These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 22927971)

  • 1. Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.
    Preukschas M; Hagel C; Schulte A; Weber K; Lamszus K; Sievert H; Pällmann N; Bokemeyer C; Hauber J; Braig M; Balabanov S
    PLoS One; 2012; 7(8):e43468. PubMed ID: 22927971
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
    Schultz CR; Geerts D; Mooney M; El-Khawaja R; Koster J; Bachmann AS
    Biochem J; 2018 Jan; 475(2):531-545. PubMed ID: 29295892
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes.
    Park JH; Dias CA; Lee SB; Valentini SR; Sokabe M; Fraser CS; Park MH
    Protein Eng Des Sel; 2011 Mar; 24(3):301-9. PubMed ID: 21131325
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biological Relevance and Therapeutic Potential of the Hypusine Modification System.
    Pällmann N; Braig M; Sievert H; Preukschas M; Hermans-Borgmeyer I; Schweizer M; Nagel CH; Neumann M; Wild P; Haralambieva E; Hagel C; Bokemeyer C; Hauber J; Balabanov S
    J Biol Chem; 2015 Jul; 290(30):18343-60. PubMed ID: 26037925
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification.
    Wolff EC; Kang KR; Kim YS; Park MH
    Amino Acids; 2007 Aug; 33(2):341-50. PubMed ID: 17476569
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on the growth of tumorigenic cell lines in culture.
    Shi XP; Yin KC; Ahern J; Davis LJ; Stern AM; Waxman L
    Biochim Biophys Acta; 1996 Jan; 1310(1):119-26. PubMed ID: 9244184
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Marked elevation of hypusine formation activity on eukaryotic initiation factor 5A in v-HA-RAS transformed mouse NIH3T3 cells.
    Chen ZP; Chen KY
    Cancer Lett; 1997 May; 115(2):235-41. PubMed ID: 9149130
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dramatic attenuation of hypusine formation on eukaryotic initiation factor 5A during senescence of IMR-90 human diploid fibroblasts.
    Chen ZP; Chen KY
    J Cell Physiol; 1997 Mar; 170(3):248-54. PubMed ID: 9066781
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein-protein-interaction network organization of the hypusine modification system.
    Sievert H; Venz S; Platas-Barradas O; Dhople VM; Schaletzky M; Nagel CH; Braig M; Preukschas M; Pällmann N; Bokemeyer C; Brümmendorf TH; Pörtner R; Walther R; Duncan KE; Hauber J; Balabanov S
    Mol Cell Proteomics; 2012 Nov; 11(11):1289-305. PubMed ID: 22888148
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypusine Signaling Promotes Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.
    Lemay SE; Grobs Y; Romanet C; Martineau S; Salem M; Shimauchi T; Breuils-Bonnet S; Bourgeois A; Théberge C; Pelletier A; Potus F; Provencher S; Bonnet S; Boucherat O
    Am J Respir Crit Care Med; 2024 Jun; 209(11):1376-1391. PubMed ID: 38261723
    [No Abstract]   [Full Text] [Related]  

  • 11. Hypusine: its post-translational formation in eukaryotic initiation factor 5A and its potential role in cellular regulation.
    Park MH; Wolff EC; Folk JE
    Biofactors; 1993 May; 4(2):95-104. PubMed ID: 8347280
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro and in vivo silencing of plasmodial dhs and eIf-5a genes in a putative, non-canonical RNAi-related pathway.
    Schwentke A; Krepstakies M; Mueller AK; Hammerschmidt-Kamper C; Motaal BA; Bernhard T; Hauber J; Kaiser A
    BMC Microbiol; 2012 Jun; 12():107. PubMed ID: 22694849
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Isolation and characterization of senescence-induced cDNAs encoding deoxyhypusine synthase and eucaryotic translation initiation factor 5A from tomato.
    Wang TW; Lu L; Wang D; Thompson JE
    J Biol Chem; 2001 May; 276(20):17541-9. PubMed ID: 11278418
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on endothelial cell growth, differentiation and apoptosis.
    Lee Y; Kim HK; Park HE; Park MH; Joe YA
    Mol Cell Biochem; 2002 Aug; 237(1-2):69-76. PubMed ID: 12236588
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties.
    Kaiser A; Hammels I; Gottwald A; Nassar M; Zaghloul MS; Motaal BA; Hauber J; Hoerauf A
    Bioorg Med Chem; 2007 Sep; 15(18):6200-7. PubMed ID: 17591443
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The eukaryotic initiation factor 5A is involved in the regulation of proliferation and apoptosis induced by interferon-alpha and EGF in human cancer cells.
    Caraglia M; Marra M; Giuberti G; D'Alessandro AM; Baldi A; Tassone P; Venuta S; Tagliaferri P; Abbruzzese A
    J Biochem; 2003 Jun; 133(6):757-65. PubMed ID: 12869532
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Is hypusine essential for eukaryotic cell proliferation?
    Park MH; Wolff EC; Folk JE
    Trends Biochem Sci; 1993 Dec; 18(12):475-9. PubMed ID: 8108861
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).
    Park MH
    J Biochem; 2006 Feb; 139(2):161-9. PubMed ID: 16452303
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural features of the eIF-5A precursor required for posttranslational synthesis of deoxyhypusine.
    Joe YA; Park MH
    J Biol Chem; 1994 Oct; 269(41):25916-21. PubMed ID: 7929297
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of eukaryotic initiation factor 5A with the human immunodeficiency virus type 1 Rev response element RNA and U6 snRNA requires deoxyhypusine or hypusine modification.
    Liu YP; Nemeroff M; Yan YP; Chen KY
    Biol Signals; 1997; 6(3):166-74. PubMed ID: 9285100
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.