BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 22922311)

  • 1. A series of hybrid P450 BM3 enzymes with different catalytic activity in the light-initiated hydroxylation of lauric acid.
    Tran NH; Huynh N; Chavez G; Nguyen A; Dwaraknath S; Nguyen TA; Nguyen M; Cheruzel L
    J Inorg Biochem; 2012 Oct; 115():50-6. PubMed ID: 22922311
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insights into an efficient light-driven hybrid P450 BM3 enzyme from crystallographic, spectroscopic and biochemical studies.
    Spradlin J; Lee D; Mahadevan S; Mahomed M; Tang L; Lam Q; Colbert A; Shafaat OS; Goodin D; Kloos M; Kato M; Cheruzel LE
    Biochim Biophys Acta; 2016 Dec; 1864(12):1732-1738. PubMed ID: 27639964
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Light-initiated hydroxylation of lauric acid using hybrid P450 BM3 enzymes.
    Tran NH; Huynh N; Bui T; Nguyen Y; Huynh P; Cooper ME; Cheruzel LE
    Chem Commun (Camb); 2011 Nov; 47(43):11936-8. PubMed ID: 21975564
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An efficient light-driven P450 BM3 biocatalyst.
    Tran NH; Nguyen D; Dwaraknath S; Mahadevan S; Chavez G; Nguyen A; Dao T; Mullen S; Nguyen TA; Cheruzel LE
    J Am Chem Soc; 2013 Oct; 135(39):14484-7. PubMed ID: 24040992
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.
    Girvan HM; Levy CW; Williams P; Fisher K; Cheesman MR; Rigby SE; Leys D; Munro AW
    Biochem J; 2010 Apr; 427(3):455-66. PubMed ID: 20180779
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Active site substitution A82W improves the regioselectivity of steroid hydroxylation by cytochrome P450 BM3 mutants as rationalized by spin relaxation nuclear magnetic resonance studies.
    Rea V; Kolkman AJ; Vottero E; Stronks EJ; Ampt KA; Honing M; Vermeulen NP; Wijmenga SS; Commandeur JN
    Biochemistry; 2012 Jan; 51(3):750-60. PubMed ID: 22208729
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Process intensification for cytochrome P450 BM3-catalyzed oxy-functionalization of dodecanoic acid.
    Buergler MB; Dennig A; Nidetzky B
    Biotechnol Bioeng; 2020 Aug; 117(8):2377-2388. PubMed ID: 32369187
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Correlating the para-Substituent Effects on Ru(II)-Polypyridine Photophysical Properties and on the Corresponding Hybrid P450 BM3 Enzymes Photocatalytic Activity.
    Shalan H; Colbert A; Nguyen TT; Kato M; Cheruzel L
    Inorg Chem; 2017 Jun; 56(11):6558-6564. PubMed ID: 28537742
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: implications for the mechanism of electron transfer in the P450 BM3 dimer.
    Girvan HM; Dunford AJ; Neeli R; Ekanem IS; Waltham TN; Joyce MG; Leys D; Curtis RA; Williams P; Fisher K; Voice MW; Munro AW
    Arch Biochem Biophys; 2011 Mar; 507(1):75-85. PubMed ID: 20868649
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altering the regioselectivity of the subterminal fatty acid hydroxylase P450 BM-3 towards gamma- and delta-positions.
    Dietrich M; Do TA; Schmid RD; Pleiss J; Urlacher VB
    J Biotechnol; 2009 Jan; 139(1):115-7. PubMed ID: 18984016
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insights into electron leakage in the reaction cycle of cytochrome P450 BM3 revealed by kinetic modeling and mutagenesis.
    Lim JB; Barker KA; Eller KA; Jiang L; Molina V; Saifee JF; Sikes HD
    Protein Sci; 2015 Nov; 24(11):1874-83. PubMed ID: 26311413
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase.
    Roitel O; Scrutton NS; Munro AW
    Biochemistry; 2003 Sep; 42(36):10809-21. PubMed ID: 12962506
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of protein plasticity in computational rationalization studies on regioselectivity in testosterone hydroxylation by cytochrome P450 BM3 mutants.
    de Beer SB; van Bergen LA; Keijzer K; Rea V; Venkataraman H; Guerra CF; Bickelhaupt FM; Vermeulen NP; Commandeur JN; Geerke DP
    Curr Drug Metab; 2012 Feb; 13(2):155-66. PubMed ID: 22208530
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium.
    Gustafsson MC; Roitel O; Marshall KR; Noble MA; Chapman SK; Pessegueiro A; Fulco AJ; Cheesman MR; von Wachenfeldt C; Munro AW
    Biochemistry; 2004 May; 43(18):5474-87. PubMed ID: 15122913
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
    Park SH; Kim DH; Kim D; Kim DH; Jung HC; Pan JG; Ahn T; Kim D; Yun CH
    Drug Metab Dispos; 2010 May; 38(5):732-9. PubMed ID: 20100815
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency.
    Huang WC; Westlake AC; Maréchal JD; Joyce MG; Moody PC; Roberts GC
    J Mol Biol; 2007 Oct; 373(3):633-51. PubMed ID: 17868686
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Combining substrate dynamics, binding statistics, and energy barriers to rationalize regioselective hydroxylation of octane and lauric acid by CYP102A1 and mutants.
    Feenstra KA; Starikov EB; Urlacher VB; Commandeur JN; Vermeulen NP
    Protein Sci; 2007 Mar; 16(3):420-31. PubMed ID: 17322527
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cross-linked cytochrome P450 BM3 aggregates promoted by Ru(II)-diimine complexes bearing aldehyde groups.
    Do MQ; Henry E; Kato M; Cheruzel L
    J Inorg Biochem; 2018 Sep; 186():130-134. PubMed ID: 29890400
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Key mutations alter the cytochrome P450 BM3 conformational landscape and remove inherent substrate bias.
    Butler CF; Peet C; Mason AE; Voice MW; Leys D; Munro AW
    J Biol Chem; 2013 Aug; 288(35):25387-25399. PubMed ID: 23828198
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of cytochrome P450 BM3 phenylalanine-87 and threonine-268 in binding organic hydroperoxides.
    Roberts AG; Katayama J; Kaspera R; Ledwitch KV; Le Trong I; Stenkamp RE; Thompson JA; Totah RA
    Biochim Biophys Acta; 2016 Apr; 1860(4):669-77. PubMed ID: 26723172
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.