85 related articles for article (PubMed ID: 22933344)
1. Identification of CYP isozymes involved in benzbromarone metabolism in human liver microsomes.
Kobayashi K; Kajiwara E; Ishikawa M; Oka H; Chiba K
Biopharm Drug Dispos; 2012 Nov; 33(8):466-73. PubMed ID: 22933344
[TBL] [Abstract][Full Text] [Related]
2. Identification of novel glutathione adducts of benzbromarone in human liver microsomes.
Cho N; Kobayashi K; Yoshida M; Kogure N; Takayama H; Chiba K
Drug Metab Pharmacokinet; 2017 Feb; 32(1):46-52. PubMed ID: 28131653
[TBL] [Abstract][Full Text] [Related]
3. Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450.
Zhao XJ; Yokoyama H; Chiba K; Wanwimolruk S; Ishizaki T
J Pharmacol Exp Ther; 1996 Dec; 279(3):1327-34. PubMed ID: 8968357
[TBL] [Abstract][Full Text] [Related]
4. Sequential metabolism and bioactivation of the hepatotoxin benzbromarone: formation of glutathione adducts from a catechol intermediate.
McDonald MG; Rettie AE
Chem Res Toxicol; 2007 Dec; 20(12):1833-42. PubMed ID: 18020424
[TBL] [Abstract][Full Text] [Related]
5. Characterization of the cytochrome P450 enzymes involved in the metabolism of a new cardioprotective agent KR-33028.
Kim H; Yoon YJ; Kim H; Kang S; Cheon HG; Yoo SE; Shin JG; Liu KH
Toxicol Lett; 2006 Oct; 166(2):105-14. PubMed ID: 16857327
[TBL] [Abstract][Full Text] [Related]
6. Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist.
Ghosal A; Lu X; Penner N; Gao L; Ramanathan R; Chowdhury SK; Kishnani NS; Alton KB
Drug Metab Dispos; 2011 Jan; 39(1):30-8. PubMed ID: 20926621
[TBL] [Abstract][Full Text] [Related]
7. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
Miyazawa M; Shindo M; Shimada T
Drug Metab Dispos; 2001 Feb; 29(2):200-5. PubMed ID: 11159812
[TBL] [Abstract][Full Text] [Related]
8. [O-methyl 14C]naproxen O-demethylase activity in human liver microsomes: evidence for the involvement of cytochrome P4501A2 and P4502C9/10.
Rodrigues AD; Kukulka MJ; Roberts EM; Ouellet D; Rodgers TR
Drug Metab Dispos; 1996 Jan; 24(1):126-36. PubMed ID: 8825200
[TBL] [Abstract][Full Text] [Related]
9. Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: roles of cytochromes P450 2C9, 2C19, and 3A4.
Komatsu T; Yamazaki H; Asahi S; Gillam EM; Guengerich FP; Nakajima M; Yokoi T
Drug Metab Dispos; 2000 Nov; 28(11):1361-8. PubMed ID: 11038165
[TBL] [Abstract][Full Text] [Related]
10. Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.
Huskey SW; Dean DC; Miller RR; Rasmusson GH; Chiu SH
Drug Metab Dispos; 1995 Oct; 23(10):1126-35. PubMed ID: 8654202
[TBL] [Abstract][Full Text] [Related]
11. Characterization of hepatic drug-metabolizing activities of Bama miniature pigs (Sus scrofa domestica): comparison with human enzyme analogs.
Li J; Liu Y; Zhang JW; Wei H; Yang L
Comp Med; 2006 Aug; 56(4):286-90. PubMed ID: 16941956
[TBL] [Abstract][Full Text] [Related]
12. Prediction of human liver microsomal oxidations of 7-ethoxycoumarin and chlorzoxazone with kinetic parameters of recombinant cytochrome P-450 enzymes.
Shimada T; Tsumura F; Yamazaki H
Drug Metab Dispos; 1999 Nov; 27(11):1274-80. PubMed ID: 10534312
[TBL] [Abstract][Full Text] [Related]
13. Identification of human cytochrome P-450 isoforms involved in metabolism of R(+)- and S(-)-gallopamil: utility of in vitro disappearance rate.
Suzuki A; Iida I; Tanaka F; Akimoto M; Fukushima K; Tani M; Ishizaki T; Chiba K
Drug Metab Dispos; 1999 Nov; 27(11):1254-9. PubMed ID: 10534309
[TBL] [Abstract][Full Text] [Related]
14. Identification of the human liver cytochrome P450 enzymes involved in the metabolism of zileuton (ABT-077) and its N-dehydroxylated metabolite, Abbott-66193.
Machinist JM; Mayer MD; Shet MS; Ferrero JL; Rodrigues AD
Drug Metab Dispos; 1995 Oct; 23(10):1163-74. PubMed ID: 8654206
[TBL] [Abstract][Full Text] [Related]
15. Studies on the cytochrome P450 (CYP)-mediated metabolic properties of miocamycin: evaluation of the possibility of a metabolic intermediate complex formation with CYP, and identification of the human CYP isoforms.
Kasahara M; Suzuki H; Komiya I
Drug Metab Dispos; 2000 Apr; 28(4):409-17. PubMed ID: 10725309
[TBL] [Abstract][Full Text] [Related]
16. Identification of Epoxide-Derived Metabolite(s) of Benzbromarone.
Wang K; Wang H; Peng Y; Zheng J
Drug Metab Dispos; 2016 Apr; 44(4):607-15. PubMed ID: 26792818
[TBL] [Abstract][Full Text] [Related]
17. A study on the metabolism of etoposide and possible interactions with antitumor or supporting agents by human liver microsomes.
Kawashiro T; Yamashita K; Zhao XJ; Koyama E; Tani M; Chiba K; Ishizaki T
J Pharmacol Exp Ther; 1998 Sep; 286(3):1294-300. PubMed ID: 9732391
[TBL] [Abstract][Full Text] [Related]
18. Cytotoxic effects of benzbromarone and its 1'-hydroxy metabolite in human hepatocarcinoma FLC4 cells cultured on micro-space cell culture plates.
Kobayashi K; Kajiwara E; Ishikawa M; Mimura H; Oka H; Ejiri Y; Hosoda M; Chiba K
Drug Metab Pharmacokinet; 2013; 28(3):265-8. PubMed ID: 23229783
[TBL] [Abstract][Full Text] [Related]
19. Identification of the human liver cytochrome P450 isoenzyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid.
Zhou S; Paxton JW; Tingle MD; Kestell P
Drug Metab Dispos; 2000 Dec; 28(12):1449-56. PubMed ID: 11095582
[TBL] [Abstract][Full Text] [Related]
20. The inhibitory effect of tannic acid on cytochrome P450 enzymes and NADPH-CYP reductase in rat and human liver microsomes.
Yao HT; Chang YW; Lan SJ; Yeh TK
Food Chem Toxicol; 2008 Feb; 46(2):645-53. PubMed ID: 17950511
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
