BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 22907715)

  • 1. Trimethyl-4-oxo-4,5,6,7-tetrahydroindazole-1-acetic acid: a new lead compound with selective COX-2 inhibitory activity.
    Abdel-Rahman HM; Ozadali K
    Arch Pharm (Weinheim); 2012 Nov; 345(11):878-83. PubMed ID: 22907715
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, biological evaluation, and docking studies of novel heterocyclic diaryl compounds as selective COX-2 inhibitors.
    Eren G; Unlü S; Nuñez MT; Labeaga L; Ledo F; Entrena A; Banoğlu E; Costantino G; Sahin MF
    Bioorg Med Chem; 2010 Sep; 18(17):6367-76. PubMed ID: 20692174
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diarylheterocycle core ring features effect in selective COX-1 inhibition.
    Perrone MG; Vitale P; Malerba P; Altomare A; Rizzi R; Lavecchia A; Di Giovanni C; Novellino E; Scilimati A
    ChemMedChem; 2012 Apr; 7(4):629-41. PubMed ID: 22278975
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors.
    Vitale P; Tacconelli S; Perrone MG; Malerba P; Simone L; Scilimati A; Lavecchia A; Dovizio M; Marcantoni E; Bruno A; Patrignani P
    J Med Chem; 2013 Jun; 56(11):4277-99. PubMed ID: 23651359
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study.
    El-Sayed MA; Abdel-Aziz NI; Abdel-Aziz AA; El-Azab AS; Asiri YA; Eltahir KE
    Bioorg Med Chem; 2011 Jun; 19(11):3416-24. PubMed ID: 21570309
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and biological evaluation of ketoprofen analogs as potent cyclooxygenase-2 inhibitors.
    Zarghi A; Ghodsi R
    Bioorg Med Chem; 2010 Aug; 18(16):5855-60. PubMed ID: 20650641
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design of novel N-phenylnicotinamides as selective cyclooxygenase-1 inhibitors.
    Shi L; Li ZL; Yang Y; Zhu ZW; Zhu HL
    Bioorg Med Chem Lett; 2011 Jan; 21(1):121-4. PubMed ID: 21144750
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of 4,5-diphenyloxazolone derivatives on route towards selective COX-2 inhibitors.
    Dündar Y; Unlü S; Banoğlu E; Entrena A; Costantino G; Nuñez MT; Labeaga L; Sahin MF; Noyanalpan N
    Eur J Med Chem; 2009 May; 44(5):1830-7. PubMed ID: 19084295
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and biological evaluation of new 2,3-diarylquinoline derivatives as selective cyclooxygenase-2 inhibitors.
    Ghodsi R; Zarghi A; Daraei B; Hedayati M
    Bioorg Med Chem; 2010 Feb; 18(3):1029-33. PubMed ID: 20061161
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclooxygenase-1 and cyclooxygenase-2 inhibition of novel 1,2-disubstituted imidazoles.
    Handler N; Jaeger W; Kuen-Krismer B; Erker T
    Arch Pharm (Weinheim); 2005 Dec; 338(12):602-4. PubMed ID: 16353278
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and screening of cyclooxygenase inhibitory activity of some 1,3-dioxoisoindoline derivatives.
    Cizmeciolu M; Pabuguoglu V; Ballar P; Pabuççuoğlu A; Soyer Z
    Arzneimittelforschung; 2011; 61(3):186-90. PubMed ID: 21528644
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation of glycolamide esters of indomethacin as potential cyclooxygenase-2 (COX-2) inhibitors.
    Khanna S; Madan M; Vangoori A; Banerjee R; Thaimattam R; Jafar Sadik Basha SK; Ramesh M; Casturi SR; Pal M
    Bioorg Med Chem; 2006 Jul; 14(14):4820-33. PubMed ID: 16581252
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN; Chen QH; Knaus EE
    J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and biological evaluation of linear 1-(4-, 3- or 2-methylsulfonylphenyl)-2-phenylacetylenes: a novel class of cyclooxygenase-2 inhibitors.
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2005 Dec; 13(23):6425-34. PubMed ID: 16099663
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of 3-alkyl-2-aryl-1,3-thiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors.
    Zebardast T; Zarghi A; Daraie B; Hedayati M; Dadrass OG
    Bioorg Med Chem Lett; 2009 Jun; 19(12):3162-5. PubMed ID: 19447036
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular modeling, synthesis and screening of some new 4-thiazolidinone derivatives with promising selective COX-2 inhibitory activity.
    Unsal-Tan O; Ozadali K; Piskin K; Balkan A
    Eur J Med Chem; 2012 Nov; 57():59-64. PubMed ID: 23047224
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of new 4-carboxyl quinoline derivatives as cyclooxygenase-2 inhibitors.
    Zarghi A; Ghodsi R; Azizi E; Daraie B; Hedayati M; Dadrass OG
    Bioorg Med Chem; 2009 Jul; 17(14):5312-7. PubMed ID: 19560931
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective COX-1 inhibition as a target of theranostic novel diarylisoxazoles.
    Vitale P; Perrone MG; Malerba P; Lavecchia A; Scilimati A
    Eur J Med Chem; 2014 Mar; 74():606-18. PubMed ID: 24531199
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of (E)-1,1,2-triarylethenes: novel inhibitors of the cyclooxygenase-2 (COX-2) isozyme.
    Uddin MJ; Rao PN; McDonald R; Knaus EE
    Bioorg Med Chem Lett; 2005 Jan; 15(2):439-42. PubMed ID: 15603969
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationship.
    Murias M; Handler N; Erker T; Pleban K; Ecker G; Saiko P; Szekeres T; Jäger W
    Bioorg Med Chem; 2004 Nov; 12(21):5571-8. PubMed ID: 15465334
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.