225 related articles for article (PubMed ID: 22934984)
21. ROCK inhibitors 3: Design, synthesis and structure-activity relationships of 7-azaindole-based Rho kinase (ROCK) inhibitors.
Bandarage UK; Cao J; Come JH; Court JJ; Gao H; Jacobs MD; Marhefka C; Nanthakumar S; Green J
Bioorg Med Chem Lett; 2018 Aug; 28(15):2622-2626. PubMed ID: 30082069
[TBL] [Abstract][Full Text] [Related]
22. Discovery of Rho-kinase inhibitors by docking-based virtual screening.
Shen M; Yu H; Li Y; Li P; Pan P; Zhou S; Zhang L; Li S; Lee SM; Hou T
Mol Biosyst; 2013 Jun; 9(6):1511-21. PubMed ID: 23549429
[TBL] [Abstract][Full Text] [Related]
23. Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.
Ray P; Wright J; Adam J; Bennett J; Boucharens S; Black D; Cook A; Brown AR; Epemolu O; Fletcher D; Haunso A; Huggett M; Jones P; Laats S; Lyons A; Mestres J; de Man J; Morphy R; Rankovic Z; Sherborne B; Sherry L; van Straten N; Westwood P; Zaman GZ
Bioorg Med Chem Lett; 2011 Jan; 21(1):97-101. PubMed ID: 21145740
[TBL] [Abstract][Full Text] [Related]
24. High-throughput virtual screening using quantum mechanical probes: discovery of selective kinase inhibitors.
Zhou T; Caflisch A
ChemMedChem; 2010 Jul; 5(7):1007-14. PubMed ID: 20540063
[TBL] [Abstract][Full Text] [Related]
25. Discovery of novel TAOK2 inhibitor scaffolds from high-throughput screening.
Piala AT; Akella R; Potts MB; Dudics-Giagnocavo SA; He H; Wei S; White MA; Posner BA; Goldsmith EJ
Bioorg Med Chem Lett; 2016 Aug; 26(16):3923-7. PubMed ID: 27426302
[TBL] [Abstract][Full Text] [Related]
26. A High-Throughput Radiometric Kinase Assay.
Duong-Ly KC; Peterson JR
Methods Mol Biol; 2016; 1360():87-95. PubMed ID: 26501904
[TBL] [Abstract][Full Text] [Related]
27. Design, Synthesis, and Structure-Activity Relationships of Pyridine-Based Rho Kinase (ROCK) Inhibitors.
Green J; Cao J; Bandarage UK; Gao H; Court J; Marhefka C; Jacobs M; Taslimi P; Newsome D; Nakayama T; Shah S; Rodems S
J Med Chem; 2015 Jun; 58(12):5028-37. PubMed ID: 26039570
[TBL] [Abstract][Full Text] [Related]
28. Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors.
Feng Y; Yin Y; Weiser A; Griffin E; Cameron MD; Lin L; Ruiz C; Schürer SC; Inoue T; Rao PV; Schröter T; Lograsso P
J Med Chem; 2008 Nov; 51(21):6642-5. PubMed ID: 18834107
[TBL] [Abstract][Full Text] [Related]
29. Cardiovascular effects of a novel potent and highly selective azaindole-based inhibitor of Rho-kinase.
Kast R; Schirok H; Figueroa-Pérez S; Mittendorf J; Gnoth MJ; Apeler H; Lenz J; Franz JK; Knorr A; Hütter J; Lobell M; Zimmermann K; Münter K; Augstein KH; Ehmke H; Stasch JP
Br J Pharmacol; 2007 Dec; 152(7):1070-80. PubMed ID: 17934515
[TBL] [Abstract][Full Text] [Related]
30. Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics.
Zhang W; Hu X; Chakravarty H; Yang Z; Tam KY
ACS Comb Sci; 2018 Nov; 20(11):660-671. PubMed ID: 30350563
[TBL] [Abstract][Full Text] [Related]
31. Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds.
Gong GQ; Wang K; Dai XC; Zhou Y; Basnet R; Chen Y; Yang DH; Lee WJ; Buchanan CM; Flanagan JU; Shepherd PR; Chen Y; Wang MW
Acta Pharmacol Sin; 2018 Dec; 39(12):1902-1912. PubMed ID: 30038340
[TBL] [Abstract][Full Text] [Related]
32. Ligand efficiency based approach for efficient virtual screening of compound libraries.
Ke YY; Coumar MS; Shiao HY; Wang WC; Chen CW; Song JS; Chen CH; Lin WH; Wu SH; Hsu JT; Chang CM; Hsieh HP
Eur J Med Chem; 2014 Aug; 83():226-35. PubMed ID: 24960626
[TBL] [Abstract][Full Text] [Related]
33. Design, synthesis, and biological evaluation of urea-based ROCK2 inhibitors.
Wang L; Qi J; Fan M; Yao L
Chem Biol Drug Des; 2021 Dec; 98(6):969-978. PubMed ID: 34581498
[TBL] [Abstract][Full Text] [Related]
34. ROCK inhibitors 4: Structure-activity relationship studies of 7-azaindole-based rho kinase (ROCK) inhibitors.
Bandarage UK; Court J; Gao H; Nanthakumar S; Come JH; Giroux S; Green J
Bioorg Med Chem Lett; 2021 Feb; 33():127721. PubMed ID: 33259926
[TBL] [Abstract][Full Text] [Related]
35. Determination of Affinity and Residence Time of Potent Drug-Target Complexes by Label-free Biosensing.
Quinn JG; Pitts KE; Steffek M; Mulvihill MM
J Med Chem; 2018 Jun; 61(12):5154-5161. PubMed ID: 29772180
[TBL] [Abstract][Full Text] [Related]
36. The design, annotation, and application of a kinase-targeted library.
Xi H; Lunney EA
Methods Mol Biol; 2011; 685():279-91. PubMed ID: 20981529
[TBL] [Abstract][Full Text] [Related]
37. Kinase inhibitor data modeling and de novo inhibitor design with fragment approaches.
Vieth M; Erickson J; Wang J; Webster Y; Mader M; Higgs R; Watson I
J Med Chem; 2009 Oct; 52(20):6456-66. PubMed ID: 19791746
[TBL] [Abstract][Full Text] [Related]
38. Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity.
Sharlow ER; Mustata Wilson G; Close D; Leimgruber S; Tandon M; Reed RB; Shun TY; Wang QJ; Wipf P; Lazo JS
PLoS One; 2011; 6(10):e25134. PubMed ID: 21998636
[TBL] [Abstract][Full Text] [Related]
39. A time-resolved fluorescence resonance energy transfer assay for high-throughput screening of 14-3-3 protein-protein interaction inhibitors.
Du Y; Fu RW; Lou B; Zhao J; Qui M; Khuri FR; Fu H
Assay Drug Dev Technol; 2013 Jul; 11(6):367-81. PubMed ID: 23906346
[TBL] [Abstract][Full Text] [Related]
40. TR-FRET-based high-throughput screening assay for identification of UBC13 inhibitors.
Madiraju C; Welsh K; Cuddy MP; Godoi PH; Pass I; Ngo T; Vasile S; Sergienko EA; Diaz P; Matsuzawa S; Reed JC
J Biomol Screen; 2012 Feb; 17(2):163-76. PubMed ID: 22034497
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
