These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 22941475)

  • 21. GDC-0449--targeting the hedgehog signaling pathway.
    Dierks C
    Recent Results Cancer Res; 2010; 184():235-8. PubMed ID: 20072843
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Recent advances in the design of Hedgehog pathway inhibitors for the treatment of malignancies.
    Banerjee U; Hadden MK
    Expert Opin Drug Discov; 2014 Jul; 9(7):751-71. PubMed ID: 24850423
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mechanisms of Hedgehog signalling in cancer.
    Marini KD; Payne BJ; Watkins DN; Martelotto LG
    Growth Factors; 2011 Dec; 29(6):221-34. PubMed ID: 21875383
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Blocking smoothened cholesterylation: A strategy for overcoming drug resistance in cancer.
    Cheng SY; Zhang YE
    Cell Chem Biol; 2024 Jul; 31(7):1231-1233. PubMed ID: 39029450
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Small molecule antagonists in distinct binding modes inhibit drug-resistant mutant of smoothened.
    Tao H; Jin Q; Koo DI; Liao X; Englund NP; Wang Y; Ramamurthy A; Schultz PG; Dorsch M; Kelleher J; Wu X
    Chem Biol; 2011 Apr; 18(4):432-7. PubMed ID: 21513879
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Hedgehog signaling pathway: development of antagonists for cancer therapy.
    Xie J
    Curr Oncol Rep; 2008 Mar; 10(2):107-13. PubMed ID: 18377823
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Identification and structure-activity relationships of ortho-biphenyl carboxamides as potent Smoothened antagonists inhibiting the Hedgehog signaling pathway.
    Peukert S; Jain RK; Geisser A; Sun Y; Zhang R; Bourret A; Carlson A; Dasilva J; Ramamurthy A; Kelleher JF
    Bioorg Med Chem Lett; 2009 Jan; 19(2):328-31. PubMed ID: 19091559
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Recent patents for Hedgehog pathway inhibitors for the treatment of malignancy.
    Tremblay MR; Nesler M; Weatherhead R; Castro AC
    Expert Opin Ther Pat; 2009 Aug; 19(8):1039-56. PubMed ID: 19505195
    [TBL] [Abstract][Full Text] [Related]  

  • 29. TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling.
    Ibuki N; Ghaffari M; Pandey M; Iu I; Fazli L; Kashiwagi M; Tojo H; Nakanishi O; Gleave ME; Cox ME
    Int J Cancer; 2013 Oct; 133(8):1955-66. PubMed ID: 23564295
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold.
    Berardozzi S; Bernardi F; Infante P; Ingallina C; Toscano S; De Paolis E; Alfonsi R; Caimano M; Botta B; Mori M; Di Marcotullio L; Ghirga F
    Eur J Med Chem; 2018 Aug; 156():554-562. PubMed ID: 30025349
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.
    Scales SJ; de Sauvage FJ
    Trends Pharmacol Sci; 2009 Jun; 30(6):303-12. PubMed ID: 19443052
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Targeting the hedgehog pathway: role in cancer and clinical implications of its inhibition.
    Cohen DJ
    Hematol Oncol Clin North Am; 2012 Jun; 26(3):565-88, viii. PubMed ID: 22520980
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists.
    Kim J; Aftab BT; Tang JY; Kim D; Lee AH; Rezaee M; Kim J; Chen B; King EM; Borodovsky A; Riggins GJ; Epstein EH; Beachy PA; Rudin CM
    Cancer Cell; 2013 Jan; 23(1):23-34. PubMed ID: 23291299
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Berberine, a natural compound, suppresses Hedgehog signaling pathway activity and cancer growth.
    Wang J; Peng Y; Liu Y; Yang J; Ding N; Tan W
    BMC Cancer; 2015 Aug; 15():595. PubMed ID: 26296751
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Hijacking the Hedgehog Pathway in Cancer Therapy.
    Laukkanen MO; Castellone MD
    Anticancer Agents Med Chem; 2016; 16(3):309-17. PubMed ID: 26443025
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Unraveling the therapeutic potential of the Hedgehog pathway in cancer.
    Amakye D; Jagani Z; Dorsch M
    Nat Med; 2013 Nov; 19(11):1410-22. PubMed ID: 24202394
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Digging a hole under Hedgehog: downstream inhibition as an emerging anticancer strategy.
    Di Magno L; Coni S; Di Marcotullio L; Canettieri G
    Biochim Biophys Acta; 2015 Aug; 1856(1):62-72. PubMed ID: 26080084
    [TBL] [Abstract][Full Text] [Related]  

  • 38. New developments in the discovery of small molecule Hedgehog pathway antagonists.
    Tremblay MR; McGovern K; Read MA; Castro AC
    Curr Opin Chem Biol; 2010 Jun; 14(3):428-35. PubMed ID: 20399136
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Hedgehog signaling pathway inhibitors: an updated patent review (2015-present).
    Quaglio D; Infante P; Di Marcotullio L; Botta B; Mori M
    Expert Opin Ther Pat; 2020 Apr; 30(4):235-250. PubMed ID: 32070165
    [No Abstract]   [Full Text] [Related]  

  • 40. Agents targeting the Hedgehog pathway for pancreatic cancer treatment.
    Bisht S; Brossart P; Maitra A; Feldmann G
    Curr Opin Investig Drugs; 2010 Dec; 11(12):1387-98. PubMed ID: 21154121
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.