BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 22873368)

  • 1. mTor as a potential target for the prevention and treatment of hepatocellular carcinoma.
    Buitrago-Molina LE; Vogel A
    Curr Cancer Drug Targets; 2012 Nov; 12(9):1045-61. PubMed ID: 22873368
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of benzenesulfonamide derivatives as potent PI3K/mTOR dual inhibitors with in vivo efficacies against hepatocellular carcinoma.
    Chen Y; Zhang L; Yang C; Han J; Wang C; Zheng C; Zhou Y; Lv J; Song Y; Zhu J
    Bioorg Med Chem; 2016 Mar; 24(5):957-66. PubMed ID: 26819001
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sustained antitumor activity by co-targeting mTOR and the microtubule with temsirolimus/vinblastine combination in hepatocellular carcinoma.
    Zhou Q; Lui VW; Lau CP; Cheng SH; Ng MH; Cai Y; Chan SL; Yeo W
    Biochem Pharmacol; 2012 May; 83(9):1146-58. PubMed ID: 22285225
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.
    Zhou Q; Lui VW; Yeo W
    Future Oncol; 2011 Oct; 7(10):1149-67. PubMed ID: 21992728
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Research advances in the mammalian target of rapamycin signaling pathway and its inhibitors in treatment of hepatocellular carcinoma].
    Li SZ; Xu F; Sun CQ; Xu P
    Zhonghua Gan Zang Bing Za Zhi; 2018 Jan; 26(1):77-80. PubMed ID: 29804369
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mTOR inhibitor for the treatment of hepatocellular carcinoma.
    Kudo M
    Dig Dis; 2011; 29(3):310-5. PubMed ID: 21829022
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Benchmarking effects of mTOR, PI3K, and dual PI3K/mTOR inhibitors in hepatocellular and renal cell carcinoma models developing resistance to sunitinib and sorafenib.
    Serova M; de Gramont A; Tijeras-Raballand A; Dos Santos C; Riveiro ME; Slimane K; Faivre S; Raymond E
    Cancer Chemother Pharmacol; 2013 May; 71(5):1297-307. PubMed ID: 23479136
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The anti-hepatocellular carcinoma cell activity by a novel mTOR kinase inhibitor CZ415.
    Zhang W; Chen B; Zhang Y; Li K; Hao K; Jiang L; Wang Y; Mou X; Xu X; Wang Z
    Biochem Biophys Res Commun; 2017 Jun; 487(3):494-499. PubMed ID: 28366631
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway: an emerging treatment strategy for squamous cell lung carcinoma.
    Beck JT; Ismail A; Tolomeo C
    Cancer Treat Rev; 2014 Sep; 40(8):980-9. PubMed ID: 25037117
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting the mTOR pathway in hepatocellular carcinoma: current state and future trends.
    Matter MS; Decaens T; Andersen JB; Thorgeirsson SS
    J Hepatol; 2014 Apr; 60(4):855-65. PubMed ID: 24308993
    [TBL] [Abstract][Full Text] [Related]  

  • 11. mTOR in viral hepatitis and hepatocellular carcinoma: function and treatment.
    Wang Z; Jin W; Jin H; Wang X
    Biomed Res Int; 2014; 2014():735672. PubMed ID: 24804240
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma.
    Watari K; Nishitani A; Shibata T; Noda M; Kawahara A; Akiba J; Murakami Y; Yano H; Kuwano M; Ono M
    Oncotarget; 2016 Jul; 7(30):47403-47417. PubMed ID: 27329724
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.
    Zhang DM; Liu JS; Deng LJ; Chen MF; Yiu A; Cao HH; Tian HY; Fung KP; Kurihara H; Pan JX; Ye WC
    Carcinogenesis; 2013 Jun; 34(6):1331-42. PubMed ID: 23393227
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma.
    Pivonello C; Negri M; De Martino MC; Napolitano M; de Angelis C; Provvisiero DP; Cuomo G; Auriemma RS; Simeoli C; Izzo F; Colao A; Hofland LJ; Pivonello R
    Oncotarget; 2016 Mar; 7(9):9718-31. PubMed ID: 26756219
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activity of the mTOR inhibitor RAD001, the dual mTOR and PI3-kinase inhibitor BEZ235 and the PI3-kinase inhibitor BKM120 in hepatocellular carcinoma.
    Kirstein MM; Boukouris AE; Pothiraju D; Buitrago-Molina LE; Marhenke S; Schütt J; Orlik J; Kühnel F; Hegermann J; Manns MP; Vogel A
    Liver Int; 2013 May; 33(5):780-93. PubMed ID: 23489999
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting mTOR pathways in human malignancies.
    Fasolo A; Sessa C
    Curr Pharm Des; 2012; 18(19):2766-77. PubMed ID: 22475451
    [TBL] [Abstract][Full Text] [Related]  

  • 17. mTOR kinase inhibitors as a treatment strategy in hematological malignancies.
    Grzybowska-Izydorczyk O; Smolewski P
    Future Med Chem; 2012 Mar; 4(4):487-504. PubMed ID: 22416776
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The metabolic and toxicological considerations for mTOR inhibitors in the treatment of hepatocarcinoma.
    Ponziani F; Ojetti V; Tortora A; Di Maurizio L; Purchiaroni F; Gasbarrini A
    Expert Opin Drug Metab Toxicol; 2011 Dec; 7(12):1535-46. PubMed ID: 22032293
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway.
    Polivka J; Janku F
    Pharmacol Ther; 2014 May; 142(2):164-75. PubMed ID: 24333502
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Potential Molecular Targeted Therapeutics: Role of PI3-K/Akt/mTOR Inhibition in Cancer.
    Sokolowski KM; Koprowski S; Kunnimalaiyaan S; Balamurugan M; Gamblin TC; Kunnimalaiyaan M
    Anticancer Agents Med Chem; 2016; 16(1):29-37. PubMed ID: 26179270
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.