168 related articles for article (PubMed ID: 22892246)
21. Dynamics of Abeta turnover and deposition in different beta-amyloid precursor protein transgenic mouse models following gamma-secretase inhibition.
Abramowski D; Wiederhold KH; Furrer U; Jaton AL; Neuenschwander A; Runser MJ; Danner S; Reichwald J; Ammaturo D; Staab D; Stoeckli M; Rueeger H; Neumann U; Staufenbiel M
J Pharmacol Exp Ther; 2008 Nov; 327(2):411-24. PubMed ID: 18687920
[TBL] [Abstract][Full Text] [Related]
22. Intracellular amyloid-β accumulation in calcium-binding protein-deficient neurons leads to amyloid-β plaque formation in animal model of Alzheimer's disease.
Moon M; Hong HS; Nam DW; Baik SH; Song H; Kook SY; Kim YS; Lee J; Mook-Jung I
J Alzheimers Dis; 2012; 29(3):615-28. PubMed ID: 22269161
[TBL] [Abstract][Full Text] [Related]
23. Immunotherapy against APP beta-secretase cleavage site improves cognitive function and reduces neuroinflammation in Tg2576 mice without a significant effect on brain abeta levels.
Rakover I; Arbel M; Solomon B
Neurodegener Dis; 2007; 4(5):392-402. PubMed ID: 17536186
[TBL] [Abstract][Full Text] [Related]
24. Proteomic analysis of the brain tissues from a transgenic mouse model of amyloid β oligomers.
Takano M; Maekura K; Otani M; Sano K; Nakamura-Hirota T; Tokuyama S; Min KS; Tomiyama T; Mori H; Matsuyama S
Neurochem Int; 2012 Aug; 61(3):347-55. PubMed ID: 22634250
[TBL] [Abstract][Full Text] [Related]
25. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease.
Bard F; Cannon C; Barbour R; Burke RL; Games D; Grajeda H; Guido T; Hu K; Huang J; Johnson-Wood K; Khan K; Kholodenko D; Lee M; Lieberburg I; Motter R; Nguyen M; Soriano F; Vasquez N; Weiss K; Welch B; Seubert P; Schenk D; Yednock T
Nat Med; 2000 Aug; 6(8):916-9. PubMed ID: 10932230
[TBL] [Abstract][Full Text] [Related]
26. Dynamics of {beta}-amyloid reductions in brain, cerebrospinal fluid, and plasma of {beta}-amyloid precursor protein transgenic mice treated with a {gamma}-secretase inhibitor.
Barten DM; Guss VL; Corsa JA; Loo A; Hansel SB; Zheng M; Munoz B; Srinivasan K; Wang B; Robertson BJ; Polson CT; Wang J; Roberts SB; Hendrick JP; Anderson JJ; Loy JK; Denton R; Verdoorn TA; Smith DW; Felsenstein KM
J Pharmacol Exp Ther; 2005 Feb; 312(2):635-43. PubMed ID: 15452193
[TBL] [Abstract][Full Text] [Related]
27. In vivo detection of amyloid plaques in the mouse brain using the near-infrared fluorescence probe THK-265.
Okamura N; Mori M; Furumoto S; Yoshikawa T; Harada R; Ito S; Fujikawa Y; Arai H; Yanai K; Kudo Y
J Alzheimers Dis; 2011; 23(1):37-48. PubMed ID: 20930313
[TBL] [Abstract][Full Text] [Related]
28. A novel transgenic rat model with a full Alzheimer's-like amyloid pathology displays pre-plaque intracellular amyloid-beta-associated cognitive impairment.
Leon WC; Canneva F; Partridge V; Allard S; Ferretti MT; DeWilde A; Vercauteren F; Atifeh R; Ducatenzeiler A; Klein W; Szyf M; Alhonen L; Cuello AC
J Alzheimers Dis; 2010; 20(1):113-26. PubMed ID: 20164597
[TBL] [Abstract][Full Text] [Related]
29. Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology.
Bard F; Barbour R; Cannon C; Carretto R; Fox M; Games D; Guido T; Hoenow K; Hu K; Johnson-Wood K; Khan K; Kholodenko D; Lee C; Lee M; Motter R; Nguyen M; Reed A; Schenk D; Tang P; Vasquez N; Seubert P; Yednock T
Proc Natl Acad Sci U S A; 2003 Feb; 100(4):2023-8. PubMed ID: 12566568
[TBL] [Abstract][Full Text] [Related]
30. Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576.
Chauhan NB; Siegel GJ
J Neurosci Res; 2003 Oct; 74(1):142-7. PubMed ID: 13130516
[TBL] [Abstract][Full Text] [Related]
31. An amyloid-beta protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease.
Lord A; Gumucio A; Englund H; Sehlin D; Sundquist VS; Söderberg L; Möller C; Gellerfors P; Lannfelt L; Pettersson FE; Nilsson LN
Neurobiol Dis; 2009 Dec; 36(3):425-34. PubMed ID: 19703562
[TBL] [Abstract][Full Text] [Related]
32. Amyloid neuropathology in the single Arctic APP transgenic model affects interconnected brain regions.
Rönnbäck A; Sagelius H; Bergstedt KD; Näslund J; Westermark GT; Winblad B; Graff C
Neurobiol Aging; 2012 Apr; 33(4):831.e11-9. PubMed ID: 21880397
[TBL] [Abstract][Full Text] [Related]
33. Chronic Verubecestat Treatment Suppresses Amyloid Accumulation in Advanced Aged Tg2576-AβPPswe Mice Without Inducing Microhemorrhage.
Villarreal S; Zhao F; Hyde LA; Holder D; Forest T; Sondey M; Chen X; Sur C; Parker EM; Kennedy ME
J Alzheimers Dis; 2017; 59(4):1393-1413. PubMed ID: 28800329
[TBL] [Abstract][Full Text] [Related]
34. Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes.
Kurt MA; Davies DC; Kidd M; Duff K; Rolph SC; Jennings KH; Howlett DR
Exp Neurol; 2001 Sep; 171(1):59-71. PubMed ID: 11520121
[TBL] [Abstract][Full Text] [Related]
35. Synaptic transmission is impaired prior to plaque formation in amyloid precursor protein-overexpressing mice without altering behaviorally-correlated sharp wave-ripple complexes.
Hermann D; Both M; Ebert U; Gross G; Schoemaker H; Draguhn A; Wicke K; Nimmrich V
Neuroscience; 2009 Sep; 162(4):1081-90. PubMed ID: 19477243
[TBL] [Abstract][Full Text] [Related]
36. Clioquinol reduces zinc accumulation in neuritic plaques and inhibits the amyloidogenic pathway in AβPP/PS1 transgenic mouse brain.
Wang T; Wang CY; Shan ZY; Teng WP; Wang ZY
J Alzheimers Dis; 2012; 29(3):549-59. PubMed ID: 22269164
[TBL] [Abstract][Full Text] [Related]
37. Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer's disease-like pathology.
Gnoth K; Piechotta A; Kleinschmidt M; Konrath S; Schenk M; Taudte N; Ramsbeck D; Rieckmann V; Geissler S; Eichentopf R; Barendrecht S; Hartlage-Rübsamen M; Demuth HU; Roßner S; Cynis H; Rahfeld JU; Schilling S
Alzheimers Res Ther; 2020 Nov; 12(1):149. PubMed ID: 33189132
[TBL] [Abstract][Full Text] [Related]
38. Specific uptake of an amyloid-β protofibril-binding antibody-tracer in AβPP transgenic mouse brain.
Magnusson K; Sehlin D; Syvänen S; Svedberg MM; Philipson O; Söderberg L; Tegerstedt K; Holmquist M; Gellerfors P; Tolmachev V; Antoni G; Lannfelt L; Hall H; Nilsson LN
J Alzheimers Dis; 2013; 37(1):29-40. PubMed ID: 23780660
[TBL] [Abstract][Full Text] [Related]
39. Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: implications for the pathogenesis and treatment of Alzheimer's disease.
Monsonego A; Maron R; Zota V; Selkoe DJ; Weiner HL
Proc Natl Acad Sci U S A; 2001 Aug; 98(18):10273-8. PubMed ID: 11517335
[TBL] [Abstract][Full Text] [Related]
40. Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice.
Santuccione AC; Merlini M; Shetty A; Tackenberg C; Bali J; Ferretti MT; McAfoose J; Kulic L; Bernreuther C; Welt T; Grimm J; Glatzel M; Rajendran L; Hock C; Nitsch RM
Mol Psychiatry; 2013 Mar; 18(3):358-68. PubMed ID: 22688190
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
