BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

319 related articles for article (PubMed ID: 22912718)

  • 1. Palmitoylation regulates intracellular trafficking of β2 adrenergic receptor/arrestin/phosphodiesterase 4D complexes in cardiomyocytes.
    Liu R; Wang D; Shi Q; Fu Q; Hizon S; Xiang YK
    PLoS One; 2012; 7(8):e42658. PubMed ID: 22912718
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heterologous desensitization of cardiac β-adrenergic signal via hormone-induced βAR/arrestin/PDE4 complexes.
    Shi Q; Li M; Mika D; Fu Q; Kim S; Phan J; Shen A; Vandecasteele G; Xiang YK
    Cardiovasc Res; 2017 May; 113(6):656-670. PubMed ID: 28339772
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells.
    Lynch MJ; Baillie GS; Mohamed A; Li X; Maisonneuve C; Klussmann E; van Heeke G; Houslay MD
    J Biol Chem; 2005 Sep; 280(39):33178-89. PubMed ID: 16030021
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PDE4 and mAKAPβ are nodal organizers of β2-ARs nuclear PKA signalling in cardiac myocytes.
    Bedioune I; Lefebvre F; Lechêne P; Varin A; Domergue V; Kapiloff MS; Fischmeister R; Vandecasteele G
    Cardiovasc Res; 2018 Sep; 114(11):1499-1511. PubMed ID: 29733383
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential association of phosphodiesterase 4D isoforms with beta2-adrenoceptor in cardiac myocytes.
    De Arcangelis V; Liu R; Soto D; Xiang Y
    J Biol Chem; 2009 Dec; 284(49):33824-32. PubMed ID: 19801680
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dynamic protein kinase a activities induced by beta-adrenoceptors dictate signaling propagation for substrate phosphorylation and myocyte contraction.
    Soto D; De Arcangelis V; Zhang J; Xiang Y
    Circ Res; 2009 Mar; 104(6):770-9. PubMed ID: 19213958
    [TBL] [Abstract][Full Text] [Related]  

  • 7. beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi.
    Baillie GS; Sood A; McPhee I; Gall I; Perry SJ; Lefkowitz RJ; Houslay MD
    Proc Natl Acad Sci U S A; 2003 Feb; 100(3):940-5. PubMed ID: 12552097
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A long lasting β1 adrenergic receptor stimulation of cAMP/protein kinase A (PKA) signal in cardiac myocytes.
    Fu Q; Kim S; Soto D; De Arcangelis V; DiPilato L; Liu S; Xu B; Shi Q; Zhang J; Xiang YK
    J Biol Chem; 2014 May; 289(21):14771-81. PubMed ID: 24713698
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy.
    Wang L; Burmeister BT; Johnson KR; Baillie GS; Karginov AV; Skidgel RA; O'Bryan JP; Carnegie GK
    Cell Signal; 2015 May; 27(5):908-22. PubMed ID: 25683917
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphodiesterase-4 influences the PKA phosphorylation status and membrane translocation of G-protein receptor kinase 2 (GRK2) in HEK-293beta2 cells and cardiac myocytes.
    Li X; Huston E; Lynch MJ; Houslay MD; Baillie GS
    Biochem J; 2006 Mar; 394(Pt 2):427-35. PubMed ID: 16356165
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor.
    De Arcangelis V; Soto D; Xiang Y
    Mol Pharmacol; 2008 Nov; 74(5):1453-62. PubMed ID: 18703669
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes.
    Isidori AM; Cornacchione M; Barbagallo F; Di Grazia A; Barrios F; Fassina L; Monaco L; Giannetta E; Gianfrilli D; Garofalo S; Zhang X; Chen X; Xiang YK; Lenzi A; Pellegrini M; Naro F
    Cardiovasc Res; 2015 Jun; 106(3):408-20. PubMed ID: 25852085
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Equilibrium between adenylyl cyclase and phosphodiesterase patterns adrenergic agonist dose-dependent spatiotemporal cAMP/protein kinase A activities in cardiomyocytes.
    De Arcangelis V; Liu S; Zhang D; Soto D; Xiang YK
    Mol Pharmacol; 2010 Sep; 78(3):340-9. PubMed ID: 20530128
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes.
    Haj Slimane Z; Bedioune I; Lechêne P; Varin A; Lefebvre F; Mateo P; Domergue-Dupont V; Dewenter M; Richter W; Conti M; El-Armouche A; Zhang J; Fischmeister R; Vandecasteele G
    Cardiovasc Res; 2014 Apr; 102(1):97-106. PubMed ID: 24550350
    [TBL] [Abstract][Full Text] [Related]  

  • 15. β2-adrenergic receptor-coupled phosphoinositide 3-kinase constrains cAMP-dependent increases in cardiac inotropy through phosphodiesterase 4 activation.
    Gregg CJ; Steppan J; Gonzalez DR; Champion HC; Phan AC; Nyhan D; Shoukas AA; Hare JM; Barouch LA; Berkowitz DE
    Anesth Analg; 2010 Oct; 111(4):870-7. PubMed ID: 20705779
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Beta-arrestin-recruited phosphodiesterase-4 desensitizes the AKAP79/PKA-mediated switching of beta2-adrenoceptor signalling to activation of ERK.
    Houslay MD; Baillie GS
    Biochem Soc Trans; 2005 Dec; 33(Pt 6):1333-6. PubMed ID: 16246112
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Importance of regions outside the cytoplasmic tail of G-protein-coupled receptors for phosphorylation and dephosphorylation.
    Gehret AU; Hinkle PM
    Biochem J; 2010 May; 428(2):235-45. PubMed ID: 20345371
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tyrosine 308 is necessary for ligand-directed Gs protein-biased signaling of β2-adrenoceptor.
    Woo AY; Jozwiak K; Toll L; Tanga MJ; Kozocas JA; Jimenez L; Huang Y; Song Y; Plazinska A; Pajak K; Paul RK; Bernier M; Wainer IW; Xiao RP
    J Biol Chem; 2014 Jul; 289(28):19351-63. PubMed ID: 24831005
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5.
    Bolger GB; Baillie GS; Li X; Lynch MJ; Herzyk P; Mohamed A; Mitchell LH; McCahill A; Hundsrucker C; Klussmann E; Adams DR; Houslay MD
    Biochem J; 2006 Aug; 398(1):23-36. PubMed ID: 16689683
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphatidylinositol 3-kinase offsets cAMP-mediated positive inotropic effect via inhibiting Ca2+ influx in cardiomyocytes.
    Leblais V; Jo SH; Chakir K; Maltsev V; Zheng M; Crow MT; Wang W; Lakatta EG; Xiao RP
    Circ Res; 2004 Dec; 95(12):1183-90. PubMed ID: 15539636
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.