmacol; 2009 Aug; 76(2):379-87. PubMed ID: 19439499
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A·mGlu2) receptor heteromerization and its psychoactive behavioral function.
    Moreno JL; Muguruza C; Umali A; Mortillo S; Holloway T; Pilar-Cuéllar F; Mocci G; Seto J; Callado LF; Neve RL; Milligan G; Sealfon SC; López-Giménez JF; Meana JJ; Benson DL; González-Maeso J
    J Biol Chem; 2012 Dec; 287(53):44301-19. PubMed ID: 23129762
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HDAC2 negatively regulates memory formation and synaptic plasticity.
    Guan JS; Haggarty SJ; Giacometti E; Dannenberg JH; Joseph N; Gao J; Nieland TJ; Zhou Y; Wang X; Mazitschek R; Bradner JE; DePinho RA; Jaenisch R; Tsai LH
    Nature; 2009 May; 459(7243):55-60. PubMed ID: 19424149
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence for the role of metabotropic glutamate (mGlu)2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY404039).
    Fell MJ; Svensson KA; Johnson BG; Schoepp DD
    J Pharmacol Exp Ther; 2008 Jul; 326(1):209-17. PubMed ID: 18424625
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HDAC and HAT inhibitors differently affect analgesia mediated by group II metabotropic glutamate receptors.
    Zammataro M; Sortino MA; Parenti C; Gereau RW; Chiechio S
    Mol Pain; 2014 Nov; 10():68. PubMed ID: 25406541
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape.
    Conte M; Dell'Aversana C; Benedetti R; Petraglia F; Carissimo A; Petrizzi VB; D'Arco AM; Abbondanza C; Nebbioso A; Altucci L
    Oncotarget; 2015 Jan; 6(2):886-901. PubMed ID: 25473896
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of prefrontal cortical 5-HT
    Mitazaki S; Nakagawasai O; Onogi H; Watanabe K; Takahashi K; Tan-No K; Quirion R; Srivastava LK; Tadano T
    Behav Brain Res; 2020 Jan; 377():112226. PubMed ID: 31521737
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inflammation-mediated deacetylation of the ribonuclease 1 promoter
    Bedenbender K; Scheller N; Fischer S; Leiting S; Preissner KT; Schmeck BT; Vollmeister E
    FASEB J; 2019 Aug; 33(8):9017-9029. PubMed ID: 31039328
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.