122 related articles for article (PubMed ID: 22921906)
1. The DNA topoisomerase II catalytic inhibitor merbarone is genotoxic and induces endoreduplication.
Pastor N; Domínguez I; Orta ML; Campanella C; Mateos S; Cortés F
Mutat Res; 2012; 738-739():45-51. PubMed ID: 22921906
[TBL] [Abstract][Full Text] [Related]
2. Differential cell cycle-specificity for chromosomal damage induced by merbarone and etoposide in V79 cells.
Wang L; Roy SK; Eastmond DA
Mutat Res; 2007 Mar; 616(1-2):70-82. PubMed ID: 17174356
[TBL] [Abstract][Full Text] [Related]
3. Characterization of novel human leukemic cell lines selected for resistance to merbarone, a catalytic inhibitor of DNA topoisomerase II.
Kusumoto H; Rodgers QE; Boege F; Raimondi SC; Beck WT
Cancer Res; 1996 Jun; 56(11):2573-83. PubMed ID: 8653700
[TBL] [Abstract][Full Text] [Related]
4. Catalytic inhibitors of topoisomerase II are DNA-damaging agents: induction of chromosomal damage by merbarone and ICRF-187.
Wang L; Eastmond DA
Environ Mol Mutagen; 2002; 39(4):348-56. PubMed ID: 12112387
[TBL] [Abstract][Full Text] [Related]
5. Differences in inhibition of chromosome separation and G2 arrest by DNA topoisomerase II inhibitors merbarone and VM-26.
Chen M; Beck WT
Cancer Res; 1995 Apr; 55(7):1509-16. PubMed ID: 7882360
[TBL] [Abstract][Full Text] [Related]
6. Merbarone, a catalytic inhibitor of DNA topoisomerase II, induces apoptosis in CEM cells through activation of ICE/CED-3-like protease.
Khélifa T; Beck WT
Mol Pharmacol; 1999 Mar; 55(3):548-56. PubMed ID: 10051540
[TBL] [Abstract][Full Text] [Related]
7. In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone.
Drake FH; Hofmann GA; Mong SM; Bartus JO; Hertzberg RP; Johnson RK; Mattern MR; Mirabelli CK
Cancer Res; 1989 May; 49(10):2578-83. PubMed ID: 2540903
[TBL] [Abstract][Full Text] [Related]
8. Evidence from studies with intact mammalian cells that merbarone and bis(dioxopiperazine)s are topoisomerase II poisons.
Snyder RD
Drug Chem Toxicol; 2003 Feb; 26(1):15-22. PubMed ID: 12643037
[TBL] [Abstract][Full Text] [Related]
9. Topoisomerase II inhibitors affect entry into mitosis and chromosome condensation in BHK cells.
Anderson H; Roberge M
Cell Growth Differ; 1996 Jan; 7(1):83-90. PubMed ID: 8788036
[TBL] [Abstract][Full Text] [Related]
10. Teniposide-resistant CEM cells, which express mutant DNA topoisomerase II alpha, when treated with non-complex-stabilizing inhibitors of the enzyme, display no cross-resistance and reveal aberrant functions of the mutant enzyme.
Chen M; Beck WT
Cancer Res; 1993 Dec; 53(24):5946-53. PubMed ID: 8261408
[TBL] [Abstract][Full Text] [Related]
11. Effects of DNA topoisomerase II inhibitors on human bone marrow progenitor cells.
Francis GE; Tejedor MC; Berney JJ; Chresta CM; Delgado C; Patel P
Leukemia; 1994 Jan; 8(1):121-8. PubMed ID: 8289477
[TBL] [Abstract][Full Text] [Related]
12. Interference with topoisomerase IIalpha potentiates melphalan cytotoxicity.
Hirota H; Gosky D; Berger NA; Chatterjee S
Int J Oncol; 2002 Feb; 20(2):311-8. PubMed ID: 11788894
[TBL] [Abstract][Full Text] [Related]
13. Induction of genotoxic and cytotoxic damage by aclarubicin, a dual topoisomerase inhibitor.
Hajji N; Mateos S; Pastor N; Domínguez I; Cortés F
Mutat Res; 2005 May; 583(1):26-35. PubMed ID: 15866463
[TBL] [Abstract][Full Text] [Related]
14. Toward a comprehensive model for induced endoreduplication.
Cortés F; Mateos S; Pastor N; Domínguez I
Life Sci; 2004 Nov; 76(2):121-35. PubMed ID: 15519359
[TBL] [Abstract][Full Text] [Related]
15. Application of fluorescence in situ hybridisation to study the relationship between cytotoxicity, chromosome aberrations, and changes in chromosome number after treatment with the topoisomerase II inhibitor amsacrine.
Ferguson LR; Whiteside G; Holdaway KM; Baguley BC
Environ Mol Mutagen; 1996; 27(4):255-62. PubMed ID: 8665870
[TBL] [Abstract][Full Text] [Related]
16. Tirapazamine: a hypoxia-activated topoisomerase II poison.
Peters KB; Brown JM
Cancer Res; 2002 Sep; 62(18):5248-53. PubMed ID: 12234992
[TBL] [Abstract][Full Text] [Related]
17. Human small cell lung cancer NYH cells selected for resistance to the bisdioxopiperazine topoisomerase II catalytic inhibitor ICRF-187 demonstrate a functional R162Q mutation in the Walker A consensus ATP binding domain of the alpha isoform.
Wessel I; Jensen LH; Jensen PB; Falck J; Rose A; Roerth M; Nitiss JL; Sehested M
Cancer Res; 1999 Jul; 59(14):3442-50. PubMed ID: 10416608
[TBL] [Abstract][Full Text] [Related]
18. The mycotoxin ochratoxin A inhibits DNA topoisomerase II and induces polyploidy in cultured CHO cells.
Cosimi S; Orta L; Mateos S; Cortés F
Toxicol In Vitro; 2009 Sep; 23(6):1110-5. PubMed ID: 19490938
[TBL] [Abstract][Full Text] [Related]
19. Topoisomerase II inhibition and high yield of endoreduplication induced by the flavonoids luteolin and quercetin.
Cantero G; Campanella C; Mateos S; Cortés F
Mutagenesis; 2006 Sep; 21(5):321-5. PubMed ID: 16950806
[TBL] [Abstract][Full Text] [Related]
20. Oncofetal HMGA2 attenuates genotoxic damage induced by topoisomerase II target compounds through the regulation of local DNA topology.
Ahmed SM; Dröge P
Mol Oncol; 2019 Oct; 13(10):2062-2078. PubMed ID: 31271486
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
