BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 22921246)

  • 1. Dependence of the reduction products of platinum(IV) prodrugs upon the configuration of the substrate, bulk of the carrier ligands, and nature of the reducing agent.
    Sinisi M; Intini FP; Natile G
    Inorg Chem; 2012 Sep; 51(18):9694-704. PubMed ID: 22921246
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Importance of platinum(II)-assisted platinum(IV) substitution for the oxidation of guanosine derivatives by platinum(IV) complexes.
    Choi S; Vastag L; Larrabee YC; Personick ML; Schaberg KB; Fowler BJ; Sandwick RK; Rawji G
    Inorg Chem; 2008 Feb; 47(4):1352-60. PubMed ID: 18220340
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oxidation of 3,6-dioxa-1,8-octanedithiol by platinum(IV) anticancer prodrug and model complex: kinetic and mechanistic studies.
    Huo S; Shen S; Liu D; Shi T
    J Phys Chem B; 2012 Jun; 116(22):6522-8. PubMed ID: 22574871
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antitumor Platinium(IV) Prodrugs: A Systematic Computational Exploration of Their Reduction Mechanism by l-Ascorbic Acid.
    Dabbish E; Ponte F; Russo N; Sicilia E
    Inorg Chem; 2019 Mar; 58(6):3851-3860. PubMed ID: 30843385
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A computational mechanistic investigation into the reduction of Pt(iv) prodrugs with two axial chlorides by biological reductants.
    Ejehi Z; Ariafard A
    Chem Commun (Camb); 2017 Jan; 53(8):1413-1416. PubMed ID: 28079213
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Influence of equatorial and axial carboxylato ligands on the kinetic inertness of platinum(IV) complexes in the presence of ascorbate and cysteine and within DLD-1 cancer cells.
    Chen CK; Zhang JZ; Aitken JB; Hambley TW
    J Med Chem; 2013 Nov; 56(21):8757-64. PubMed ID: 24107138
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kinetics and mechanism for reduction of the anticancer prodrug trans,trans,trans-[PtCl2(OH)2(c-C6H11NH2)(NH3)] (JM335) by thiols.
    Lemma K; Shi T; Elding LI
    Inorg Chem; 2000 Apr; 39(8):1728-34. PubMed ID: 12526561
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Facile preparation of mono-, di- and mixed-carboxylato platinum(IV) complexes for versatile anticancer prodrug design.
    Zhang JZ; Bonnitcha P; Wexselblatt E; Klein AV; Najajreh Y; Gibson D; Hambley TW
    Chemistry; 2013 Jan; 19(5):1672-6. PubMed ID: 23255183
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pt(IV) complexes as prodrugs for cisplatin.
    Shi Y; Liu SA; Kerwood DJ; Goodisman J; Dabrowiak JC
    J Inorg Biochem; 2012 Feb; 107(1):6-14. PubMed ID: 22169035
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of thioethers on DNA platination by trans-platinum complexes.
    Li C; Huang R; Ding Y; Sletten E; Arnesano F; Losacco M; Natile G; Liu Y
    Inorg Chem; 2011 Sep; 50(17):8168-76. PubMed ID: 21812429
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Platinum(IV) prodrugs with haloacetato ligands in the axial positions can undergo hydrolysis under biologically relevant conditions.
    Wexselblatt E; Yavin E; Gibson D
    Angew Chem Int Ed Engl; 2013 Jun; 52(23):6059-62. PubMed ID: 23686723
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modulation of oxidative DNA damage and DNA-crosslink formation induced by cis-diammine-tetrachloro-platinum(IV) in the presence of endogenous reductants.
    Nakai T; Ando M; Okamoto Y; Ueda K; Kojima N
    J Inorg Biochem; 2011 Jan; 105(1):1-5. PubMed ID: 21134595
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The preparation and characterization of trans-platinum(IV) complexes with unusually high cytotoxicity.
    Cubo L; Hambley TW; Sanz Miguel PJ; Carnero A; Navarro-Ranninger C; Quiroga AG
    Dalton Trans; 2011 Jan; 40(2):344-7. PubMed ID: 20936210
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New reduction pathways for ctc-[PtCl2(CH3CO2)2(NH3)(Am)] anticancer prodrugs.
    Nemirovski A; Vinograd I; Takrouri K; Mijovilovich A; Rompel A; Gibson D
    Chem Commun (Camb); 2010 Mar; 46(11):1842-4. PubMed ID: 20198227
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pt(IV) analogs of oxaliplatin that do not follow the expected correlation between electrochemical reduction potential and rate of reduction by ascorbate.
    Zhang JZ; Wexselblatt E; Hambley TW; Gibson D
    Chem Commun (Camb); 2012 Jan; 48(6):847-9. PubMed ID: 22124352
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanistic insight into protonolysis and cis-trans isomerization of benzylplatinum(II) complexes assisted by weak ligand-to-metal interactions. A combined kinetic and DFT study.
    Guido E; D'Amico G; Russo N; Sicilia E; Rizzato S; Albinati A; Romeo A; Plutino MR; Romeo R
    Inorg Chem; 2011 Mar; 50(6):2224-39. PubMed ID: 21341750
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oxidation of anticancer Pt(II) complexes with monodentate phosphane ligands: towards stable but active Pt(IV) prodrugs.
    Medrano MÁ; Álvarez-Valdés A; Perles J; Lloret-Fillol J; Muñoz-Galván S; Carnero A; Navarro-Ranninger C; Quiroga AG
    Chem Commun (Camb); 2013 May; 49(42):4806-8. PubMed ID: 23591566
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and X-ray crystal structure of trans,cis-[Pt(OAc)2I2(en)]: a novel type of cisplatin analog that can be photolyzed by visible light to DNA-binding and cytotoxic species in vitro.
    Kratochwil NA; Zabel M; Range KJ; Bednarski PJ
    J Med Chem; 1996 Jun; 39(13):2499-507. PubMed ID: 8691447
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cationic intermediates in oxidative addition reactions of Cl2 to [PtCl2(cis-1,4-DACH)].
    Margiotta N; Ranaldo R; Intini FP; Natile G
    Dalton Trans; 2011 Dec; 40(48):12877-85. PubMed ID: 22064914
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Studies on the photoactivation of two cytotoxic trans,trans,trans-diazidodiaminodihydroxo-Pt(IV) complexes.
    Westendorf AF; Bodtke A; Bednarski PJ
    Dalton Trans; 2011 May; 40(19):5342-51. PubMed ID: 21461431
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.