224 related articles for article (PubMed ID: 22927245)
1. Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model.
Xu H; Menendez S; Schlegelberger B; Bae N; Aplan PD; Göhring G; Deblasio TR; Nimer SD
Blood; 2012 Oct; 120(15):3089-97. PubMed ID: 22927245
[TBL] [Abstract][Full Text] [Related]
2. SETD2 deficiency accelerates MDS-associated leukemogenesis via S100a9 in NHD13 mice and predicts poor prognosis in MDS.
Chen BY; Song J; Hu CL; Chen SB; Zhang Q; Xu CH; Wu JC; Hou D; Sun M; Zhang YL; Liu N; Yu PC; Liu P; Zong LJ; Zhang JY; Dai RF; Lan F; Huang QH; Zhang SJ; Nimer SD; Chen Z; Chen SJ; Sun XJ; Wang L
Blood; 2020 Jun; 135(25):2271-2285. PubMed ID: 32202636
[TBL] [Abstract][Full Text] [Related]
3. PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia.
Guirguis AA; Slape CI; Failla LM; Saw J; Tremblay CS; Powell DR; Rossello F; Wei A; Strasser A; Curtis DJ
Cell Death Differ; 2016 Jun; 23(6):1049-59. PubMed ID: 26742432
[TBL] [Abstract][Full Text] [Related]
4. Depletion of cytotoxic T-cells does not protect NUP98-HOXD13 mice from myelodysplastic syndrome but reveals a modest tumor immunosurveillance effect.
Gough SM; Chung YJ; Aplan PD
PLoS One; 2012; 7(5):e36876. PubMed ID: 22606303
[TBL] [Abstract][Full Text] [Related]
5. Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome.
Balderman SR; Li AJ; Hoffman CM; Frisch BJ; Goodman AN; LaMere MW; Georger MA; Evans AG; Liesveld JL; Becker MW; Calvi LM
Blood; 2016 Feb; 127(5):616-25. PubMed ID: 26637787
[TBL] [Abstract][Full Text] [Related]
6. NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia.
Lin YW; Slape C; Zhang Z; Aplan PD
Blood; 2005 Jul; 106(1):287-95. PubMed ID: 15755899
[TBL] [Abstract][Full Text] [Related]
7. NUP98-HOX translocations lead to myelodysplastic syndrome in mice and men.
Slape C; Lin YW; Hartung H; Zhang Z; Wolff L; Aplan PD
J Natl Cancer Inst Monogr; 2008; (39):64-8. PubMed ID: 18648006
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome.
Slape CI; Saw J; Jowett JB; Aplan PD; Strasser A; Jane SM; Curtis DJ
Blood; 2012 Sep; 120(12):2475-83. PubMed ID: 22855610
[TBL] [Abstract][Full Text] [Related]
9. Progressive genomic instability in the Nup98-HoxD13 model of MDS correlates with loss of the PIG-A gene product.
Byrne M; Bennett RL; Cheng X; May WS
Neoplasia; 2014 Aug; 16(8):627-33. PubMed ID: 25220590
[TBL] [Abstract][Full Text] [Related]
10. Brief report: Loss of p15Ink4b accelerates development of myeloid neoplasms in Nup98-HoxD13 transgenic mice.
Humeniuk R; Koller R; Bies J; Aplan P; Wolff L
Stem Cells; 2014 May; 32(5):1361-6. PubMed ID: 24449168
[TBL] [Abstract][Full Text] [Related]
11. Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl.
Slape C; Liu LY; Beachy S; Aplan PD
Blood; 2008 Sep; 112(5):2017-9. PubMed ID: 18566322
[TBL] [Abstract][Full Text] [Related]
12. Oxidative stress leads to increased mutation frequency in a murine model of myelodysplastic syndrome.
Chung YJ; Robert C; Gough SM; Rassool FV; Aplan PD
Leuk Res; 2014 Jan; 38(1):95-102. PubMed ID: 23958061
[TBL] [Abstract][Full Text] [Related]
13. Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1.
Pineault N; Buske C; Feuring-Buske M; Abramovich C; Rosten P; Hogge DE; Aplan PD; Humphries RK
Blood; 2003 Jun; 101(11):4529-38. PubMed ID: 12543865
[TBL] [Abstract][Full Text] [Related]
14. Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome.
Chung YJ; Khawaja G; Wolcott KM; Aplan PD
J Vis Exp; 2018 Oct; (140):. PubMed ID: 30346380
[TBL] [Abstract][Full Text] [Related]
15. Thymic precursor cells generate acute myeloid leukemia in NUP98-PHF23/NUP98-HOXD13 double transgenic mice.
Kundu S; Park ES; Chung YJ; Walker RL; Zhu YJ; Negi V; Meltzer PS; Aplan PD
Sci Rep; 2019 Nov; 9(1):17213. PubMed ID: 31748606
[TBL] [Abstract][Full Text] [Related]
16. Transplantation of a myelodysplastic syndrome by a long-term repopulating hematopoietic cell.
Chung YJ; Choi CW; Slape C; Fry T; Aplan PD
Proc Natl Acad Sci U S A; 2008 Sep; 105(37):14088-93. PubMed ID: 18768819
[TBL] [Abstract][Full Text] [Related]
17. Apoptosis, bcl-2 expression and p53 accumulation in myelodysplastic syndrome, myelodysplastic-syndrome-derived acute myelogenous leukemia and de novo acute myelogenous leukemia.
Kurotaki H; Tsushima Y; Nagai K; Yagihashi S
Acta Haematol; 2000; 102(3):115-23. PubMed ID: 10692673
[TBL] [Abstract][Full Text] [Related]
18. Mouse embryonic stem cells that express a NUP98-HOXD13 fusion protein are impaired in their ability to differentiate and can be complemented by BCR-ABL.
Slape C; Chung YJ; Soloway PD; Tessarollo L; Aplan PD
Leukemia; 2007 Jun; 21(6):1239-48. PubMed ID: 17377591
[TBL] [Abstract][Full Text] [Related]
19. Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation.
Slape C; Hartung H; Lin YW; Bies J; Wolff L; Aplan PD
Cancer Res; 2007 Jun; 67(11):5148-55. PubMed ID: 17545593
[TBL] [Abstract][Full Text] [Related]
20. Molecular bases of myelodysplastic syndromes: lessons from animal models.
Komeno Y; Kitaura J; Kitamura T
J Cell Physiol; 2009 Jun; 219(3):529-34. PubMed ID: 19259975
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
