392 related articles for article (PubMed ID: 22932900)
1. Activation of peroxisome proliferator-activated receptor α (PPARα) suppresses hypoxia-inducible factor-1α (HIF-1α) signaling in cancer cells.
Zhou J; Zhang S; Xue J; Avery J; Wu J; Lind SE; Ding WQ
J Biol Chem; 2012 Oct; 287(42):35161-35169. PubMed ID: 22932900
[TBL] [Abstract][Full Text] [Related]
2. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
Carroll VA; Ashcroft M
Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
[TBL] [Abstract][Full Text] [Related]
3. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
Blancher C; Moore JW; Robertson N; Harris AL
Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
[TBL] [Abstract][Full Text] [Related]
4. Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.
Chintala S; Najrana T; Toth K; Cao S; Durrani FA; Pili R; Rustum YM
BMC Cancer; 2012 Jul; 12():293. PubMed ID: 22804960
[TBL] [Abstract][Full Text] [Related]
5. HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs).
De Francesco EM; Lappano R; Santolla MF; Marsico S; Caruso A; Maggiolini M
Breast Cancer Res; 2013; 15(4):R64. PubMed ID: 23947803
[TBL] [Abstract][Full Text] [Related]
6. Antiangiogenic activity of phthalides-enriched Angelica Sinensis extract by suppressing WSB-1/pVHL/HIF-1α/VEGF signaling in bladder cancer.
Chen MC; Hsu WL; Chang WL; Chou TC
Sci Rep; 2017 Jul; 7(1):5376. PubMed ID: 28710377
[TBL] [Abstract][Full Text] [Related]
7. Rhapontigenin inhibited hypoxia inducible factor 1 alpha accumulation and angiogenesis in hypoxic PC-3 prostate cancer cells.
Jung DB; Lee HJ; Jeong SJ; Lee HJ; Lee EO; Kim YC; Ahn KS; Chen CY; Kim SH
Biol Pharm Bull; 2011; 34(6):850-5. PubMed ID: 21628883
[TBL] [Abstract][Full Text] [Related]
8. Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions.
Jung YS; Lee SJ; Yoon MH; Ha NC; Park BJ
Cell Cycle; 2012 Dec; 11(23):4462-73. PubMed ID: 23159849
[TBL] [Abstract][Full Text] [Related]
9. trans-3,4,5'-Trihydroxystibene inhibits hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in human ovarian cancer cells.
Cao Z; Fang J; Xia C; Shi X; Jiang BH
Clin Cancer Res; 2004 Aug; 10(15):5253-63. PubMed ID: 15297429
[TBL] [Abstract][Full Text] [Related]
10. Activation of hypoxia-induced transcription in normoxia.
Hägg M; Wennström S
Exp Cell Res; 2005 May; 306(1):180-91. PubMed ID: 15878343
[TBL] [Abstract][Full Text] [Related]
11. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.
Osada R; Horiuchi A; Kikuchi N; Yoshida J; Hayashi A; Ota M; Katsuyama Y; Melillo G; Konishi I
Hum Pathol; 2007 Sep; 38(9):1310-20. PubMed ID: 17555795
[TBL] [Abstract][Full Text] [Related]
12. PPARα regulates mobilization and homing of endothelial progenitor cells through the HIF-1α/SDF-1 pathway.
Wang Z; Moran E; Ding L; Cheng R; Xu X; Ma JX
Invest Ophthalmol Vis Sci; 2014 May; 55(6):3820-32. PubMed ID: 24845641
[TBL] [Abstract][Full Text] [Related]
13. Runx2 protein stabilizes hypoxia-inducible factor-1α through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes.
Lee SH; Che X; Jeong JH; Choi JY; Lee YJ; Lee YH; Bae SC; Lee YM
J Biol Chem; 2012 Apr; 287(18):14760-71. PubMed ID: 22351759
[TBL] [Abstract][Full Text] [Related]
14. GPER mediates the angiocrine actions induced by IGF1 through the HIF-1α/VEGF pathway in the breast tumor microenvironment.
De Francesco EM; Sims AH; Maggiolini M; Sotgia F; Lisanti MP; Clarke RB
Breast Cancer Res; 2017 Dec; 19(1):129. PubMed ID: 29212519
[TBL] [Abstract][Full Text] [Related]
15. Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein.
Song X; Yao J; Wang F; Zhou M; Zhou Y; Wang H; Wei L; Zhao L; Li Z; Lu N; Guo Q
Toxicol Appl Pharmacol; 2013 Sep; 271(2):144-55. PubMed ID: 23707765
[TBL] [Abstract][Full Text] [Related]
16. COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1alpha via HSP90/70.
van de Sluis B; Groot AJ; Vermeulen J; van der Wall E; van Diest PJ; Wijmenga C; Klomp LW; Vooijs M
PLoS One; 2009 Oct; 4(10):e7332. PubMed ID: 19802386
[TBL] [Abstract][Full Text] [Related]
17. Apolipoprotein A-I mimetic peptides inhibit expression and activity of hypoxia-inducible factor-1α in human ovarian cancer cell lines and a mouse ovarian cancer model.
Gao F; Chattopadhyay A; Navab M; Grijalva V; Su F; Fogelman AM; Reddy ST; Farias-Eisner R
J Pharmacol Exp Ther; 2012 Aug; 342(2):255-62. PubMed ID: 22537771
[TBL] [Abstract][Full Text] [Related]
18. Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron.
Park SS; Bae I; Lee YJ
J Cell Biochem; 2008 Apr; 103(6):1989-98. PubMed ID: 17973296
[TBL] [Abstract][Full Text] [Related]
19. Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha.
André H; Pereira TS
J Biol Chem; 2008 Oct; 283(43):29375-84. PubMed ID: 18694926
[TBL] [Abstract][Full Text] [Related]
20. iASPP is essential for HIF-1α stabilization to promote angiogenesis and glycolysis via attenuating VHL-mediated protein degradation.
Zhao D; Zheng S; Wang X; Liu H; Zhao K; Li L; Hu Y
Oncogene; 2022 Mar; 41(13):1944-1958. PubMed ID: 35169254
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
