BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 22890883)

  • 1. 2-Aminopyridine derivatives as potential σ(2) receptor antagonists.
    Abate C; Ferorelli S; Niso M; Lovicario C; Infantino V; Convertini P; Perrone R; Berardi F
    ChemMedChem; 2012 Oct; 7(10):1847-57. PubMed ID: 22890883
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28).
    Berardi F; Abate C; Ferorelli S; Uricchio V; Colabufo NA; Niso M; Perrone R
    J Med Chem; 2009 Dec; 52(23):7817-28. PubMed ID: 19842660
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of σ receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines.
    Niso M; Abate C; Ferorelli S; Cassano G; Gasparre G; Perrone R; Berardi F
    Bioorg Med Chem; 2013 Apr; 21(7):1865-9. PubMed ID: 23415062
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel derivatives of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with improved fluorescent and σ receptors binding properties.
    Abate C; Niso M; Marottoli R; Riganti C; Ghigo D; Ferorelli S; Ossato G; Perrone R; Lacivita E; Lamb DC; Berardi F
    J Med Chem; 2014 Apr; 57(8):3314-23. PubMed ID: 24697311
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
    Berardi F; Colabufo NA; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
    J Med Chem; 1996 Jan; 39(1):176-82. PubMed ID: 8568804
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analogues of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with added polar functionality and reduced lipophilicity for potential use as positron emission tomography radiotracers.
    Abate C; Niso M; Lacivita E; Mosier PD; Toscano A; Perrone R
    J Med Chem; 2011 Feb; 54(4):1022-32. PubMed ID: 21229979
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity.
    Berardi F; Ferorelli S; Abate C; Colabufo NA; Contino M; Perrone R; Tortorella V
    J Med Chem; 2004 Apr; 47(9):2308-17. PubMed ID: 15084129
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and in vitro Evaluation of Novel Indole-Based Sigma Receptors Ligands.
    Yarim M; Koksal M; Schepmann D; Wünsch B
    Chem Biol Drug Des; 2011 Nov; 78(5):869-75. PubMed ID: 21848665
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The sigma-1 receptor antagonist PB212 reduces the Ca²⁺-release through the inositol (1, 4, 5)-trisphosphate receptor in SK-N-SH cells.
    Gasparre G; Abate C; Berardi F; Cassano G
    Eur J Pharmacol; 2012 Jun; 684(1-3):59-63. PubMed ID: 22465185
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Arylamides hybrids of two high-affinity σ2 receptor ligands as tools for the development of PET radiotracers.
    Abate C; Ferorelli S; Contino M; Marottoli R; Colabufo NA; Perrone R; Berardi F
    Eur J Med Chem; 2011 Sep; 46(9):4733-41. PubMed ID: 21684636
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Δ(8)-Δ(7) sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity.
    Abate C; Niso M; Contino M; Colabufo NA; Ferorelli S; Perrone R; Berardi F
    ChemMedChem; 2011 Jan; 6(1):73-80. PubMed ID: 21069657
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer.
    Pati ML; Hornick JR; Niso M; Berardi F; Spitzer D; Abate C; Hawkins W
    BMC Cancer; 2017 Jan; 17(1):51. PubMed ID: 28086830
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel highly potent and selective sigma 1 receptor antagonists related to spipethiane.
    Piergentili A; Amantini C; Del Bello F; Giannella M; Mattioli L; Palmery M; Perfumi M; Pigini M; Santoni G; Tucci P; Zotti M; Quaglia W
    J Med Chem; 2010 Feb; 53(3):1261-9. PubMed ID: 20067271
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction of the sigma(2) receptor ligand PB28 with the human nucleosome: computational and experimental probes of interaction with the H2A/H2B dimer.
    Abate C; Elenewski J; Niso M; Berardi F; Colabufo NA; Azzariti A; Perrone R; Glennon RA
    ChemMedChem; 2010 Feb; 5(2):268-73. PubMed ID: 20077462
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 (sigma1) and sigma-2 (sigma2) receptor ligands: a review.
    Berardi F; Abate C; Ferorelli S; Colabufo NA; Perrone R
    Cent Nerv Syst Agents Med Chem; 2009 Sep; 9(3):205-19. PubMed ID: 20021355
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of novel N,N'-disubstituted piperazines as sigma receptor ligands.
    Zhang Y; Williams W; Torrence-Campbell C; Bowen WD; Rice KC
    J Med Chem; 1998 Dec; 41(25):4950-7. PubMed ID: 9836612
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives.
    Berardi F; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
    J Med Chem; 1996 Oct; 39(21):4255-60. PubMed ID: 8863803
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fluorescent derivatives of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) as a tool for uptake and cellular localization studies in pancreatic tumor cells.
    Abate C; Hornick JR; Spitzer D; Hawkins WG; Niso M; Perrone R; Berardi F
    J Med Chem; 2011 Aug; 54(16):5858-67. PubMed ID: 21744858
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [3H]RS-23597-190, a potent 5-hydroxytryptamine4 antagonist labels sigma-1 but not sigma-2 binding sites in guinea pig brain.
    Bonhaus DW; Loury DN; Jakeman LB; Hsu SA; To ZP; Leung E; Zeitung KD; Eglen RM; Wong EH
    J Pharmacol Exp Ther; 1994 Oct; 271(1):484-93. PubMed ID: 7965749
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma(1) receptor.
    Berardi F; Ferorelli S; Abate C; Pedone MP; Colabufo NA; Contino M; Perrone R
    J Med Chem; 2005 Dec; 48(26):8237-44. PubMed ID: 16366605
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.