302 related articles for article (PubMed ID: 22927642)
1. Glycogen synthase kinase 3 inhibition promotes lysosomal biogenesis and autophagic degradation of the amyloid-β precursor protein.
Parr C; Carzaniga R; Gentleman SM; Van Leuven F; Walter J; Sastre M
Mol Cell Biol; 2012 Nov; 32(21):4410-8. PubMed ID: 22927642
[TBL] [Abstract][Full Text] [Related]
2. Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis.
Xiao Q; Yan P; Ma X; Liu H; Perez R; Zhu A; Gonzales E; Tripoli DL; Czerniewski L; Ballabio A; Cirrito JR; Diwan A; Lee JM
J Neurosci; 2015 Sep; 35(35):12137-51. PubMed ID: 26338325
[TBL] [Abstract][Full Text] [Related]
3. TFEB-mediated Enhancement of the Autophagy-lysosomal Pathway Dually Modulates the Process of Amyloid β-Protein Generation in Neurons.
Yamamoto F; Taniguchi K; Mamada N; Tamaoka A; Kametani F; Lakshmana MK; Araki W
Neuroscience; 2019 Mar; 402():11-22. PubMed ID: 30677488
[TBL] [Abstract][Full Text] [Related]
4. A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models.
Song JX; Malampati S; Zeng Y; Durairajan SSK; Yang CB; Tong BC; Iyaswamy A; Shang WB; Sreenivasmurthy SG; Zhu Z; Cheung KH; Lu JH; Tang C; Xu N; Li M
Aging Cell; 2020 Feb; 19(2):e13069. PubMed ID: 31858697
[TBL] [Abstract][Full Text] [Related]
5. Glycogen synthase kinase-3 (GSK3) inhibition induces prosurvival autophagic signals in human pancreatic cancer cells.
Marchand B; Arsenault D; Raymond-Fleury A; Boisvert FM; Boucher MJ
J Biol Chem; 2015 Feb; 290(9):5592-605. PubMed ID: 25561726
[TBL] [Abstract][Full Text] [Related]
6. Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia.
Bao J; Zheng L; Zhang Q; Li X; Zhang X; Li Z; Bai X; Zhang Z; Huo W; Zhao X; Shang S; Wang Q; Zhang C; Ji J
Protein Cell; 2016 Jun; 7(6):417-33. PubMed ID: 27209302
[TBL] [Abstract][Full Text] [Related]
7. Intermittent hypoxia therapy ameliorates beta-amyloid pathology via TFEB-mediated autophagy in murine Alzheimer's disease.
Wang X; Xie Y; Chen G; Lu Y; Wang D; Zhu L
J Neuroinflammation; 2023 Oct; 20(1):240. PubMed ID: 37864249
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes.
Ly PT; Wu Y; Zou H; Wang R; Zhou W; Kinoshita A; Zhang M; Yang Y; Cai F; Woodgett J; Song W
J Clin Invest; 2013 Jan; 123(1):224-35. PubMed ID: 23202730
[TBL] [Abstract][Full Text] [Related]
9. Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB).
Zheng X; Lin W; Jiang Y; Lu K; Wei W; Huo Q; Cui S; Yang X; Li M; Xu N; Tang C; Song JX
Autophagy; 2021 Nov; 17(11):3833-3847. PubMed ID: 33622188
[TBL] [Abstract][Full Text] [Related]
10. Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis.
Xiao Q; Yan P; Ma X; Liu H; Perez R; Zhu A; Gonzales E; Burchett JM; Schuler DR; Cirrito JR; Diwan A; Lee JM
J Neurosci; 2014 Jul; 34(29):9607-20. PubMed ID: 25031402
[TBL] [Abstract][Full Text] [Related]
11. Gypenoside XVII Enhances Lysosome Biogenesis and Autophagy Flux and Accelerates Autophagic Clearance of Amyloid-β through TFEB Activation.
Meng X; Luo Y; Liang T; Wang M; Zhao J; Sun G; Sun X
J Alzheimers Dis; 2016 Apr; 52(3):1135-50. PubMed ID: 27060963
[TBL] [Abstract][Full Text] [Related]
12. The Transcription Factor EB Reduces the Intraneuronal Accumulation of the Beta-Secretase-Derived APP Fragment C99 in Cellular and Mouse Alzheimer’s Disease Models.
Bécot A; Pardossi-Piquard R; Bourgeois A; Duplan E; Xiao Q; Diwan A; Lee JM; Lauritzen I; Checler F
Cells; 2020 May; 9(5):. PubMed ID: 32408680
[No Abstract] [Full Text] [Related]
13. Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer's disease models.
Guan XJ; Deng ZQ; Liu J; Su CF; Tong BC; Zhu Z; Sreenivasmurthy SG; Kan YX; Lu KJ; Chu CP; Pi RB; Cheung KH; Iyaswamy A; Song JX; Li M
Acta Pharmacol Sin; 2024 May; 45(5):900-913. PubMed ID: 38225393
[TBL] [Abstract][Full Text] [Related]
14. MEK1/2 inhibition rescues neurodegeneration by TFEB-mediated activation of autophagic lysosomal function in a model of Alzheimer's Disease.
Chun YS; Kim MY; Lee SY; Kim MJ; Hong TJ; Jeon JK; Ganbat D; Kim HT; Kim SS; Kam TI; Han S
Mol Psychiatry; 2022 Nov; 27(11):4770-4780. PubMed ID: 35948663
[TBL] [Abstract][Full Text] [Related]
15. Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome.
Salminen A; Kaarniranta K; Kauppinen A; Ojala J; Haapasalo A; Soininen H; Hiltunen M
Prog Neurobiol; 2013; 106-107():33-54. PubMed ID: 23827971
[TBL] [Abstract][Full Text] [Related]
16. Cu(II) disrupts autophagy-mediated lysosomal degradation of oligomeric Aβ in microglia via mTOR-TFEB pathway.
Tan X; Guan H; Yang Y; Luo S; Hou L; Chen H; Li J
Toxicol Appl Pharmacol; 2020 Aug; 401():115090. PubMed ID: 32512069
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies.
Avrahami L; Farfara D; Shaham-Kol M; Vassar R; Frenkel D; Eldar-Finkelman H
J Biol Chem; 2013 Jan; 288(2):1295-306. PubMed ID: 23155049
[TBL] [Abstract][Full Text] [Related]
18. Activation of the Wnt/β-catenin pathway represses the transcription of the β-amyloid precursor protein cleaving enzyme (BACE1) via binding of T-cell factor-4 to BACE1 promoter.
Parr C; Mirzaei N; Christian M; Sastre M
FASEB J; 2015 Feb; 29(2):623-35. PubMed ID: 25384422
[TBL] [Abstract][Full Text] [Related]
19. TFEB in Alzheimer's disease: From molecular mechanisms to therapeutic implications.
Gu Z; Cao H; Zuo C; Huang Y; Miao J; Song Y; Yang Y; Zhu L; Wang F
Neurobiol Dis; 2022 Oct; 173():105855. PubMed ID: 36031168
[TBL] [Abstract][Full Text] [Related]
20. TFEB acetylation promotes lysosome biogenesis and ameliorates Alzheimer's disease-relevant phenotypes in mice.
Li T; Yin L; Kang X; Xue W; Wang N; Zhang J; Yuan P; Lin L; Li Y
J Biol Chem; 2022 Dec; 298(12):102649. PubMed ID: 36441024
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
