BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 22927971)

  • 1. Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.
    Preukschas M; Hagel C; Schulte A; Weber K; Lamszus K; Sievert H; Pällmann N; Bokemeyer C; Hauber J; Braig M; Balabanov S
    PLoS One; 2012; 7(8):e43468. PubMed ID: 22927971
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
    Schultz CR; Geerts D; Mooney M; El-Khawaja R; Koster J; Bachmann AS
    Biochem J; 2018 Jan; 475(2):531-545. PubMed ID: 29295892
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes.
    Park JH; Dias CA; Lee SB; Valentini SR; Sokabe M; Fraser CS; Park MH
    Protein Eng Des Sel; 2011 Mar; 24(3):301-9. PubMed ID: 21131325
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biological Relevance and Therapeutic Potential of the Hypusine Modification System.
    Pällmann N; Braig M; Sievert H; Preukschas M; Hermans-Borgmeyer I; Schweizer M; Nagel CH; Neumann M; Wild P; Haralambieva E; Hagel C; Bokemeyer C; Hauber J; Balabanov S
    J Biol Chem; 2015 Jul; 290(30):18343-60. PubMed ID: 26037925
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification.
    Wolff EC; Kang KR; Kim YS; Park MH
    Amino Acids; 2007 Aug; 33(2):341-50. PubMed ID: 17476569
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on the growth of tumorigenic cell lines in culture.
    Shi XP; Yin KC; Ahern J; Davis LJ; Stern AM; Waxman L
    Biochim Biophys Acta; 1996 Jan; 1310(1):119-26. PubMed ID: 9244184
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Marked elevation of hypusine formation activity on eukaryotic initiation factor 5A in v-HA-RAS transformed mouse NIH3T3 cells.
    Chen ZP; Chen KY
    Cancer Lett; 1997 May; 115(2):235-41. PubMed ID: 9149130
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dramatic attenuation of hypusine formation on eukaryotic initiation factor 5A during senescence of IMR-90 human diploid fibroblasts.
    Chen ZP; Chen KY
    J Cell Physiol; 1997 Mar; 170(3):248-54. PubMed ID: 9066781
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein-protein-interaction network organization of the hypusine modification system.
    Sievert H; Venz S; Platas-Barradas O; Dhople VM; Schaletzky M; Nagel CH; Braig M; Preukschas M; Pällmann N; Bokemeyer C; Brümmendorf TH; Pörtner R; Walther R; Duncan KE; Hauber J; Balabanov S
    Mol Cell Proteomics; 2012 Nov; 11(11):1289-305. PubMed ID: 22888148
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypusine: its post-translational formation in eukaryotic initiation factor 5A and its potential role in cellular regulation.
    Park MH; Wolff EC; Folk JE
    Biofactors; 1993 May; 4(2):95-104. PubMed ID: 8347280
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro and in vivo silencing of plasmodial dhs and eIf-5a genes in a putative, non-canonical RNAi-related pathway.
    Schwentke A; Krepstakies M; Mueller AK; Hammerschmidt-Kamper C; Motaal BA; Bernhard T; Hauber J; Kaiser A
    BMC Microbiol; 2012 Jun; 12():107. PubMed ID: 22694849
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isolation and characterization of senescence-induced cDNAs encoding deoxyhypusine synthase and eucaryotic translation initiation factor 5A from tomato.
    Wang TW; Lu L; Wang D; Thompson JE
    J Biol Chem; 2001 May; 276(20):17541-9. PubMed ID: 11278418
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on endothelial cell growth, differentiation and apoptosis.
    Lee Y; Kim HK; Park HE; Park MH; Joe YA
    Mol Cell Biochem; 2002 Aug; 237(1-2):69-76. PubMed ID: 12236588
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties.
    Kaiser A; Hammels I; Gottwald A; Nassar M; Zaghloul MS; Motaal BA; Hauber J; Hoerauf A
    Bioorg Med Chem; 2007 Sep; 15(18):6200-7. PubMed ID: 17591443
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The eukaryotic initiation factor 5A is involved in the regulation of proliferation and apoptosis induced by interferon-alpha and EGF in human cancer cells.
    Caraglia M; Marra M; Giuberti G; D'Alessandro AM; Baldi A; Tassone P; Venuta S; Tagliaferri P; Abbruzzese A
    J Biochem; 2003 Jun; 133(6):757-65. PubMed ID: 12869532
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Is hypusine essential for eukaryotic cell proliferation?
    Park MH; Wolff EC; Folk JE
    Trends Biochem Sci; 1993 Dec; 18(12):475-9. PubMed ID: 8108861
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).
    Park MH
    J Biochem; 2006 Feb; 139(2):161-9. PubMed ID: 16452303
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural features of the eIF-5A precursor required for posttranslational synthesis of deoxyhypusine.
    Joe YA; Park MH
    J Biol Chem; 1994 Oct; 269(41):25916-21. PubMed ID: 7929297
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interaction of eukaryotic initiation factor 5A with the human immunodeficiency virus type 1 Rev response element RNA and U6 snRNA requires deoxyhypusine or hypusine modification.
    Liu YP; Nemeroff M; Yan YP; Chen KY
    Biol Signals; 1997; 6(3):166-74. PubMed ID: 9285100
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A unique modification of the eukaryotic initiation factor 5A shows the presence of the complete hypusine pathway in Leishmania donovani.
    Chawla B; Kumar RR; Tyagi N; Subramanian G; Srinivasan N; Park MH; Madhubala R
    PLoS One; 2012; 7(3):e33138. PubMed ID: 22438895
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.