These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 22916727)

  • 1. Design and synthesis of indomethacin analogues that inhibit P-glycoprotein and/or multidrug resistant protein without COX inhibitory activity.
    Arisawa M; Kasaya Y; Obata T; Sasaki T; Nakamura T; Araki T; Yamamoto K; Sasaki A; Yamano A; Ito M; Abe H; Ito Y; Shuto S
    J Med Chem; 2012 Sep; 55(18):8152-63. PubMed ID: 22916727
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Atropisomerism observed in indometacin derivatives.
    Takahashi H; Wakamatsu S; Tabata H; Oshitari T; Harada A; Inoue K; Natsugari H
    Org Lett; 2011 Feb; 13(4):760-3. PubMed ID: 21250752
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thiazole analogues of the NSAID indomethacin as selective COX-2 inhibitors.
    Woods KW; McCroskey RW; Michaelides MR; Wada CK; Hulkower KI; Bell RL
    Bioorg Med Chem Lett; 2001 May; 11(10):1325-8. PubMed ID: 11392547
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors.
    Kalgutkar AS; Marnett AB; Crews BC; Remmel RP; Marnett LJ
    J Med Chem; 2000 Jul; 43(15):2860-70. PubMed ID: 10956194
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enhancement of doxorubicin cytotoxicity on human esophageal squamous cell carcinoma cells by indomethacin and 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC236) via inhibiting P-glycoprotein activity.
    Yu L; Wu WK; Li ZJ; Liu QC; Li HT; Wu YC; Cho CH
    Mol Pharmacol; 2009 Jun; 75(6):1364-73. PubMed ID: 19264847
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents.
    Selvam C; Jachak SM; Thilagavathi R; Chakraborti AK
    Bioorg Med Chem Lett; 2005 Apr; 15(7):1793-7. PubMed ID: 15780608
    [TBL] [Abstract][Full Text] [Related]  

  • 7. From indomethacin to a selective COX-2 inhibitor. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors.
    Lau CK; Black WC; Belley M; Chan C; Charleson S; Denis D; Gauthier JY; Gordon R; Guay D; Hamel P; Kargman S; Leblanc Y; Mancini J; Ouellet M; Percival D; Prasit P; Roy P; Skorey K; Tagari P; Vickers P; Wong E
    Adv Exp Med Biol; 1997; 407():73-8. PubMed ID: 9321934
    [No Abstract]   [Full Text] [Related]  

  • 8. Synthesis of indomethacin analogues for evaluation as modulators of MRP activity.
    Maguire AR; Plunkett SJ; Papot S; Clynes M; O'Connor R; Touhey S
    Bioorg Med Chem; 2001 Mar; 9(3):745-62. PubMed ID: 11310610
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Investigations of new pyridazinone derivatives for the synthesis of potent analgesic and anti-inflammatory compounds with cyclooxygenase inhibitory activity.
    Okçelik B; Unlü S; Banoglu E; Küpeli E; Yeşilada E; Sahin MF
    Arch Pharm (Weinheim); 2003 Sep; 336(9):406-12. PubMed ID: 14528488
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Desmethyl derivatives of indomethacin and sulindac as probes for cyclooxygenase-dependent biology.
    Felts AS; Ji C; Stafford JB; Crews BC; Kingsley PJ; Rouzer CA; Washington MK; Subbaramaiah K; Siegel BS; Young SM; Dannenberg AJ; Marnett LJ
    ACS Chem Biol; 2007 Jul; 2(7):479-83. PubMed ID: 17602619
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors.
    Praveen Rao PN; Amini M; Li H; Habeeb AG; Knaus EE
    J Med Chem; 2003 Nov; 46(23):4872-82. PubMed ID: 14584938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modulation of MRP-1-mediated multidrug resistance by indomethacin analogues.
    Rosenbaum C; Röhrs S; Müller O; Waldmann H
    J Med Chem; 2005 Feb; 48(4):1179-87. PubMed ID: 15715484
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cox-2-selective inhibitors: the new super aspirins.
    DeWitt DL
    Mol Pharmacol; 1999 Apr; 55(4):625-31. PubMed ID: 10101019
    [No Abstract]   [Full Text] [Related]  

  • 14. 3-Formylchromones: potential antiinflammatory agents.
    Khan KM; Ambreen N; Mughal UR; Jalil S; Perveen S; Choudhary MI
    Eur J Med Chem; 2010 Sep; 45(9):4058-64. PubMed ID: 20576329
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Quantitative structure activity relationship studies of diaryl furanones as selective COX-2 inhibitors.
    Shahapurkar S; Pandya T; Kawathekar N; Chaturvedi SC
    Eur J Med Chem; 2004 Apr; 39(4):383-8. PubMed ID: 15072847
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
    Velázquez C; Praveen Rao PN; Knaus EE
    J Med Chem; 2005 Jun; 48(12):4061-7. PubMed ID: 15943479
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Covalent modification of cyclooxygenase-2 (COX-2) by 2-acetoxyphenyl alkyl sulfides, a new class of selective COX-2 inactivators.
    Kalgutkar AS; Kozak KR; Crews BC; Hochgesang GP; Marnett LJ
    J Med Chem; 1998 Nov; 41(24):4800-18. PubMed ID: 9822550
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, and biological evaluation of substituted 2-alkylthio-1,5-diarylimidazoles as selective COX-2 inhibitors.
    Navidpour L; Shadnia H; Shafaroodi H; Amini M; Dehpour AR; Shafiee A
    Bioorg Med Chem; 2007 Mar; 15(5):1976-82. PubMed ID: 17258905
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
    Song Y; Connor DT; Doubleday R; Sorenson RJ; Sercel AD; Unangst PC; Roth BD; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
    J Med Chem; 1999 Apr; 42(7):1151-60. PubMed ID: 10197959
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors.
    Kalgutkar AS; Crews BC; Rowlinson SW; Marnett AB; Kozak KR; Remmel RP; Marnett LJ
    Proc Natl Acad Sci U S A; 2000 Jan; 97(2):925-30. PubMed ID: 10639181
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.