BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 22869555)

  • 1. Humanization of an anti-CCR4 antibody that kills cutaneous T-cell lymphoma cells and abrogates suppression by T-regulatory cells.
    Chang DK; Sui J; Geng S; Muvaffak A; Bai M; Fuhlbrigge RC; Lo A; Yammanuru A; Hubbard L; Sheehan J; Campbell JJ; Zhu Q; Kupper TS; Marasco WA
    Mol Cancer Ther; 2012 Nov; 11(11):2451-61. PubMed ID: 22869555
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Defucosylated anti-CCR4 monoclonal antibody exercises potent ADCC-mediated antitumor effect in the novel tumor-bearing humanized NOD/Shi-scid, IL-2Rgamma(null) mouse model.
    Ito A; Ishida T; Yano H; Inagaki A; Suzuki S; Sato F; Takino H; Mori F; Ri M; Kusumoto S; Komatsu H; Iida S; Inagaki H; Ueda R
    Cancer Immunol Immunother; 2009 Aug; 58(8):1195-206. PubMed ID: 19048251
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increase in activated Treg in TIL in lung cancer and in vitro depletion of Treg by ADCC using an antihuman CCR4 mAb (KM2760).
    Kurose K; Ohue Y; Sato E; Yamauchi A; Eikawa S; Isobe M; Nishio Y; Uenaka A; Oka M; Nakayama E
    J Thorac Oncol; 2015 Jan; 10(1):74-83. PubMed ID: 25325779
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mogamulizumab and the treatment of CCR4-positive T-cell lymphomas.
    Remer M; Al-Shamkhani A; Glennie M; Johnson P
    Immunotherapy; 2014; 6(11):1187-206. PubMed ID: 25496334
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fully human antagonistic antibodies against CCR4 potently inhibit cell signaling and chemotaxis.
    Hagemann UB; Gunnarsson L; Géraudie S; Scheffler U; Griep RA; Reiersen H; Duncan AR; Kiprijanov SM
    PLoS One; 2014; 9(7):e103776. PubMed ID: 25080123
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Anti-CCR4 mAb and regulatory T cells].
    Kurose K; Ohue Y; Oka M
    Gan To Kagaku Ryoho; 2013 Sep; 40(9):1150-5. PubMed ID: 24047773
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Defucosylated anti-CCR4 monoclonal antibody exerts potent ADCC against primary ATLL cells mediated by autologous human immune cells in NOD/Shi-scid, IL-2R gamma(null) mice in vivo.
    Ito A; Ishida T; Utsunomiya A; Sato F; Mori F; Yano H; Inagaki A; Suzuki S; Takino H; Ri M; Kusumoto S; Komatsu H; Iida S; Inagaki H; Ueda R
    J Immunol; 2009 Oct; 183(7):4782-91. PubMed ID: 19748990
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tumors establish resistance to immunotherapy by regulating T
    Marshall LA; Marubayashi S; Jorapur A; Jacobson S; Zibinsky M; Robles O; Hu DX; Jackson JJ; Pookot D; Sanchez J; Brovarney M; Wadsworth A; Chian D; Wustrow D; Kassner PD; Cutler G; Wong B; Brockstedt DG; Talay O
    J Immunother Cancer; 2020 Nov; 8(2):. PubMed ID: 33243932
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human anti-CCR4 minibody gene transfer for the treatment of cutaneous T-cell lymphoma.
    Han T; Abdel-Motal UM; Chang DK; Sui J; Muvaffak A; Campbell J; Zhu Q; Kupper TS; Marasco WA
    PLoS One; 2012; 7(9):e44455. PubMed ID: 22973452
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CCR4 and its ligands: from bench to bedside.
    Yoshie O; Matsushima K
    Int Immunol; 2015 Jan; 27(1):11-20. PubMed ID: 25087232
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reduction of regulatory T cells by Mogamulizumab, a defucosylated anti-CC chemokine receptor 4 antibody, in patients with aggressive/refractory mycosis fungoides and Sézary syndrome.
    Ni X; Jorgensen JL; Goswami M; Challagundla P; Decker WK; Kim YH; Duvic MA
    Clin Cancer Res; 2015 Jan; 21(2):274-85. PubMed ID: 25376389
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Defucosylated humanized anti-CCR4 monoclonal antibody KW-0761 as a novel immunotherapeutic agent for adult T-cell leukemia/lymphoma.
    Ishii T; Ishida T; Utsunomiya A; Inagaki A; Yano H; Komatsu H; Iida S; Imada K; Uchiyama T; Akinaga S; Shitara K; Ueda R
    Clin Cancer Res; 2010 Mar; 16(5):1520-31. PubMed ID: 20160057
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Anti-CCR4 monoclonal antibody enhances antitumor immunity by modulating tumor-infiltrating Tregs in an ovarian cancer xenograft humanized mouse model.
    Chang DK; Peterson E; Sun J; Goudie C; Drapkin RI; Liu JF; Matulonis U; Zhu Q; Marasco WA
    Oncoimmunology; 2016 Mar; 5(3):e1090075. PubMed ID: 27141347
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Serum CCL22 levels decreased in parallel with disease activity in CCR4-positive mycosis fungoides treated with mogamulizumab.
    Ohuchi K; Fujimura T; Lyu C; Amagai R; Muto Y; Aiba S
    Dermatol Ther; 2020 Nov; 33(6):e14099. PubMed ID: 32725764
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Basic and clinical evaluation of anti-CCR4 mAb in cancer immunotherapy].
    Oka M; Kurose K
    Nihon Rinsho; 2017 Feb; 75(2):209-215. PubMed ID: 30562854
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential CCR4 expression and function in cutaneous T-cell lymphoma cell lines.
    Wu CS; Wang ST; Liao CY; Wu MT
    Kaohsiung J Med Sci; 2008 Nov; 24(11):577-90. PubMed ID: 19239991
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The CCR4 as a novel-specific molecular target for immunotherapy in Hodgkin lymphoma.
    Ishida T; Ishii T; Inagaki A; Yano H; Kusumoto S; Ri M; Komatsu H; Iida S; Inagaki H; Ueda R
    Leukemia; 2006 Dec; 20(12):2162-8. PubMed ID: 17039235
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CCR4 in cutaneous T-cell lymphoma: Therapeutic targeting of a pathogenic driver.
    Nicolay JP; Albrecht JD; Alberti-Violetti S; Berti E
    Eur J Immunol; 2021 Jul; 51(7):1660-1671. PubMed ID: 33811642
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans.
    Sugiyama D; Nishikawa H; Maeda Y; Nishioka M; Tanemura A; Katayama I; Ezoe S; Kanakura Y; Sato E; Fukumori Y; Karbach J; Jäger E; Sakaguchi S
    Proc Natl Acad Sci U S A; 2013 Oct; 110(44):17945-50. PubMed ID: 24127572
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Defucosylated chimeric anti-CC chemokine receptor 4 IgG1 with enhanced antibody-dependent cellular cytotoxicity shows potent therapeutic activity to T-cell leukemia and lymphoma.
    Niwa R; Shoji-Hosaka E; Sakurada M; Shinkawa T; Uchida K; Nakamura K; Matsushima K; Ueda R; Hanai N; Shitara K
    Cancer Res; 2004 Mar; 64(6):2127-33. PubMed ID: 15026353
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.