BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 22925071)

  • 1. Subtilisin-like proprotein convertase paired basic amino acid-cleaving enzyme 4 is required for chondrogenic differentiation in ATDC5 cells.
    Yuasa K; Futamatsu G; Kawano T; Muroshita M; Kageyama Y; Taichi H; Ishikawa H; Nagahama M; Matsuda Y; Tsuji A
    FEBS J; 2012 Nov; 279(21):3997-4009. PubMed ID: 22925071
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7.
    Scamuffa N; Basak A; Lalou C; Wargnier A; Marcinkiewicz J; Siegfried G; Chrétien M; Calvo F; Seidah NG; Khatib AM
    Gut; 2008 Nov; 57(11):1573-82. PubMed ID: 18664504
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inactivation of proprotein convertase, PACE4, by alpha1-antitrypsin Portland (alpha1-PDX), a blocker of proteolytic activation of bone morphogenetic protein during embryogenesis: evidence that PACE4 is able to form an SDS-stable acyl intermediate with alpha1-PDX.
    Tsuji A; Hashimoto E; Ikoma T; Taniguchi T; Mori K; Nagahama M; Matsuda Y
    J Biochem; 1999 Sep; 126(3):591-603. PubMed ID: 10467177
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pro-protein convertases (PCs) other than PC6 are not tightly regulated for implantation in the human endometrium.
    Freyer C; Kilpatrick LM; Salamonsen LA; Nie G
    Reproduction; 2007 Jun; 133(6):1189-97. PubMed ID: 17636173
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The proprotein convertases furin and PACE4 play a significant role in tumor progression.
    Bassi DE; Mahloogi H; Klein-Szanto AJ
    Mol Carcinog; 2000 Jun; 28(2):63-9. PubMed ID: 10900462
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Engineering of alpha1-antitrypsin variants selective for subtilisin-like proprotein convertases PACE4 and PC6: importance of the P2' residue in stable complex formation of the serpin with proprotein convertase.
    Tsuji A; Kanie H; Makise H; Yuasa K; Nagahama M; Matsuda Y
    Protein Eng Des Sel; 2007 Apr; 20(4):163-70. PubMed ID: 17351018
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Highly regulated expression of subtilisin-like proprotein convertase PACE4 (SPC4) during dentinogenesis.
    Akamatsu T; Matsuda Y; Tsumura K; Tada J; Parvin MN; Wei W; Kanamori N; Hosoi K
    Biochem Biophys Res Commun; 2000 Jun; 272(2):410-5. PubMed ID: 10833428
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Engineering of α1-antitrypsin variants with improved specificity for the proprotein convertase furin using site-directed random mutagenesis.
    Hada K; Isshiki K; Matsuda S; Yuasa K; Tsuji A
    Protein Eng Des Sel; 2013 Feb; 26(2):123-31. PubMed ID: 23155057
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A proteomic approach reveals transient association of reticulocalbin-3, a novel member of the CREC family, with the precursor of subtilisin-like proprotein convertase, PACE4.
    Tsuji A; Kikuchi Y; Sato Y; Koide S; Yuasa K; Nagahama M; Matsuda Y
    Biochem J; 2006 May; 396(1):51-9. PubMed ID: 16433634
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins.
    Nakayama K
    Biochem J; 1997 Nov; 327 ( Pt 3)(Pt 3):625-35. PubMed ID: 9599222
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Subtilisin-like proprotein convertase PACE4 is required for skeletal muscle differentiation.
    Yuasa K; Masuda T; Yoshikawa C; Nagahama M; Matsuda Y; Tsuji A
    J Biochem; 2009 Sep; 146(3):407-15. PubMed ID: 19520771
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparative study of the binding pockets of mammalian proprotein convertases and its implications for the design of specific small molecule inhibitors.
    Tian S; Jianhua W
    Int J Biol Sci; 2010 Feb; 6(1):89-95. PubMed ID: 20151049
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7.
    Lissitzky JC; Luis J; Munzer JS; Benjannet S; Parat F; Chrétien M; Marvaldi J; Seidah NG
    Biochem J; 2000 Feb; 346 Pt 1(Pt 1):133-8. PubMed ID: 10657249
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.
    Seidah NG; Chrétien M; Day R
    Biochimie; 1994; 76(3-4):197-209. PubMed ID: 7819324
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of selectivity of alpha1-antitrypsin variant by mutagenesis in its reactive site loop against proprotein convertase. A crucial role of the P4 arginine in PACE4 inhibition.
    Tsuji A; Ikoma T; Hashimoto E; Matsuda Y
    Protein Eng; 2002 Feb; 15(2):123-30. PubMed ID: 11917148
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition and transcriptional silencing of a subtilisin-like proprotein convertase, PACE4/SPC4, reduces the branching morphogenesis of and AQP5 expression in rat embryonic submandibular gland.
    Akamatsu T; Azlina A; Purwanti N; Karabasil MR; Hasegawa T; Yao C; Hosoi K
    Dev Biol; 2009 Jan; 325(2):434-43. PubMed ID: 19013448
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Subtilisin-like proprotein convertases, PACE4 and PC8, as well as furin, are endogenous proalbumin convertases in HepG2 cells.
    Mori K; Imamaki A; Nagata K; Yonetomi Y; Kiyokage-Yoshimoto R; Martin TJ; Gillespie MT; Nagahama M; Tsuji A; Matsuda Y
    J Biochem; 1999 Mar; 125(3):627-33. PubMed ID: 10050053
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Subtilisin-like proprotein convertase PACE4 (SPC4) is a candidate processing enzyme of bone morphogenetic proteins during tooth formation.
    Akamatsu T; Matsuda Y; Tsumura K; Tada J; Parvin MN; Kanamori N; Hosoi K
    Dev Dyn; 1999 Dec; 216(4-5):481-8. PubMed ID: 10633867
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pro-protein convertase gene expression in human breast cancer.
    Cheng M; Watson PH; Paterson JA; Seidah N; Chrétien M; Shiu RP
    Int J Cancer; 1997 Jun; 71(6):966-71. PubMed ID: 9185698
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases.
    Van de Ven WJ; Roebroek AJ; Van Duijnhoven HL
    Crit Rev Oncog; 1993; 4(2):115-36. PubMed ID: 8420571
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.