BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 22870275)

  • 1. Crucial role of TSC-22 in preventing the proteasomal degradation of p53 in cervical cancer.
    Yoon CH; Rho SB; Kim ST; Kho S; Park J; Jang IS; Woo S; Kim SS; Lee JH; Lee SH
    PLoS One; 2012; 7(8):e42006. PubMed ID: 22870275
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HPV-mediated nuclear export of HP1γ drives cervical tumorigenesis by downregulation of p53.
    Yi SA; Lee DH; Kim GW; Ryu HW; Park JW; Lee J; Han J; Park JH; Oh H; Lee J; Choi J; Kim HS; Kang HG; Kim DH; Chun KH; You JS; Han JW; Kwon SH
    Cell Death Differ; 2020 Sep; 27(9):2537-2551. PubMed ID: 32203172
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Degradation of p53 by natural variants of the E6 protein of human papillomavirus type 16.
    Yi JW; Jang M; Kim SJ; Kim SS; Rhee JE
    Oncol Rep; 2013 Apr; 29(4):1617-22. PubMed ID: 23404471
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Scaffold protein FHL2 facilitates MDM2-mediated degradation of IER3 to regulate proliferation of cervical cancer cells.
    Jin H; Lee K; Kim YH; Oh HK; Maeng YI; Kim TH; Suh DS; Bae J
    Oncogene; 2016 Sep; 35(39):5106-18. PubMed ID: 26973248
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GRIM-19 disrupts E6/E6AP complex to rescue p53 and induce apoptosis in cervical cancers.
    Zhou Y; Wei Y; Zhu J; Wang Q; Bao L; Ma Y; Chen Y; Feng D; Zhang A; Sun J; Nallar SC; Shen K; Kalvakolanu DV; Xiao W; Ling B
    PLoS One; 2011; 6(7):e22065. PubMed ID: 21765936
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer.
    Wu DW; Lee MC; Wang J; Chen CY; Cheng YW; Lee H
    Oncogene; 2014 Mar; 33(12):1515-26. PubMed ID: 23584477
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6.
    Wang H; Mo P; Ren S; Yan C
    J Biol Chem; 2010 Apr; 285(17):13201-10. PubMed ID: 20167600
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ribosomal L1 domain-containing protein 1 coordinates with HDM2 to negatively regulate p53 in human colorectal Cancer cells.
    Ding L; Zhang Z; Zhao C; Chen L; Chen Z; Zhang J; Liu Y; Nie Y; He Y; Liao K; Zhang X
    J Exp Clin Cancer Res; 2021 Aug; 40(1):245. PubMed ID: 34362424
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Knockdown of HURP inhibits the proliferation of hepacellular carcinoma cells via downregulation of gankyrin and accumulation of p53.
    Kuo TC; Chang PY; Huang SF; Chou CK; Chao CC
    Biochem Pharmacol; 2012 Mar; 83(6):758-68. PubMed ID: 22230478
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation.
    Seo SK; Hwang CS; Choe TB; Hong SI; Yi JY; Hwang SG; Lee HG; Oh ST; Lee YH; Park IC
    Oncotarget; 2015 Sep; 6(28):26528-40. PubMed ID: 25605253
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FKBP25, a novel regulator of the p53 pathway, induces the degradation of MDM2 and activation of p53.
    Ochocka AM; Kampanis P; Nicol S; Allende-Vega N; Cox M; Marcar L; Milne D; Fuller-Pace F; Meek D
    FEBS Lett; 2009 Feb; 583(4):621-6. PubMed ID: 19166840
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HIV-1 Nef promotes ubiquitination and proteasomal degradation of p53 tumor suppressor protein by using E6AP.
    Ali A; Farooqui SR; Rai J; Singh J; Kumar V; Mishra R; Banerjea AC
    Biochem Biophys Res Commun; 2020 Sep; 529(4):1038-1044. PubMed ID: 32819562
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HPV-16 E6 and E7 oncogene expression is downregulated as a result of Mdm2 knockdown.
    Diaz D; Santander MA; Chavez JA
    Int J Oncol; 2012 Jul; 41(1):141-6. PubMed ID: 22504553
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-gingerol in cervical cancer cells.
    Rastogi N; Duggal S; Singh SK; Porwal K; Srivastava VK; Maurya R; Bhatt ML; Mishra DP
    Oncotarget; 2015 Dec; 6(41):43310-25. PubMed ID: 26621832
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclin-dependent kinase 9 promotes cervical cancer development via AKT2/p53 pathway.
    Xu J; Xu S; Fang Y; Chen T; Xie X; Lu W
    IUBMB Life; 2019 Mar; 71(3):347-356. PubMed ID: 30536701
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Withaferin A induces p53-dependent apoptosis by repression of HPV oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cells.
    Munagala R; Kausar H; Munjal C; Gupta RC
    Carcinogenesis; 2011 Nov; 32(11):1697-705. PubMed ID: 21859835
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fn14 overcomes cisplatin resistance of high-grade serous ovarian cancer by promoting Mdm2-mediated p53-R248Q ubiquitination and degradation.
    Wu AY; Gu LY; Cang W; Cheng MX; Wang WJ; Di W; Huang L; Qiu LH
    J Exp Clin Cancer Res; 2019 Apr; 38(1):176. PubMed ID: 31023317
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Quercetin induces G2 phase arrest and apoptosis with the activation of p53 in an E6 expression‑independent manner in HPV‑positive human cervical cancer‑derived cells.
    Clemente-Soto AF; Salas-Vidal E; Milan-Pacheco C; Sánchez-Carranza JN; Peralta-Zaragoza O; González-Maya L
    Mol Med Rep; 2019 Mar; 19(3):2097-2106. PubMed ID: 30664221
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradation.
    Bae S; Jung JH; Kim K; An IS; Kim SY; Lee JH; Park IC; Jin YW; Lee SJ; An S
    FEBS Lett; 2012 Sep; 586(19):3057-63. PubMed ID: 22819825
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Suppression of miR-22, a tumor suppressor in cervical cancer, by human papillomavirus 16 E6 via a p53/miR-22/HDAC6 pathway.
    Wongjampa W; Ekalaksananan T; Chopjitt P; Chuerduangphui J; Kleebkaow P; Patarapadungkit N; Pientong C
    PLoS One; 2018; 13(10):e0206644. PubMed ID: 30379969
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.