BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

440 related articles for article (PubMed ID: 22925968)

  • 1. Progress in overcoming the chain association issue in bispecific heterodimeric IgG antibodies.
    Klein C; Sustmann C; Thomas M; Stubenrauch K; Croasdale R; Schanzer J; Brinkmann U; Kettenberger H; Regula JT; Schaefer W
    MAbs; 2012; 4(6):653-63. PubMed ID: 22925968
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The use of CrossMAb technology for the generation of bi- and multispecific antibodies.
    Klein C; Schaefer W; Regula JT
    MAbs; 2016; 8(6):1010-20. PubMed ID: 27285945
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bispecific antibody derivatives based on full-length IgG formats.
    Grote M; Haas AK; Klein C; Schaefer W; Brinkmann U
    Methods Mol Biol; 2012; 901():247-63. PubMed ID: 22723106
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Production of bispecific antibodies in "knobs-into-holes" using a cell-free expression system.
    Xu Y; Lee J; Tran C; Heibeck TH; Wang WD; Yang J; Stafford RL; Steiner AR; Sato AK; Hallam TJ; Yin G
    MAbs; 2015; 7(1):231-42. PubMed ID: 25427258
    [TBL] [Abstract][Full Text] [Related]  

  • 5. "BIClonals": Production of Bispecific Antibodies in IgG Format in Transiently Transfected Mammalian Cells.
    Litvak-Greenfeld D; Vaks L; Dror S; Nahary L; Benhar I
    Methods Mol Biol; 2019; 1904():431-454. PubMed ID: 30539485
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Engineering therapeutic bispecific antibodies using CrossMab technology.
    Klein C; Schaefer W; Regula JT; Dumontet C; Brinkmann U; Bacac M; Umaña P
    Methods; 2019 Feb; 154():21-31. PubMed ID: 30453028
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel glycoengineered bispecific antibody format for targeted inhibition of epidermal growth factor receptor (EGFR) and insulin-like growth factor receptor type I (IGF-1R) demonstrating unique molecular properties.
    Schanzer JM; Wartha K; Croasdale R; Moser S; Künkele KP; Ries C; Scheuer W; Duerr H; Pompiati S; Pollman J; Stracke J; Lau W; Ries S; Brinkmann U; Klein C; Umana P
    J Biol Chem; 2014 Jul; 289(27):18693-706. PubMed ID: 24841203
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Engineering bispecific antibodies with defined chain pairing.
    Krah S; Sellmann C; Rhiel L; Schröter C; Dickgiesser S; Beck J; Zielonka S; Toleikis L; Hock B; Kolmar H; Becker S
    N Biotechnol; 2017 Oct; 39(Pt B):167-173. PubMed ID: 28137467
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Generation of Bispecific Antibodies by Fc Heterodimerization and their Application.
    Chen Z; Wang L; Xu T; Wang Q; Kang L; Zhao Q
    Curr Pharm Biotechnol; 2016; 17(15):1324-1332. PubMed ID: 27758688
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A single mutation increases heavy-chain heterodimer assembly of bispecific antibodies by inducing structural disorder in one homodimer species.
    Stutz C; Blein S
    J Biol Chem; 2020 Jul; 295(28):9392-9408. PubMed ID: 32404368
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The eIg technology to generate Ig-like bispecific antibodies.
    Kühl L; Aschmoneit N; Kontermann RE; Seifert O
    MAbs; 2022; 14(1):2063043. PubMed ID: 35427197
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A bispecific IgG format containing four independent antigen binding sites.
    Ljungars A; Schiött T; Mattson U; Steppa J; Hambe B; Semmrich M; Ohlin M; Tornberg UC; Mattsson M
    Sci Rep; 2020 Jan; 10(1):1546. PubMed ID: 32005942
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies.
    Schaefer W; Regula JT; Bähner M; Schanzer J; Croasdale R; Dürr H; Gassner C; Georges G; Kettenberger H; Imhof-Jung S; Schwaiger M; Stubenrauch KG; Sustmann C; Thomas M; Scheuer W; Klein C
    Proc Natl Acad Sci U S A; 2011 Jul; 108(27):11187-92. PubMed ID: 21690412
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rearranging the domain order of a diabody-based IgG-like bispecific antibody enhances its antitumor activity and improves its degradation resistance and pharmacokinetics.
    Asano R; Shimomura I; Konno S; Ito A; Masakari Y; Orimo R; Taki S; Arai K; Ogata H; Okada M; Furumoto S; Onitsuka M; Omasa T; Hayashi H; Katayose Y; Unno M; Kudo T; Umetsu M; Kumagai I
    MAbs; 2014; 6(5):1243-54. PubMed ID: 25517309
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Generation of dual-variable-domain immunoglobulin molecules for dual-specific targeting.
    Gu J; Ghayur T
    Methods Enzymol; 2012; 502():25-41. PubMed ID: 22208980
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel efficient bispecific antibody format, combining a conventional antigen-binding fragment with a single domain antibody, avoids potential heavy-light chain mis-pairing.
    Huang S; Segués A; Hulsik DL; Zaiss DM; Sijts AJAM; van Duijnhoven SMJ; van Elsas A
    J Immunol Methods; 2020 Aug; 483():112811. PubMed ID: 32569598
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair.
    Strop P; Ho WH; Boustany LM; Abdiche YN; Lindquist KC; Farias SE; Rickert M; Appah CT; Pascua E; Radcliffe T; Sutton J; Chaparro-Riggers J; Chen W; Casas MG; Chin SM; Wong OK; Liu SH; Vergara G; Shelton D; Rajpal A; Pons J
    J Mol Biol; 2012 Jul; 420(3):204-19. PubMed ID: 22543237
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bispecific antibody derivatives with restricted binding functionalities that are activated by proteolytic processing.
    Metz S; Panke C; Haas AK; Schanzer J; Lau W; Croasdale R; Hoffmann E; Schneider B; Auer J; Gassner C; Bossenmaier B; Umana P; Sustmann C; Brinkmann U
    Protein Eng Des Sel; 2012 Oct; 25(10):571-80. PubMed ID: 22976197
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Heavy and light chain pairing of bivalent quadroma and knobs-into-holes antibodies analyzed by UHR-ESI-QTOF mass spectrometry.
    Schaefer W; Völger HR; Lorenz S; Imhof-Jung S; Regula JT; Klein C; Mølhøj M
    MAbs; 2016; 8(1):49-55. PubMed ID: 26496506
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of tetravalent IgG1 dual targeting IGF-1R-EGFR antibodies with potent tumor inhibition.
    Croasdale R; Wartha K; Schanzer JM; Kuenkele KP; Ries C; Mayer K; Gassner C; Wagner M; Dimoudis N; Herter S; Jaeger C; Ferrara C; Hoffmann E; Kling L; Lau W; Staack RF; Heinrich J; Scheuer W; Stracke J; Gerdes C; Brinkmann U; Umana P; Klein C
    Arch Biochem Biophys; 2012 Oct; 526(2):206-18. PubMed ID: 22464987
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.