441 related articles for article (PubMed ID: 22898602)
1. Targeting oncogenic Ras signaling in hematologic malignancies.
Ward AF; Braun BS; Shannon KM
Blood; 2012 Oct; 120(17):3397-406. PubMed ID: 22898602
[TBL] [Abstract][Full Text] [Related]
2. Mechanistic and Preclinical Insights from Mouse Models of Hematologic Cancer Characterized by Hyperactive Ras.
Wandler A; Shannon K
Cold Spring Harb Perspect Med; 2018 Apr; 8(4):. PubMed ID: 28778967
[No Abstract] [Full Text] [Related]
3. Targeting the RAS-dependent chemoresistance: The Warburg connection.
Serna-Blasco R; Sanz-Álvarez M; Aguilera Ó; García-Foncillas J
Semin Cancer Biol; 2019 Feb; 54():80-90. PubMed ID: 29432815
[TBL] [Abstract][Full Text] [Related]
4. Challenges in Ras therapeutics in pancreatic cancer.
Choi M; Bien H; Mofunanya A; Powers S
Semin Cancer Biol; 2019 Feb; 54():101-108. PubMed ID: 29170065
[TBL] [Abstract][Full Text] [Related]
5. Drugging the Undruggable: Advances on RAS Targeting in Cancer.
Molina-Arcas M; Samani A; Downward J
Genes (Basel); 2021 Jun; 12(6):. PubMed ID: 34200676
[TBL] [Abstract][Full Text] [Related]
6. Ras processing as a therapeutic target in hematologic malignancies.
Le DT; Shannon KM
Curr Opin Hematol; 2002 Jul; 9(4):308-15. PubMed ID: 12042705
[TBL] [Abstract][Full Text] [Related]
7. A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors.
Loboda A; Nebozhyn M; Klinghoffer R; Frazier J; Chastain M; Arthur W; Roberts B; Zhang T; Chenard M; Haines B; Andersen J; Nagashima K; Paweletz C; Lynch B; Feldman I; Dai H; Huang P; Watters J
BMC Med Genomics; 2010 Jun; 3():26. PubMed ID: 20591134
[TBL] [Abstract][Full Text] [Related]
8. RAS-mediated oncogenic signaling pathways in human malignancies.
Khan AQ; Kuttikrishnan S; Siveen KS; Prabhu KS; Shanmugakonar M; Al-Naemi HA; Haris M; Dermime S; Uddin S
Semin Cancer Biol; 2019 Feb; 54():1-13. PubMed ID: 29524560
[TBL] [Abstract][Full Text] [Related]
9. Mutations in tyrosine kinase and tyrosine phosphatase and their relevance to the target therapy in hematologic malignancies.
Zhu N; Xiao H; Wang LM; Fu S; Zhao C; Huang H
Future Oncol; 2015; 11(4):659-73. PubMed ID: 25686120
[TBL] [Abstract][Full Text] [Related]
10. Tailoring Ras-pathway--inhibitor combinations for cancer therapy.
Blum R; Kloog Y
Drug Resist Updat; 2005 Dec; 8(6):369-80. PubMed ID: 16356760
[TBL] [Abstract][Full Text] [Related]
11. Approaches to Ras signaling modulation and treatment of Ras-dependent disorders: a patent review (2007--present).
Sacco E; Spinelli M; Vanoni M
Expert Opin Ther Pat; 2012 Nov; 22(11):1263-87. PubMed ID: 23009088
[TBL] [Abstract][Full Text] [Related]
12. Improving Prospects for Targeting RAS.
Singh H; Longo DL; Chabner BA
J Clin Oncol; 2015 Nov; 33(31):3650-9. PubMed ID: 26371146
[TBL] [Abstract][Full Text] [Related]
13. Targeting the Ras signaling pathway: a rational, mechanism-based treatment for hematologic malignancies?
Reuter CW; Morgan MA; Bergmann L
Blood; 2000 Sep; 96(5):1655-69. PubMed ID: 10961860
[TBL] [Abstract][Full Text] [Related]
14. PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies.
De Raedt T; Beert E; Pasmant E; Luscan A; Brems H; Ortonne N; Helin K; Hornick JL; Mautner V; Kehrer-Sawatzki H; Clapp W; Bradner J; Vidaud M; Upadhyaya M; Legius E; Cichowski K
Nature; 2014 Oct; 514(7521):247-51. PubMed ID: 25119042
[TBL] [Abstract][Full Text] [Related]
15. The Ras inhibitor farnesylthiosalicylic acid as a potential therapy for neurofibromatosis type 1.
Barkan B; Starinsky S; Friedman E; Stein R; Kloog Y
Clin Cancer Res; 2006 Sep; 12(18):5533-42. PubMed ID: 17000690
[TBL] [Abstract][Full Text] [Related]
16. Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor.
Cichowski K; Santiago S; Jardim M; Johnson BW; Jacks T
Genes Dev; 2003 Feb; 17(4):449-54. PubMed ID: 12600938
[TBL] [Abstract][Full Text] [Related]
17. The role of wild type RAS isoforms in cancer.
Zhou B; Der CJ; Cox AD
Semin Cell Dev Biol; 2016 Oct; 58():60-9. PubMed ID: 27422332
[TBL] [Abstract][Full Text] [Related]
18. How to make an undruggable enzyme druggable: lessons from ras proteins.
Sayyed-Ahmad A; Gorfe AA
Adv Protein Chem Struct Biol; 2020; 122():181-202. PubMed ID: 32951811
[TBL] [Abstract][Full Text] [Related]
19. Prospects for personalized medicine with inhibitors targeting the RAS and PI3K pathways.
Lackner MR
Expert Rev Mol Diagn; 2010 Jan; 10(1):75-87. PubMed ID: 20014924
[TBL] [Abstract][Full Text] [Related]
20. Targeting ROR1 identifies new treatment strategies in hematological cancers.
Karvonen H; Niininen W; Murumägi A; Ungureanu D
Biochem Soc Trans; 2017 Apr; 45(2):457-464. PubMed ID: 28408486
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]