BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 22922788)

  • 1. Inhibition of lung cancer cells growth, motility and induction of apoptosis by Klotho, a novel secreted Wnt antagonist, in a dose-dependent manner.
    Chen B; Ma X; Liu S; Zhao W; Wu J
    Cancer Biol Ther; 2012 Oct; 13(12):1221-8. PubMed ID: 22922788
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overexpression of Klotho suppresses liver cancer progression and induces cell apoptosis by negatively regulating wnt/β-catenin signaling pathway.
    Sun H; Gao Y; Lu K; Zhao G; Li X; Li Z; Chang H
    World J Surg Oncol; 2015 Oct; 13():307. PubMed ID: 26499380
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Klotho inhibits growth and promotes apoptosis in human lung cancer cell line A549.
    Chen B; Wang X; Zhao W; Wu J
    J Exp Clin Cancer Res; 2010 Jul; 29(1):99. PubMed ID: 20642846
    [TBL] [Abstract][Full Text] [Related]  

  • 4. KL1 internal repeat mediates klotho tumor suppressor activities and inhibits bFGF and IGF-I signaling in pancreatic cancer.
    Abramovitz L; Rubinek T; Ligumsky H; Bose S; Barshack I; Avivi C; Kaufman B; Wolf I
    Clin Cancer Res; 2011 Jul; 17(13):4254-66. PubMed ID: 21571866
    [TBL] [Abstract][Full Text] [Related]  

  • 5. α-Klotho released from HK-2 cells inhibits osteogenic differentiation of renal interstitial fibroblasts by inactivating the Wnt-β-catenin pathway.
    Zhu Z; Ruan S; Jiang Y; Huang F; Xia W; Chen J; Cui Y; He C; Zeng F; Li Y; Chen Z; Chen H
    Cell Mol Life Sci; 2021 Dec; 78(23):7831-7849. PubMed ID: 34724098
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rab8 GTPase regulates Klotho-mediated inhibition of cell growth and progression by directly modulating its surface expression in human non-small cell lung cancer.
    Chen B; Huang S; Pisanic Ii TR; Stark A; Tao Y; Cheng B; Li Y; Wei Y; Zhao W; Wang TH; Wu J
    EBioMedicine; 2019 Nov; 49():118-132. PubMed ID: 31707148
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of Klotho contributes to cartilage damage by derepression of canonical Wnt/β-catenin signaling in osteoarthritis mice.
    Gu Y; Ren K; Wang L; Yao Q
    Aging (Albany NY); 2019 Dec; 11(24):12793-12809. PubMed ID: 31895692
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Klotho/FGF23 axis mediates high phosphate-induced vascular calcification in vascular smooth muscle cells via Wnt7b/β-catenin pathway.
    Chen YX; Huang C; Duan ZB; Xu CY; Chen Y
    Kaohsiung J Med Sci; 2019 Jul; 35(7):393-400. PubMed ID: 31001900
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Klotho is a novel therapeutic target in peritoneal fibrosis via Wnt signaling inhibition.
    Kadoya H; Satoh M; Nishi Y; Kondo M; Wada Y; Sogawa Y; Kidokoro K; Nagasu H; Sasaki T; Kashihara N
    Nephrol Dial Transplant; 2020 May; 35(5):773-781. PubMed ID: 32221606
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathway.
    Shan BE; Wang MX; Li RQ
    Cancer Invest; 2009 Jul; 27(6):604-12. PubMed ID: 19440933
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Klotho, an anti-aging gene, acts as a tumor suppressor and inhibitor of IGF-1R signaling in diffuse large B cell lymphoma.
    Zhou X; Fang X; Jiang Y; Geng L; Li X; Li Y; Lu K; Li P; Lv X; Wang X
    J Hematol Oncol; 2017 Feb; 10(1):37. PubMed ID: 28153033
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma.
    Lee J; Jeong DJ; Kim J; Lee S; Park JH; Chang B; Jung SI; Yi L; Han Y; Yang Y; Kim KI; Lim JS; Yang I; Jeon S; Bae DH; Kim CJ; Lee MS
    Mol Cancer; 2010 May; 9():109. PubMed ID: 20482749
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular basis of Klotho: from gene to function in aging.
    Xu Y; Sun Z
    Endocr Rev; 2015 Apr; 36(2):174-93. PubMed ID: 25695404
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Augmented Wnt signaling in a mammalian model of accelerated aging.
    Liu H; Fergusson MM; Castilho RM; Liu J; Cao L; Chen J; Malide D; Rovira II; Schimel D; Kuo CJ; Gutkind JS; Hwang PM; Finkel T
    Science; 2007 Aug; 317(5839):803-6. PubMed ID: 17690294
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The interplay of Klotho with signaling pathway and microRNAs in cancers.
    Abolghasemi M; Yousefi T; Maniati M; Qujeq D
    J Cell Biochem; 2019 Sep; 120(9):14306-14317. PubMed ID: 31127658
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Decreased Level of Klotho Contributes to Drug Resistance in Lung Cancer Cells: Involving in Klotho-Mediated Cell Autophagy.
    Chen T; Ren H; Thakur A; Yang T; Li Y; Zhang S; Wang T; Chen M
    DNA Cell Biol; 2016 Dec; 35(12):751-757. PubMed ID: 27661766
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Peruvoside targets apoptosis and autophagy through MAPK Wnt/β-catenin and PI3K/AKT/mTOR signaling pathways in human cancers.
    Reddy D; Kumavath R; Tan TZ; Ampasala DR; Kumar AP
    Life Sci; 2020 Jan; 241():117147. PubMed ID: 31830480
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Secreted and Transmembrane αKlotho Isoforms Have Different Spatio-Temporal Profiles in the Brain during Aging and Alzheimer's Disease Progression.
    Massó A; Sánchez A; Gimenez-Llort L; Lizcano JM; Cañete M; García B; Torres-Lista V; Puig M; Bosch A; Chillon M
    PLoS One; 2015; 10(11):e0143623. PubMed ID: 26599613
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The suppressive effect of soluble Klotho on fibroblastic growth factor 23 synthesis in UMR-106 osteoblast-like cells.
    Ma L; Gao M; Wu L; Zhao X; Mao H; Xing C
    Cell Biol Int; 2018 Sep; 42(9):1270-1274. PubMed ID: 29851201
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of Wnt signaling activity for growth suppression induced by quercetin in 4T1 murine mammary cancer cells.
    Kim H; Seo EM; Sharma AR; Ganbold B; Park J; Sharma G; Kang YH; Song DK; Lee SS; Nam JS
    Int J Oncol; 2013 Oct; 43(4):1319-25. PubMed ID: 23900432
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.