BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 22928733)

  • 1. Neutron diffraction of acetazolamide-bound human carbonic anhydrase II reveals atomic details of drug binding.
    Fisher SZ; Aggarwal M; Kovalevsky AY; Silverman DN; McKenna R
    J Am Chem Soc; 2012 Sep; 134(36):14726-9. PubMed ID: 22928733
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Visualizing drug binding interactions using microcrystal electron diffraction.
    Clabbers MTB; Fisher SZ; Coinçon M; Zou X; Xu H
    Commun Biol; 2020 Jul; 3(1):417. PubMed ID: 32737395
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neutron structure of human carbonic anhydrase II in complex with methazolamide: mapping the solvent and hydrogen-bonding patterns of an effective clinical drug.
    Aggarwal M; Kovalevsky AY; Velazquez H; Fisher SZ; Smith JC; McKenna R
    IUCrJ; 2016 Sep; 3(Pt 5):319-325. PubMed ID: 28461893
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design.
    Sippel KH; Robbins AH; Domsic J; Genis C; Agbandje-McKenna M; McKenna R
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2009 Oct; 65(Pt 10):992-5. PubMed ID: 19851004
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of cryoprotectants on the structure and thermostability of the human carbonic anhydrase II-acetazolamide complex.
    Aggarwal M; Boone CD; Kondeti B; Tu C; Silverman DN; McKenna R
    Acta Crystallogr D Biol Crystallogr; 2013 May; 69(Pt 5):860-5. PubMed ID: 23633596
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of incorporating a thiophene tail in the scaffold of acetazolamide on the inhibition of human carbonic anhydrase isoforms I, II, IX and XII.
    Biswas S; McKenna R; Supuran CT
    Bioorg Med Chem Lett; 2013 Oct; 23(20):5646-9. PubMed ID: 23993330
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neutron structure of human carbonic anhydrase II: implications for proton transfer.
    Fisher SZ; Kovalevsky AY; Domsic JF; Mustyakimov M; McKenna R; Silverman DN; Langan PA
    Biochemistry; 2010 Jan; 49(3):415-21. PubMed ID: 20025241
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enzymes for carbon sequestration: neutron crystallographic studies of carbonic anhydrase.
    Fisher SZ; Kovalevsky AY; Domsic J; Mustyakimov M; Silverman DN; McKenna R; Langan P
    Acta Crystallogr D Biol Crystallogr; 2010 Nov; 66(Pt 11):1178-83. PubMed ID: 21041933
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Preliminary joint neutron and X-ray crystallographic study of human carbonic anhydrase II.
    Fisher SZ; Kovalevsky AY; Domsic JF; Mustyakimov M; Silverman DN; McKenna R; Langan P
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2009 May; 65(Pt 5):495-8. PubMed ID: 19407386
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Improved molecular recognition of Carbonic Anhydrase IX by polypeptide conjugation to acetazolamide.
    Yang J; Koruza K; Fisher Z; Knecht W; Baltzer L
    Bioorg Med Chem; 2017 Oct; 25(20):5838-5848. PubMed ID: 28943245
    [TBL] [Abstract][Full Text] [Related]  

  • 11. "To Be or Not to Be" Protonated: Atomic Details of Human Carbonic Anhydrase-Clinical Drug Complexes by Neutron Crystallography and Simulation.
    Kovalevsky A; Aggarwal M; Velazquez H; Cuneo MJ; Blakeley MP; Weiss KL; Smith JC; Fisher SZ; McKenna R
    Structure; 2018 Mar; 26(3):383-390.e3. PubMed ID: 29429876
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Case Study on the Use of Binding Free Energies to Screen Inhibitors of Human Carbonic Anhydrase II.
    Khatua S; De Bhowmik T; Taraphder S
    Chemphyschem; 2023 May; 24(10):e202200770. PubMed ID: 36695108
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Refined structure of the acetazolamide complex of human carbonic anhydrase II at 1.9 A.
    Vidgren J; Liljas A; Walker NP
    Int J Biol Macromol; 1990 Dec; 12(6):342-4. PubMed ID: 2128470
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Production and X-ray crystallographic analysis of fully deuterated human carbonic anhydrase II.
    Budayova-Spano M; Fisher SZ; Dauvergne MT; Agbandje-McKenna M; Silverman DN; Myles DA; McKenna R
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2006 Jan; 62(Pt 1):6-9. PubMed ID: 16511248
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structure and kinetic studies of a tetrameric type II β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.
    Ferraroni M; Del Prete S; Vullo D; Capasso C; Supuran CT
    Acta Crystallogr D Biol Crystallogr; 2015 Dec; 71(Pt 12):2449-56. PubMed ID: 26627652
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII.
    Ibrahim DA; Lasheen DS; Zaky MY; Ibrahim AW; Vullo D; Ceruso M; Supuran CT; Abou El Ella DA
    Bioorg Med Chem; 2015 Aug; 23(15):4989-4999. PubMed ID: 26048024
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neutron structure of human carbonic anhydrase II: a hydrogen-bonded water network "switch" is observed between pH 7.8 and 10.0.
    Fisher Z; Kovalevsky AY; Mustyakimov M; Silverman DN; McKenna R; Langan P
    Biochemistry; 2011 Nov; 50(44):9421-3. PubMed ID: 21988105
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural studies of β-carbonic anhydrase from the green alga Coccomyxa: inhibitor complexes with anions and acetazolamide.
    Huang S; Hainzl T; Grundström C; Forsman C; Samuelsson G; Sauer-Eriksson AE
    PLoS One; 2011; 6(12):e28458. PubMed ID: 22162771
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
    Pinard MA; Boone CD; Rife BD; Supuran CT; McKenna R
    Bioorg Med Chem; 2013 Nov; 21(22):7210-5. PubMed ID: 24090602
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors.
    Abdel-Aziz AA; El-Azab AS; Ekinci D; Şentürk M; Supuran CT
    J Enzyme Inhib Med Chem; 2015 Feb; 30(1):81-4. PubMed ID: 24666299
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.