186 related articles for article (PubMed ID: 22871662)
1. Chemoselection of allogeneic HSC after murine neonatal transplantation without myeloablation or post-transplant immunosuppression.
Falahati R; Zhang J; Flebbe-Rehwaldt L; Shi Y; Gerson SL; Gaensler KM
Mol Ther; 2012 Nov; 20(11):2180-9. PubMed ID: 22871662
[TBL] [Abstract][Full Text] [Related]
2. Suppression of HLA expression by lentivirus-mediated gene transfer of siRNA cassettes and in vivo chemoselection to enhance hematopoietic stem cell transplantation.
Hacke K; Falahati R; Flebbe-Rehwaldt L; Kasahara N; Gaensler KM
Immunol Res; 2009; 44(1-3):112-26. PubMed ID: 19048410
[TBL] [Abstract][Full Text] [Related]
3. Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow.
Kramer BA; Lemckert FA; Alexander IE; Gunning PW; McCowage GB
J Gene Med; 2006 Sep; 8(9):1071-85. PubMed ID: 16927363
[TBL] [Abstract][Full Text] [Related]
4. Hematopoietic expression of O(6)-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O(6)-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea.
Kreklau EL; Pollok KE; Bailey BJ; Liu N; Hartwell JR; Williams DA; Erickson LC
Mol Cancer Ther; 2003 Dec; 2(12):1321-9. PubMed ID: 14707273
[TBL] [Abstract][Full Text] [Related]
5. Co-expression of MGMT(P140K) and alpha-L-iduronidase in primary hepatocytes from mucopolysaccharidosis type I mice enables efficient selection with metabolic correction.
Wang D; Worsham DN; Pan D
J Gene Med; 2008 Mar; 10(3):249-59. PubMed ID: 18076130
[TBL] [Abstract][Full Text] [Related]
6. Lentiviral transduction of P140K MGMT into human CD34(+) hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG/BCNU and allows selection in vitro.
Zielske SP; Gerson SL
Mol Ther; 2002 Apr; 5(4):381-7. PubMed ID: 11945064
[TBL] [Abstract][Full Text] [Related]
7. In vivo selection of MGMT(P140K) lentivirus-transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning.
Zielske SP; Reese JS; Lingas KT; Donze JR; Gerson SL
J Clin Invest; 2003 Nov; 112(10):1561-70. PubMed ID: 14617757
[TBL] [Abstract][Full Text] [Related]
8. Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene.
Zhao H; Pestina TI; Nasimuzzaman M; Mehta P; Hargrove PW; Persons DA
Blood; 2009 Jun; 113(23):5747-56. PubMed ID: 19365082
[TBL] [Abstract][Full Text] [Related]
9. Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells.
Ragg S; Xu-Welliver M; Bailey J; D'Souza M; Cooper R; Chandra S; Seshadri R; Pegg AE; Williams DA
Cancer Res; 2000 Sep; 60(18):5187-95. PubMed ID: 11016647
[TBL] [Abstract][Full Text] [Related]
10. Thymidine kinase (TK) gene-transduced human lymphocytes can be highly purified, remain fully functional, and are killed efficiently with ganciclovir.
Munshi NC; Govindarajan R; Drake R; Ding LM; Iyer R; Saylors R; Kornbluth J; Marcus S; Chiang Y; Ennist D; Kwak L; Reynolds C; Tricot G; Barlogie B
Blood; 1997 Feb; 89(4):1334-40. PubMed ID: 9028956
[TBL] [Abstract][Full Text] [Related]
11. Methyl-Guanine-Methyl-Transferase Transgenic Bone Marrow Transplantation Allows N,N-bis(2-chloroethyl)-Nitrosourea Driven Donor Mixed-Chimerism Without Graft-Versus-Host Disease, and With Donor-Specific Allograft Tolerance.
Hu M; Kramer B; Zhang GY; Wang YM; Watson D; Howden B; McCowage G; Alexander IE; Gunning P; Alexander SI
Transplantation; 2015 Dec; 99(12):2476-84. PubMed ID: 26177088
[TBL] [Abstract][Full Text] [Related]
12. Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.
Davis BM; Reese JS; Koç ON; Lee K; Schupp JE; Gerson SL
Cancer Res; 1997 Nov; 57(22):5093-9. PubMed ID: 9371508
[TBL] [Abstract][Full Text] [Related]
13. Nuclear-localizing O6-benzylguanine-resistant GFP-MGMT fusion protein as a novel in vivo selection marker.
Choi U; DeRavin SS; Yamashita K; Whiting-Theobald N; Linton GF; Loktionova NA; Pegg AE; Malech HL
Exp Hematol; 2004 Aug; 32(8):709-19. PubMed ID: 15308322
[TBL] [Abstract][Full Text] [Related]
14. G156A MGMT-transduced human mesenchymal stem cells can be selectively enriched by O6-benzylguanine and BCNU.
Lee K; Gerson SL; Maitra B; Koç ON
J Hematother Stem Cell Res; 2001 Oct; 10(5):691-701. PubMed ID: 11672516
[TBL] [Abstract][Full Text] [Related]
15. Molecular mechanism for ganciclovir resistance in human T lymphocytes transduced with retroviral vectors carrying the herpes simplex virus thymidine kinase gene.
Garin MI; Garrett E; Tiberghien P; Apperley JF; Chalmers D; Melo JV; Ferrand C
Blood; 2001 Jan; 97(1):122-9. PubMed ID: 11133751
[TBL] [Abstract][Full Text] [Related]
16. Protection from lethal murine graft-versus-host disease without compromise of alloengraftment using transgenic donor T cells expressing a thymidine kinase suicide gene.
Drobyski WR; Morse HC; Burns WH; Casper JT; Sandford G
Blood; 2001 Apr; 97(8):2506-13. PubMed ID: 11290616
[TBL] [Abstract][Full Text] [Related]
17. In vivo selection of human hematopoietic cells in a xenograft model using combined pharmacologic and genetic manipulations.
Pollok KE; Hartwell JR; Braber A; Cooper RJ; Jansen M; Ragg S; Bailey BJ; Erickson LC; Kreklau EL; Williams DA
Hum Gene Ther; 2003 Dec; 14(18):1703-14. PubMed ID: 14670122
[TBL] [Abstract][Full Text] [Related]
18. In vivo selection of hematopoietic stem cells transduced at a low multiplicity-of-infection with a foamy viral MGMT(P140K) vector.
Cai S; Ernstberger A; Wang H; Bailey BJ; Hartwell JR; Sinn AL; Eckermann O; Linka Y; Goebel WS; Hanenberg H; Pollok KE
Exp Hematol; 2008 Mar; 36(3):283-92. PubMed ID: 18279716
[TBL] [Abstract][Full Text] [Related]
19. F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.
Maier P; Heckmann D; Spier I; Laufs S; Zucknick M; Allgayer H; Fruehauf S; Zeller WJ; Wenz F
Cancer Gene Ther; 2012 Nov; 19(11):802-10. PubMed ID: 23037811
[TBL] [Abstract][Full Text] [Related]
20. In vivo selection of autologous MGMT gene-modified cells following reduced-intensity conditioning with BCNU and temozolomide in the dog model.
Gori JL; Beard BC; Ironside C; Karponi G; Kiem HP
Cancer Gene Ther; 2012 Aug; 19(8):523-9. PubMed ID: 22627392
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]