209 related articles for article (PubMed ID: 22890420)
1. Stimulation of the retinoid X receptor facilitates beta-amyloid clearance across the blood-brain barrier.
Bachmeier C; Beaulieu-Abdelahad D; Crawford F; Mullan M; Paris D
J Mol Neurosci; 2013 Feb; 49(2):270-6. PubMed ID: 22890420
[TBL] [Abstract][Full Text] [Related]
2. Bexarotene Promotes Cholesterol Efflux and Restricts Apical-to-Basolateral Transport of Amyloid-β Peptides in an In Vitro Model of the Human Blood-Brain Barrier.
Kuntz M; Candela P; Saint-Pol J; Lamartinière Y; Boucau MC; Sevin E; Fenart L; Gosselet F
J Alzheimers Dis; 2015; 48(3):849-62. PubMed ID: 26402114
[TBL] [Abstract][Full Text] [Related]
3. ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models.
Cramer PE; Cirrito JR; Wesson DW; Lee CY; Karlo JC; Zinn AE; Casali BT; Restivo JL; Goebel WD; James MJ; Brunden KR; Wilson DA; Landreth GE
Science; 2012 Mar; 335(6075):1503-6. PubMed ID: 22323736
[TBL] [Abstract][Full Text] [Related]
4. Amyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo.
Tai LM; Koster KP; Luo J; Lee SH; Wang YT; Collins NC; Ben Aissa M; Thatcher GRJ; LaDu MJ
J Biol Chem; 2014 Oct; 289(44):30538-30555. PubMed ID: 25217640
[TBL] [Abstract][Full Text] [Related]
5. Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
Fanaee-Danesh E; Gali CC; Tadic J; Zandl-Lang M; Carmen Kober A; Agujetas VR; de Dios C; Tam-Amersdorfer C; Stracke A; Albrecher NM; Manavalan APC; Reiter M; Sun Y; Colell A; Madeo F; Malle E; Panzenboeck U
Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2224-2245. PubMed ID: 31055081
[TBL] [Abstract][Full Text] [Related]
6. A multifaceted role for apoE in the clearance of beta-amyloid across the blood-brain barrier.
Bachmeier C; Paris D; Beaulieu-Abdelahad D; Mouzon B; Mullan M; Crawford F
Neurodegener Dis; 2013; 11(1):13-21. PubMed ID: 22572854
[TBL] [Abstract][Full Text] [Related]
7. ABCA1 is Necessary for Bexarotene-Mediated Clearance of Soluble Amyloid Beta from the Hippocampus of APP/PS1 Mice.
Corona AW; Kodoma N; Casali BT; Landreth GE
J Neuroimmune Pharmacol; 2016 Mar; 11(1):61-72. PubMed ID: 26175148
[TBL] [Abstract][Full Text] [Related]
8. RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment.
Lefterov I; Schug J; Mounier A; Nam KN; Fitz NF; Koldamova R
Neurobiol Dis; 2015 Oct; 82():132-140. PubMed ID: 26071899
[TBL] [Abstract][Full Text] [Related]
9. Role of the cannabinoid system in the transit of beta-amyloid across the blood-brain barrier.
Bachmeier C; Beaulieu-Abdelahad D; Mullan M; Paris D
Mol Cell Neurosci; 2013 Sep; 56():255-62. PubMed ID: 23831388
[TBL] [Abstract][Full Text] [Related]
10. Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.
Zhao J; Fu Y; Liu CC; Shinohara M; Nielsen HM; Dong Q; Kanekiyo T; Bu G
J Biol Chem; 2014 Apr; 289(16):11282-11292. PubMed ID: 24599963
[TBL] [Abstract][Full Text] [Related]
11. Influence of Matrix Metallopeptidase 9 on Beta-Amyloid Elimination Across the Blood-Brain Barrier.
Shackleton B; Ringland C; Abdullah L; Mullan M; Crawford F; Bachmeier C
Mol Neurobiol; 2019 Dec; 56(12):8296-8305. PubMed ID: 31209784
[TBL] [Abstract][Full Text] [Related]
12. Possible Molecular Interactions of Bexarotene - A Retinoid Drug and Alzheimer's Aβ Peptide: A Docking Study.
Mirza Z; Beg MA
Curr Alzheimer Res; 2017; 14(3):327-334. PubMed ID: 27842487
[TBL] [Abstract][Full Text] [Related]
13. Selective dihydropyiridine compounds facilitate the clearance of β-amyloid across the blood-brain barrier.
Bachmeier C; Beaulieu-Abdelahad D; Mullan M; Paris D
Eur J Pharmacol; 2011 Jun; 659(2-3):124-9. PubMed ID: 21497592
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
Shackleton B; Crawford F; Bachmeier C
Fluids Barriers CNS; 2016 Aug; 13(1):14. PubMed ID: 27503326
[TBL] [Abstract][Full Text] [Related]
15. Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system.
Bell RD; Sagare AP; Friedman AE; Bedi GS; Holtzman DM; Deane R; Zlokovic BV
J Cereb Blood Flow Metab; 2007 May; 27(5):909-18. PubMed ID: 17077814
[TBL] [Abstract][Full Text] [Related]
16. Reversal of apoE4-driven brain pathology and behavioral deficits by bexarotene.
Boehm-Cagan A; Michaelson DM
J Neurosci; 2014 May; 34(21):7293-301. PubMed ID: 24849361
[TBL] [Abstract][Full Text] [Related]
17. RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers.
Nam KN; Mounier A; Fitz NF; Wolfe C; Schug J; Lefterov I; Koldamova R
Sci Rep; 2016 Apr; 6():24048. PubMed ID: 27051978
[TBL] [Abstract][Full Text] [Related]
18. Oleocanthal enhances amyloid-β clearance from the brains of TgSwDI mice and in vitro across a human blood-brain barrier model.
Qosa H; Batarseh YS; Mohyeldin MM; El Sayed KA; Keller JN; Kaddoumi A
ACS Chem Neurosci; 2015 Nov; 6(11):1849-59. PubMed ID: 26348065
[TBL] [Abstract][Full Text] [Related]
19. Bexarotene Modulates Retinoid-X-Receptor Expression and Is Protective Against Neurotoxic Endoplasmic Reticulum Stress Response and Apoptotic Pathway Activation.
Dheer Y; Chitranshi N; Gupta V; Abbasi M; Mirzaei M; You Y; Chung R; Graham SL; Gupta V
Mol Neurobiol; 2018 Dec; 55(12):9043-9056. PubMed ID: 29637440
[TBL] [Abstract][Full Text] [Related]
20. Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.
Zhao Z; Sagare AP; Ma Q; Halliday MR; Kong P; Kisler K; Winkler EA; Ramanathan A; Kanekiyo T; Bu G; Owens NC; Rege SV; Si G; Ahuja A; Zhu D; Miller CA; Schneider JA; Maeda M; Maeda T; Sugawara T; Ichida JK; Zlokovic BV
Nat Neurosci; 2015 Jul; 18(7):978-87. PubMed ID: 26005850
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]