These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

503 related articles for article (PubMed ID: 22915595)

  • 1. Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5.
    Sekine S; Kanamaru Y; Koike M; Nishihara A; Okada M; Kinoshita H; Kamiyama M; Maruyama J; Uchiyama Y; Ishihara N; Takeda K; Ichijo H
    J Biol Chem; 2012 Oct; 287(41):34635-45. PubMed ID: 22915595
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cleavage of mitochondrial homeostasis regulator PGAM5 by the intramembrane protease PARL is governed by transmembrane helix dynamics and oligomeric state.
    Siebert V; Silber M; Heuten E; Muhle-Goll C; Lemberg MK
    J Biol Chem; 2022 Sep; 298(9):102321. PubMed ID: 35921890
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insights into the catalytic properties of the mitochondrial rhomboid protease PARL.
    Lysyk L; Brassard R; Arutyunova E; Siebert V; Jiang Z; Takyi E; Morrison M; Young HS; Lemberg MK; O'Donoghue AJ; Lemieux MJ
    J Biol Chem; 2021; 296():100383. PubMed ID: 33556373
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L.
    Wai T; Saita S; Nolte H; Müller S; König T; Richter-Dennerlein R; Sprenger HG; Madrenas J; Mühlmeister M; Brandt U; Krüger M; Langer T
    EMBO Rep; 2016 Dec; 17(12):1844-1856. PubMed ID: 27737933
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis.
    Yan C; Gong L; Chen L; Xu M; Abou-Hamdan H; Tang M; Désaubry L; Song Z
    Autophagy; 2020 Mar; 16(3):419-434. PubMed ID: 31177901
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Syntaxin 17 regulates the localization and function of PGAM5 in mitochondrial division and mitophagy.
    Sugo M; Kimura H; Arasaki K; Amemiya T; Hirota N; Dohmae N; Imai Y; Inoshita T; Shiba-Fukushima K; Hattori N; Cheng J; Fujimoto T; Wakana Y; Inoue H; Tagaya M
    EMBO J; 2018 Nov; 37(21):. PubMed ID: 30237312
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PARL Protease: A Glimpse at Intramembrane Proteolysis in the Inner Mitochondrial Membrane.
    Lysyk L; Brassard R; Touret N; Lemieux MJ
    J Mol Biol; 2020 Aug; 432(18):5052-5062. PubMed ID: 32320686
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.
    Jin SM; Lazarou M; Wang C; Kane LA; Narendra DP; Youle RJ
    J Cell Biol; 2010 Nov; 191(5):933-42. PubMed ID: 21115803
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Self-regulated cleavage of the mitochondrial intramembrane-cleaving protease PARL yields Pbeta, a nuclear-targeted peptide.
    Sík A; Passer BJ; Koonin EV; Pellegrini L
    J Biol Chem; 2004 Apr; 279(15):15323-9. PubMed ID: 14732705
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chemical Blockage of the Mitochondrial Rhomboid Protease PARL by Novel Ketoamide Inhibitors Reveals Its Role in PINK1/Parkin-Dependent Mitophagy.
    Poláchová E; Bach K; Heuten E; Stanchev S; Tichá A; Lampe P; Majer P; Langer T; Lemberg MK; Stříšovský K
    J Med Chem; 2023 Jan; 66(1):251-265. PubMed ID: 36540942
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking.
    Meissner C; Lorenz H; Weihofen A; Selkoe DJ; Lemberg MK
    J Neurochem; 2011 Jun; 117(5):856-67. PubMed ID: 21426348
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pgam5 released from damaged mitochondria induces mitochondrial biogenesis via Wnt signaling.
    Bernkopf DB; Jalal K; Brückner M; Knaup KX; Gentzel M; Schambony A; Behrens J
    J Cell Biol; 2018 Apr; 217(4):1383-1394. PubMed ID: 29438981
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism.
    Shi G; McQuibban GA
    Cell Rep; 2017 Feb; 18(6):1458-1472. PubMed ID: 28178523
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PINK1 cleavage at position A103 by the mitochondrial protease PARL.
    Deas E; Plun-Favreau H; Gandhi S; Desmond H; Kjaer S; Loh SH; Renton AE; Harvey RJ; Whitworth AJ; Martins LM; Abramov AY; Wood NW
    Hum Mol Genet; 2011 Mar; 20(5):867-79. PubMed ID: 21138942
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria.
    Saita S; Tatsuta T; Lampe PA; König T; Ohba Y; Langer T
    EMBO J; 2018 Feb; 37(4):. PubMed ID: 29301859
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
    Saita S; Nolte H; Fiedler KU; Kashkar H; Venne AS; Zahedi RP; Krüger M; Langer T
    Nat Cell Biol; 2017 Apr; 19(4):318-328. PubMed ID: 28288130
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy.
    Meissner C; Lorenz H; Hehn B; Lemberg MK
    Autophagy; 2015; 11(9):1484-98. PubMed ID: 26101826
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A cut short to death: Parl and Opa1 in the regulation of mitochondrial morphology and apoptosis.
    Pellegrini L; Scorrano L
    Cell Death Differ; 2007 Jul; 14(7):1275-84. PubMed ID: 17464328
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease.
    Shi G; Lee JR; Grimes DA; Racacho L; Ye D; Yang H; Ross OA; Farrer M; McQuibban GA; Bulman DE
    Hum Mol Genet; 2011 May; 20(10):1966-74. PubMed ID: 21355049
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling.
    Cipolat S; Rudka T; Hartmann D; Costa V; Serneels L; Craessaerts K; Metzger K; Frezza C; Annaert W; D'Adamio L; Derks C; Dejaegere T; Pellegrini L; D'Hooge R; Scorrano L; De Strooper B
    Cell; 2006 Jul; 126(1):163-75. PubMed ID: 16839884
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.