204 related articles for article (PubMed ID: 22872267)
1. Mouse models of Apert syndrome.
Holmes G
Childs Nerv Syst; 2012 Sep; 28(9):1505-10. PubMed ID: 22872267
[TBL] [Abstract][Full Text] [Related]
2. Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R) mice.
Wang Y; Sun M; Uhlhorn VL; Zhou X; Peter I; Martinez-Abadias N; Hill CA; Percival CJ; Richtsmeier JT; Huso DL; Jabs EW
BMC Dev Biol; 2010 Feb; 10():22. PubMed ID: 20175913
[TBL] [Abstract][Full Text] [Related]
3. A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis.
Yin L; Du X; Li C; Xu X; Chen Z; Su N; Zhao L; Qi H; Li F; Xue J; Yang J; Jin M; Deng C; Chen L
Bone; 2008 Apr; 42(4):631-43. PubMed ID: 18242159
[TBL] [Abstract][Full Text] [Related]
4. The study of abnormal bone development in the Apert syndrome Fgfr2+/S252W mouse using a 3D hydrogel culture model.
Yang F; Wang Y; Zhang Z; Hsu B; Jabs EW; Elisseeff JH
Bone; 2008 Jul; 43(1):55-63. PubMed ID: 18407821
[TBL] [Abstract][Full Text] [Related]
5. Negative autoregulation of fibroblast growth factor receptor 2 expression characterizing cranial development in cases of Apert (P253R mutation) and Pfeiffer (C278F mutation) syndromes and suggesting a basis for differences in their cranial phenotypes.
Britto JA; Moore RL; Evans RD; Hayward RD; Jones BM
J Neurosurg; 2001 Oct; 95(4):660-73. PubMed ID: 11596961
[TBL] [Abstract][Full Text] [Related]
6. Soluble form of FGFR2 with S252W partially prevents craniosynostosis of the apert mouse model.
Morita J; Nakamura M; Kobayashi Y; Deng CX; Funato N; Moriyama K
Dev Dyn; 2014 Apr; 243(4):560-7. PubMed ID: 24259495
[TBL] [Abstract][Full Text] [Related]
7. Dynamic morphological changes in the skulls of mice mimicking human Apert syndrome resulting from gain-of-function mutation of FGFR2 (P253R).
Du X; Weng T; Sun Q; Su N; Chen Z; Qi H; Jin M; Yin L; He Q; Chen L
J Anat; 2010 Aug; 217(2):97-105. PubMed ID: 20557404
[TBL] [Abstract][Full Text] [Related]
8. A soluble form of fibroblast growth factor receptor 2 (FGFR2) with S252W mutation acts as an efficient inhibitor for the enhanced osteoblastic differentiation caused by FGFR2 activation in Apert syndrome.
Tanimoto Y; Yokozeki M; Hiura K; Matsumoto K; Nakanishi H; Matsumoto T; Marie PJ; Moriyama K
J Biol Chem; 2004 Oct; 279(44):45926-34. PubMed ID: 15310757
[TBL] [Abstract][Full Text] [Related]
9. Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis.
Yokota M; Kobayashi Y; Morita J; Suzuki H; Hashimoto Y; Sasaki Y; Akiyoshi K; Moriyama K
PLoS One; 2014; 9(7):e101693. PubMed ID: 25003957
[TBL] [Abstract][Full Text] [Related]
10. From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome.
Martínez-Abadías N; Holmes G; Pankratz T; Wang Y; Zhou X; Jabs EW; Richtsmeier JT
Dis Model Mech; 2013 May; 6(3):768-79. PubMed ID: 23519026
[TBL] [Abstract][Full Text] [Related]
11. FGF/FGFR signaling coordinates skull development by modulating magnitude of morphological integration: evidence from Apert syndrome mouse models.
Martínez-Abadías N; Heuzé Y; Wang Y; Jabs EW; Aldridge K; Richtsmeier JT
PLoS One; 2011; 6(10):e26425. PubMed ID: 22053191
[TBL] [Abstract][Full Text] [Related]
12. Maldevelopment of the submandibular gland in a mouse model of apert syndrome.
Yamaji K; Morita J; Watanabe T; Gunjigake K; Nakatomi M; Shiga M; Ono K; Moriyama K; Kawamoto T
Dev Dyn; 2018 Nov; 247(11):1175-1185. PubMed ID: 30251381
[TBL] [Abstract][Full Text] [Related]
13. The Fgfr2(S252W/+) mutation in mice retards mandible formation and reduces bone mass as in human Apert syndrome.
Zhou X; Pu D; Liu R; Li X; Wen X; Zhang L; Chen L; Deng M; Liu L
Am J Med Genet A; 2013 May; 161A(5):983-92. PubMed ID: 23495007
[TBL] [Abstract][Full Text] [Related]
14. FGFR2 mutation in a patient with Apert syndrome associated with humeroradial synostosis.
Kanauchi Y; Muragaki Y; Ogino T; Takahara M; Tsuchida H; Ishigaki D
Congenit Anom (Kyoto); 2003 Dec; 43(4):302-5. PubMed ID: 15041782
[TBL] [Abstract][Full Text] [Related]
15. Ocular abnormalities in Apert syndrome: genotype/phenotype correlations with fibroblast growth factor receptor type 2 mutations.
Jadico SK; Young DA; Huebner A; Edmond JC; Pollock AN; McDonald-McGinn DM; Li YJ; Zackai EH; Young TL
J AAPOS; 2006 Dec; 10(6):521-7. PubMed ID: 17189145
[TBL] [Abstract][Full Text] [Related]
16. Effects of FGFR Signaling on Cell Proliferation and Differentiation of Apert Dental Cells.
Lu C; Huguley S; Cui C; Cabaniss LB; Waite PD; Sarver DM; Mamaeva OA; MacDougall M
Cells Tissues Organs; 2016; 201(1):26-37. PubMed ID: 26613250
[TBL] [Abstract][Full Text] [Related]
17. Excessive osteoclast activation by osteoblast paracrine factor RANKL is a major cause of the abnormal long bone phenotype in Apert syndrome model mice.
Shin HR; Kim BS; Kim HJ; Yoon H; Kim WJ; Choi JY; Ryoo HM
J Cell Physiol; 2022 Apr; 237(4):2155-2168. PubMed ID: 35048384
[TBL] [Abstract][Full Text] [Related]
18. Apert syndrome mutant FGFR2 and its soluble form reciprocally alter osteogenesis of primary calvarial osteoblasts.
Suzuki H; Suda N; Shiga M; Kobayashi Y; Nakamura M; Iseki S; Moriyama K
J Cell Physiol; 2012 Sep; 227(9):3267-77. PubMed ID: 22105374
[TBL] [Abstract][Full Text] [Related]
19. Deformed Skull Morphology Is Caused by the Combined Effects of the Maldevelopment of Calvarias, Cranial Base and Brain in FGFR2-P253R Mice Mimicking Human Apert Syndrome.
Luo F; Xie Y; Xu W; Huang J; Zhou S; Wang Z; Luo X; Liu M; Chen L; Du X
Int J Biol Sci; 2017; 13(1):32-45. PubMed ID: 28123344
[TBL] [Abstract][Full Text] [Related]
20. Molecular analysis of exons 8, 9 and 10 of the fibroblast growth factor receptor 2 (FGFR2) gene in two families with index cases of Apert Syndrome.
Torres L; Hernández G; Barrera A; Ospina S; Prada R
Colomb Med (Cali); 2015 Sep; 46(3):150-3. PubMed ID: 26600631
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
