BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

400 related articles for article (PubMed ID: 22902621)

  • 1. A novel approach to recovery of function of mutant proteins by slowing down translation.
    Meriin AB; Mense M; Colbert JD; Liang F; Bihler H; Zaarur N; Rock KL; Sherman MY
    J Biol Chem; 2012 Oct; 287(41):34264-72. PubMed ID: 22902621
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Correcting the F508del-CFTR variant by modulating eukaryotic translation initiation factor 3-mediated translation initiation.
    Hutt DM; Loguercio S; Roth DM; Su AI; Balch WE
    J Biol Chem; 2018 Aug; 293(35):13477-13495. PubMed ID: 30006345
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein synthesis. The delicate dance of translation and folding.
    Puglisi JD
    Science; 2015 Apr; 348(6233):399-400. PubMed ID: 25908811
    [No Abstract]   [Full Text] [Related]  

  • 4. Slowing ribosome velocity restores folding and function of mutant CFTR.
    Oliver KE; Rauscher R; Mijnders M; Wang W; Wolpert MJ; Maya J; Sabusap CM; Kesterson RA; Kirk KL; Rab A; Braakman I; Hong JS; Hartman JL; Ignatova Z; Sorscher EJ
    J Clin Invest; 2019 Dec; 129(12):5236-5253. PubMed ID: 31657788
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein folding. Translational tuning optimizes nascent protein folding in cells.
    Kim SJ; Yoon JS; Shishido H; Yang Z; Rooney LA; Barral JM; Skach WR
    Science; 2015 Apr; 348(6233):444-8. PubMed ID: 25908822
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Folding of CFTR is predominantly cotranslational.
    Kleizen B; van Vlijmen T; de Jonge HR; Braakman I
    Mol Cell; 2005 Oct; 20(2):277-87. PubMed ID: 16246729
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Emergent properties of proteostasis in managing cystic fibrosis.
    Balch WE; Roth DM; Hutt DM
    Cold Spring Harb Perspect Biol; 2011 Feb; 3(2):. PubMed ID: 21421917
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Slowing bacterial translation speed enhances eukaryotic protein folding efficiency.
    Siller E; DeZwaan DC; Anderson JF; Freeman BC; Barral JM
    J Mol Biol; 2010 Mar; 396(5):1310-8. PubMed ID: 20043920
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Base treatment corrects defects due to misfolding of mutant cystic fibrosis transmembrane conductance regulator.
    Namkung W; Kim KH; Lee MG
    Gastroenterology; 2005 Dec; 129(6):1979-90. PubMed ID: 16344066
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    Chung WJ; Goeckeler-Fried JL; Havasi V; Chiang A; Rowe SM; Plyler ZE; Hong JS; Mazur M; Piazza GA; Keeton AB; White EL; Rasmussen L; Weissman AM; Denny RA; Brodsky JL; Sorscher EJ
    PLoS One; 2016; 11(10):e0163615. PubMed ID: 27732613
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unravelling druggable signalling networks that control F508del-CFTR proteostasis.
    Hegde RN; Parashuraman S; Iorio F; Ciciriello F; Capuani F; Carissimo A; Carrella D; Belcastro V; Subramanian A; Bounti L; Persico M; Carlile G; Galietta L; Thomas DY; Di Bernardo D; Luini A
    Elife; 2015 Dec; 4():. PubMed ID: 26701908
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The stop-and-go traffic regulating protein biogenesis: How translation kinetics controls proteostasis.
    Stein KC; Frydman J
    J Biol Chem; 2019 Feb; 294(6):2076-2084. PubMed ID: 30504455
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Therapeutic approaches to repair defects in deltaF508 CFTR folding and cellular targeting.
    Powell K; Zeitlin PL
    Adv Drug Deliv Rev; 2002 Dec; 54(11):1395-408. PubMed ID: 12458151
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Probing conformational rescue induced by a chemical corrector of F508del-cystic fibrosis transmembrane conductance regulator (CFTR) mutant.
    Yu W; Kim Chiaw P; Bear CE
    J Biol Chem; 2011 Jul; 286(28):24714-25. PubMed ID: 21602569
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect.
    Veit G; Oliver K; Apaja PM; Perdomo D; Bidaud-Meynard A; Lin ST; Guo J; Icyuz M; Sorscher EJ; Hartman JL; Lukacs GL
    PLoS Biol; 2016 May; 14(5):e1002462. PubMed ID: 27168400
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular dissection of the butyrate action revealed the involvement of mitogen-activated protein kinase in cystic fibrosis transmembrane conductance regulator biogenesis.
    Sugita M; Kongo H; Shiba Y
    Mol Pharmacol; 2004 Nov; 66(5):1248-59. PubMed ID: 15304546
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biosynthesis and degradation of CFTR.
    Kopito RR
    Physiol Rev; 1999 Jan; 79(1 Suppl):S167-73. PubMed ID: 9922380
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Endoplasmic Reticulum-Targeted Subunit Toxins Provide a New Approach to Rescue Misfolded Mutant Proteins and Revert Cell Models of Genetic Diseases.
    Adnan H; Zhang Z; Park HJ; Tailor C; Che C; Kamani M; Spitalny G; Binnington B; Lingwood C
    PLoS One; 2016; 11(12):e0166948. PubMed ID: 27935997
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression and purification of the cystic fibrosis transmembrane conductance regulator protein in Saccharomyces cerevisiae.
    O'Ryan L; Rimington T; Cant N; Ford RC
    J Vis Exp; 2012 Mar; (61):. PubMed ID: 22433465
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Silencing of the Hsp70-specific nucleotide-exchange factor BAG3 corrects the F508del-CFTR variant by restoring autophagy.
    Hutt DM; Mishra SK; Roth DM; Larsen MB; Angles F; Frizzell RA; Balch WE
    J Biol Chem; 2018 Aug; 293(35):13682-13695. PubMed ID: 29986884
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.