These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

824 related articles for article (PubMed ID: 22883233)

  • 1. IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.
    Lerner AG; Upton JP; Praveen PV; Ghosh R; Nakagawa Y; Igbaria A; Shen S; Nguyen V; Backes BJ; Heiman M; Heintz N; Greengard P; Hui S; Tang Q; Trusina A; Oakes SA; Papa FR
    Cell Metab; 2012 Aug; 16(2):250-64. PubMed ID: 22883233
    [TBL] [Abstract][Full Text] [Related]  

  • 2. IRE1α inhibition decreased TXNIP/NLRP3 inflammasome activation through miR-17-5p after neonatal hypoxic-ischemic brain injury in rats.
    Chen D; Dixon BJ; Doycheva DM; Li B; Zhang Y; Hu Q; He Y; Guo Z; Nowrangi D; Flores J; Filippov V; Zhang JH; Tang J
    J Neuroinflammation; 2018 Feb; 15(1):32. PubMed ID: 29394934
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nicotinic acetylcholine receptor signaling regulates inositol-requiring enzyme 1α activation to protect β-cells against terminal unfolded protein response under irremediable endoplasmic reticulum stress.
    Ishibashi T; Morita S; Kishimoto S; Uraki S; Takeshima K; Furukawa Y; Inaba H; Ariyasu H; Iwakura H; Furuta H; Nishi M; Papa FR; Akamizu T
    J Diabetes Investig; 2020 Jul; 11(4):801-813. PubMed ID: 31925927
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome.
    Oslowski CM; Hara T; O'Sullivan-Murphy B; Kanekura K; Lu S; Hara M; Ishigaki S; Zhu LJ; Hayashi E; Hui ST; Greiner D; Kaufman RJ; Bortell R; Urano F
    Cell Metab; 2012 Aug; 16(2):265-73. PubMed ID: 22883234
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Baicalin protects AML-12 cells from lipotoxicity via the suppression of ER stress and TXNIP/NLRP3 inflammasome activation.
    Zhang J; Zhang H; Deng X; Zhang Y; Xu K
    Chem Biol Interact; 2017 Dec; 278():189-196. PubMed ID: 29031535
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ask1 gene deletion blocks maternal diabetes-induced endoplasmic reticulum stress in the developing embryo by disrupting the unfolded protein response signalosome.
    Wang F; Wu Y; Gu H; Reece EA; Fang S; Gabbay-Benziv R; Aberdeen G; Yang P
    Diabetes; 2015 Mar; 64(3):973-88. PubMed ID: 25249581
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thioredoxin-1 regulates IRE1α to ameliorate sepsis-induced NLRP3 inflammasome activation and oxidative stress in Raw 264.7 cell.
    Shao R; Lou X; Xue J; Yang Y; Ning D; Chen G; Jiang L
    Immunopharmacol Immunotoxicol; 2023 Jun; 45(3):277-286. PubMed ID: 36263912
    [No Abstract]   [Full Text] [Related]  

  • 8. Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes.
    Szpigel A; Hainault I; Carlier A; Venteclef N; Batto AF; Hajduch E; Bernard C; Ktorza A; Gautier JF; Ferré P; Bourron O; Foufelle F
    Diabetologia; 2018 Feb; 61(2):399-412. PubMed ID: 28988346
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium.
    Zhao Y; Li Q; Zhao W; Li J; Sun Y; Liu K; Liu B; Zhang N
    J Ethnopharmacol; 2015 Jul; 169():210-8. PubMed ID: 25922268
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bax inhibitor-1 protects from nonalcoholic steatohepatitis by limiting inositol-requiring enzyme 1 alpha signaling in mice.
    Lebeaupin C; Vallée D; Rousseau D; Patouraux S; Bonnafous S; Adam G; Luciano F; Luci C; Anty R; Iannelli A; Marchetti S; Kroemer G; Lacas-Gervais S; Tran A; Gual P; Bailly-Maitre B
    Hepatology; 2018 Aug; 68(2):515-532. PubMed ID: 29457838
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bax Inhibitor-1 preserves pancreatic β-cell proteostasis by limiting proinsulin misfolding and programmed cell death.
    Blanc M; Habbouche L; Xiao P; Lebeaupin C; Janona M; Vaillant N; Irondelle M; Gilleron J; Murcy F; Rousseau D; Luci C; Barouillet T; Marchetti S; Lacas-Gervais S; Yvan-Charvet L; Gual P; Cardozo AK; Bailly-Maitre B
    Cell Death Dis; 2024 May; 15(5):334. PubMed ID: 38744890
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mangiferin inhibits endoplasmic reticulum stress-associated thioredoxin-interacting protein/NLRP3 inflammasome activation with regulation of AMPK in endothelial cells.
    Song J; Li J; Hou F; Wang X; Liu B
    Metabolism; 2015 Mar; 64(3):428-37. PubMed ID: 25499441
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage.
    Bronner DN; Abuaita BH; Chen X; Fitzgerald KA; Nuñez G; He Y; Yin XM; O'Riordan MX
    Immunity; 2015 Sep; 43(3):451-62. PubMed ID: 26341399
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK.
    Li Y; Li J; Li S; Li Y; Wang X; Liu B; Fu Q; Ma S
    Toxicol Appl Pharmacol; 2015 Jul; 286(1):53-63. PubMed ID: 25791922
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endoplasmic reticulum stress related factor IRE1α regulates TXNIP/NLRP3-mediated pyroptosis in diabetic nephropathy.
    Ke R; Wang Y; Hong S; Xiao L
    Exp Cell Res; 2020 Nov; 396(2):112293. PubMed ID: 32950473
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells.
    Robblee MM; Kim CC; Porter Abate J; Valdearcos M; Sandlund KL; Shenoy MK; Volmer R; Iwawaki T; Koliwad SK
    Cell Rep; 2016 Mar; 14(11):2611-23. PubMed ID: 26971994
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Vascular endothelial cells senescence is associated with NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation via reactive oxygen species (ROS)/thioredoxin-interacting protein (TXNIP) pathway.
    Yin Y; Zhou Z; Liu W; Chang Q; Sun G; Dai Y
    Int J Biochem Cell Biol; 2017 Mar; 84():22-34. PubMed ID: 28064010
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Txnip mediates glucocorticoid-activated NLRP3 inflammatory signaling in mouse microglia.
    Bharti V; Tan H; Zhou H; Wang JF
    Neurochem Int; 2019 Dec; 131():104564. PubMed ID: 31586460
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting the TXNIP-NLRP3 interaction with PSSM1443 to suppress inflammation in sepsis-induced myocardial dysfunction.
    Wang L; Zhao H; Xu H; Liu X; Chen X; Peng Q; Xiao M
    J Cell Physiol; 2021 Jun; 236(6):4625-4639. PubMed ID: 33452697
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FXR Inhibits Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome in Hepatocytes and Ameliorates Liver Injury.
    Han CY; Rho HS; Kim A; Kim TH; Jang K; Jun DW; Kim JW; Kim B; Kim SG
    Cell Rep; 2018 Sep; 24(11):2985-2999. PubMed ID: 30208322
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 42.